TRIS(1,3-DICHLORO-2-PROPYL)PHOSPHATE

Details

Stereochemistry	ACHIRAL
Molecular Formula	C9H15Cl6O4P
Molecular Weight	430.905
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of TRIS(1,3-DICHLORO-2-PROPYL)PHOSPHATE

Structure Search

SMILES

ClCC(CCl)OP(=O)(OC(CCl)CCl)OC(CCl)CCl

InChI

InChIKey=ASLWPAWFJZFCKF-UHFFFAOYSA-N

InChI=1S/C9H15Cl6O4P/c10-1-7(2-11)17-20(16,18-8(3-12)4-13)19-9(5-14)6-15/h7-9H,1-6H2

HIDE SMILES / InChI

Molecular Formula	C9H15Cl6O4P
Molecular Weight	430.905
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Approval Year

PubMed

Title	Date	PubMed
In vitro dermal absorption of flame retardant chemicals.	2001 Dec	11696400
Estimation of organophosphoric acid triesters in soft polyurethane foam using a concentrated sulfuric acid dissolution technique and gas chromatography with flame photometric detection.	2003 Dec	14696924
Organophosphate flame retardants and plasticizers in indoor air.	2004 Nov	15488569
Enrichment and characterization of chlorinated organophosphate ester-degrading mixed bacterial cultures.	2008 Jul	18691527
Detection of organophosphate flame retardants in furniture foam and U.S. house dust.	2009 Oct 1	19848166
Discontinued pajama flame retardant detected in baby products and house dust.	2009 Oct 1	19848114
Seasonal fluctuations of organophosphate concentrations in precipitation and storm water runoff.	2010 Feb	20074776
Endocrine damper? Flame retardants linked to male hormone, sperm count changes.	2010 Mar	20194076
House dust concentrations of organophosphate flame retardants in relation to hormone levels and semen quality parameters.	2010 Mar	20194068
Endocrine disruption potentials of organophosphate flame retardants and related mechanisms in H295R and MVLN cell lines and in zebrafish.	2012 Jun 15	22446829
Effects of tris(1,3-dichloro-2-propyl) phosphate and tris(1-chloropropyl) phosphate on cytotoxicity and mRNA expression in primary cultures of avian hepatocytes and neuronal cells.	2012 Mar	22268003
Effects of tris(1,3-dichloro-2-propyl) phosphate and triphenyl phosphate on receptor-associated mRNA expression in zebrafish embryos/larvae.	2013 Mar 15	23306105
Similarities in the endocrine-disrupting potencies of indoor dust and flame retardants by using human osteosarcoma (U2OS) cell-based reporter gene assays.	2013 Mar 19	23398518
Toxicogenomic responses of zebrafish embryos/larvae to tris(1,3-dichloro-2-propyl) phosphate (TDCPP) reveal possible molecular mechanisms of developmental toxicity.	2013 Sep 17	23919627
Developmental exposure to organophosphate flame retardants elicits overt toxicity and alters behavior in early life stage zebrafish (Danio rerio).	2014 Dec	25239634
Toxicity of TDCPP and TCEP on PC12 cell: changes in CAMKII, GAP43, tubulin and NF-H gene and protein levels.	2014 Jun 16	24717766
Potential estrogenic effects of phosphorus-containing flame retardants.	2014 Jun 17	24844797
Multiple bio-analytical methods to reveal possible molecular mechanisms of developmental toxicity in zebrafish embryos/larvae exposed to tris(2-butoxyethyl) phosphate.	2014 May	24685621
Elucidating mechanisms of toxicity using phenotypic data from primary human cell systems--a chemical biology approach for thrombosis-related side effects.	2015 Jan 5	25569083
The Flame-Retardant Tris(1,3-dichloro-2-propyl) Phosphate Represses Androgen Signaling in Human Prostate Cancer Cell Lines.	2016 May	26709203

Substance Class	Chemical Created by `admin` on `Fri Dec 15 18:36:11 GMT 2023` Edited by `admin` on `Fri Dec 15 18:36:11 GMT 2023`
Record UNII	B1PRV4G0T0
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

TRIS(1,3-DICHLORO-2-PROPYL)PHOSPHATE

Systematic Name

English

TRIS(1,3-DICHLORO-2-PROPYL)PHOSPHATE [HSDB]

Common Name

English

TDCPP

Common Name

English

TRIS(1,3-DICHLOROISOPROPYL)PHOSPHATE

Common Name

English

FYROL FR-2

Brand Name

English

TDCPP [MI]

Common Name

English

TRIS(1,3-DICHLORO-2-PROPYL) PHOSPHATE

Systematic Name

English

Code System Code Type Description

ECHA (EC/EINECS)

237-159-2