QUINAPYRAMINE

Details

Stereochemistry	ACHIRAL
Molecular Formula	C17H21N6
Molecular Weight	309.3888
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	1
Charge	1

SHOW SMILES / InChI

Structure Search

SMILES

CN1C(C)=C\C(=N\C2=CC=C3C(=C2)C(N)=CC(C)=[N+]3C)N=C1N

InChI

InChIKey=KMJWBVJQFGRCEB-UHFFFAOYSA-O

InChI=1S/C17H20N6/c1-10-7-14(18)13-9-12(5-6-15(13)22(10)3)20-16-8-11(2)23(4)17(19)21-16/h5-9,18H,1-4H3,(H2,19,20,21)/p+1

HIDE SMILES / InChI

Molecular Formula	C17H20N6
Molecular Weight	308.3809
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Approval Year

PubMed

Title	Date	PubMed
Studies of quinapyramine-resistance of Trypanosoma brucei evansi in China.	2010-12	20813092
In vitro activity and preliminary toxicity of various diamidine compounds against Trypanosoma evansi.	2010-05-11	20149544
Proteomics of Trypanosoma evansi infection in rodents.	2010-03-22	20339546
Immunobiology of African trypanosomes: need of alternative interventions.	2010	20182644
Genotypic status of the TbAT1/P2 adenosine transporter of Trypanosoma brucei gambiense isolates from Northwestern Uganda following melarsoprol withdrawal.	2009-09-29	19787038
Development and application of an antibody-ELISA to follow up a Trypanosoma evansi outbreak in a dromedary camel herd in France.	2009-06-10	19372008
Health management of horses under high challenge from trypanosomes: a case study from Serengeti, Tanzania.	2008-07-04	18450381
The history of African trypanosomiasis.	2008-02-12	18275594
The effect of TAO expression on PCD-like phenomenon development and drug resistance in Trypanosoma brucei.	2006-06	16516538
Resistance to drug by different isolates Trypanosoma evansi in China.	2004-05	15099814
RNA-interference silencing of the adenosine transporter-1 gene in Trypanosoma evansi confers resistance to diminazene aceturate.	2003-10-22	15208037
Antibody levels by indirect ELISA test in Trypanosoma evansi infected horses following treatment with quinapyramine sulphate.	2003-01-20	12523979
New drug developments for opportunistic infections in immunosuppressed patients: Pneumocystis carinii.	1995-11-24	7490723
Treatment of experimental pneumocystosis: review of 7 years of experience and development of a new system for classifying antimicrobial drugs.	1992-09	1416885
Cationic antitrypanosomal and other antimicrobial agents in the therapy of experimental Pneumocystis carinii pneumonia.	1988-06	3137861
Uridine 5'-diphosphate glucose analogues. Inhibitors of protein glycosylation that show antiviral activity.	1985-01	2981323

Patents

Substance Class	Chemical Created by `admin` on `Mon Mar 31 21:31:34 GMT 2025` Edited by `admin` on `Mon Mar 31 21:31:34 GMT 2025`
Record UNII	B2NT1100WR
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

NSC-48223

Preferred Name

English

QUINAPYRAMINE

Common Name

English

QUINAPYRAMINE ION

Common Name

English

QUINAPYRAMINE CATION

Common Name

English

QUINOLINIUM, 4-AMINO-6-((1,2-DIHYDRO-2-IMINO-1,6-DIMETHYL-4-PYRIMIDINYL)AMINO)-1,2-DIMETHYL-

Systematic Name

English

QUINAPYRAMINE [MI]

Common Name

English

Classification Tree Code System Code

WHO-VATC

QP51AX20