Vobramitamab

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Approval Year

Substance Class	Protein Created by `admin` on `Wed Apr 02 04:37:11 GMT 2025` Edited by `admin` on `Wed Apr 02 04:37:11 GMT 2025`
Protein Type	MONOCLONAL ANTIBODY
Protein Sub Type	IGG1
Sequence Origin	HUMANIZED MOUSE
Sequence Type	COMPLETE
Record UNII	B4748B768U
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

Immunoglobulin G1 [de-447-lysine], anti-(human B7 homolog 3 protein)(human-Mus musculus monoclonal PRCA157 ?1-chain), disulfide with human-Mus musculus monoclonal PRCA157 ?-chain, dimer

Preferred Name

English

Vobramitamab

Official Name

English

VOBRAMITAMAB [USAN]

Common Name

English

MGC-017

Code

English

MGC017

Code

English

AEX-4089

Common Name

English

AEX4089

Code

English

vobramitamab [INN]

Common Name

English

MGA017 (HUMANIZED MONOCLONAL ANTIBODY THAT BINDS TO HUMAN B7-H3)

Common Name

English

Code System Code Type Description

FDA UNII

B4748B768U

Created by admin on Wed Apr 02 04:37:11 GMT 2025 , Edited by admin on Wed Apr 02 04:37:11 GMT 2025

PRIMARY

CAS

2490556-50-6

Created by admin on Wed Apr 02 04:37:11 GMT 2025 , Edited by admin on Wed Apr 02 04:37:11 GMT 2025

PRIMARY

INN

12057

Created by admin on Wed Apr 02 04:37:11 GMT 2025 , Edited by admin on Wed Apr 02 04:37:11 GMT 2025

PRIMARY

SMS_ID

300000043080

Created by admin on Wed Apr 02 04:37:11 GMT 2025 , Edited by admin on Wed Apr 02 04:37:11 GMT 2025

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NCI_THESAURUS

C203150

Created by admin on Wed Apr 02 04:37:11 GMT 2025 , Edited by admin on Wed Apr 02 04:37:11 GMT 2025

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USAN

KL-245

Created by admin on Wed Apr 02 04:37:11 GMT 2025 , Edited by admin on Wed Apr 02 04:37:11 GMT 2025

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From	To
1_22	1_96
1_144	1_200
1_220	3_215
1_226	2_226
1_229	2_229
1_261	1_321
1_367	1_425
2_22	2_96
2_144	2_200
2_220	4_215
2_261	2_321
2_367	2_425
3_23	3_88
3_135	3_195
4_23	4_88
4_135	4_195

Glycosylation Type

MAMMALIAN

Glycosylation Link Type	Site
N	1_297
N	2_297

Structural Modifications

Modification Type	Location Site	Location Type	Residue Modified	Extent	Fragment Name	Fragment Approval
AMINO ACID REMOVAL	[1_447] [2_447]	C-TERMINUS			LYSINE	K3Z4F929H6

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
Molecular Formula	CHEMICAL
MOL_WEIGHT:NUMBER(CALCULATED)	CHEMICAL