MITOGEN-ACTIVATED PROTEIN KINASE 8

Approval Year

Substance Class	Protein
Protein Sub Type
Sequence Origin	HUMAN
Sequence Type	COMPLETE
Record UNII	B2BR0KE2T8
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

C-JUN N-TERMINAL KINASE 1

Preferred Name

English

MITOGEN-ACTIVATED PROTEIN KINASE 8

Common Name

English

MAP KINASE 8

Common Name

English

SAPK1C

Common Name

English

JNK1

Common Name

English

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Code System

Code

Type

Description

FDA UNII

B2BR0KE2T8

PRIMARY

WIKIPEDIA

MAPK8

PRIMARY

PHAROS

P45983

PRIMARY

UNIPROT

P45983

PRIMARY

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Related Record

Type

Details


					2K30142185

BRIMAPITIDE

INHIBITOR -> TARGET


					K6K4B9Z5TV

IVARMACITINIB

INHIBITOR -> TARGET


					M5O06306UO

TANZISERTIB

INHIBITOR -> TARGET

Amount:


					JD5ZWE631K

CC-90001

INHIBITOR -> TARGET

Amount:

480 NANOMOLAR (average)


					TT3L4B4U0N

BENTAMAPIMOD

INHIBITOR -> TARGET

Qualification:

IC50

Amount:

150 NANOMOLAR (average)

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Structural Modifications

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Modification Type	Location Site	Location Type	Residue Modified	Extent	Fragment Name	Fragment Approval
AMINO ACID SUBSTITUTION	[1_116]				S-NITROSOCYSTEINE	926P2322P4

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Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
MOL_WEIGHT	CHEMICAL

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