QUINAPYRAMINE

CN1C(C)=C\C(=N\C2=CC3=C(N)C=C(C)[N+](C)=C3C=C2)N=C1N

InChIKey=KMJWBVJQFGRCEB-UHFFFAOYSA-O

InChI=1S/C17H20N6/c1-10-7-14(18)13-9-12(5-6-15(13)22(10)3)20-16-8-11(2)23(4)17(19)21-16/h5-9,18H,1-4H3,(H2,19,20,21)/p+1

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

PubMed

Title	Date	PubMed
Uridine 5'-diphosphate glucose analogues. Inhibitors of protein glycosylation that show antiviral activity.	1985 Jan	2981323
Cationic antitrypanosomal and other antimicrobial agents in the therapy of experimental Pneumocystis carinii pneumonia.	1988 Jun	3137861
New drug developments for opportunistic infections in immunosuppressed patients: Pneumocystis carinii.	1995 Nov 24	7490723
Antibody levels by indirect ELISA test in Trypanosoma evansi infected horses following treatment with quinapyramine sulphate.	2003 Jan 20	12523979
The history of African trypanosomiasis.	2008 Feb 12	18275594
Health management of horses under high challenge from trypanosomes: a case study from Serengeti, Tanzania.	2008 Jul 4	18450381
Development and application of an antibody-ELISA to follow up a Trypanosoma evansi outbreak in a dromedary camel herd in France.	2009 Jun 10	19372008
Genotypic status of the TbAT1/P2 adenosine transporter of Trypanosoma brucei gambiense isolates from Northwestern Uganda following melarsoprol withdrawal.	2009 Sep 29	19787038
Immunobiology of African trypanosomes: need of alternative interventions.	2010	20182644
Studies of quinapyramine-resistance of Trypanosoma brucei evansi in China.	2010 Dec	20813092
Proteomics of Trypanosoma evansi infection in rodents.	2010 Mar 22	20339546
In vitro activity and preliminary toxicity of various diamidine compounds against Trypanosoma evansi.	2010 May 11	20149544

Patents

Substance Class	Chemical Created by `admin` on `Sat Dec 16 05:40:25 GMT 2023` Edited by `admin` on `Sat Dec 16 05:40:25 GMT 2023`
Record UNII	B2NT1100WR
Record Status	`Validated (UNII)`
Record Version

Name

Type

Language

QUINAPYRAMINE

Common Name

English

QUINAPYRAMINE ION

Common Name

English

QUINAPYRAMINE CATION

Common Name

English

QUINOLINIUM, 4-AMINO-6-((1,2-DIHYDRO-2-IMINO-1,6-DIMETHYL-4-PYRIMIDINYL)AMINO)-1,2-DIMETHYL-

Systematic Name

English

NSC-48223

Code

English

QUINAPYRAMINE [MI]

Common Name

English

Classification Tree Code System Code

WHO-VATC

QP51AX20