PROSTAGLANDIN G2

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C20H32O6
Molecular Weight	368.4645
Optical Activity	UNSPECIFIED
Defined Stereocenters	5 / 5
E/Z Centers	2
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CCCCC[C@H](OO)\C=C\[C@H]1[C@H]2C[C@H](OO2)[C@@H]1C\C=C/CCCC(O)=O

InChI

InChIKey=SGUKUZOVHSFKPH-YNNPMVKQSA-N

InChI=1S/C20H32O6/c1-2-3-6-9-15(24-23)12-13-17-16(18-14-19(17)26-25-18)10-7-4-5-8-11-20(21)22/h4,7,12-13,15-19,23H,2-3,5-6,8-11,14H2,1H3,(H,21,22)/b7-4-,13-12+/t15-,16+,17+,18-,19+/m0/s1

HIDE SMILES / InChI

Molecular Formula	C20H32O6
Molecular Weight	368.4645
Charge	0
Count

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	5 / 5
E/Z Centers	2
Optical Activity	UNSPECIFIED

Approval Year

Targets

Primary Target	Pharmacology	Condition	Potency
Nitric oxide synthase, brain 4 Target ID: P29476 Gene ID: 24598.0 Gene Symbol: Nos1 Target Organism: Rattus norvegicus (Rat) Sources: https://www.ncbi.nlm.nih.gov/pubmed/11500026	Activator 1430		0.5 µM [EC50]

PubMed

Title	Date	PubMed
The cyclooxygenase hydroperoxide product PGG(2) activates synaptic nitric oxide synthase: a possible antioxidant response to membrane lipid peroxidation.	2001 Aug 17	11500026

Substance Class	Chemical Created by `admin` on `Sat Dec 16 18:15:55 GMT 2023` Edited by `admin` on `Sat Dec 16 18:15:55 GMT 2023`
Record UNII	AZ87DUD2Y8
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

PROSTAGLANDIN G2

Common Name

English

(5Z,9.ALPHA.,11.ALPHA.,13E,15S)-9,11-EPIDIOXY-15-HYDROPEROXYPROSTA-5,13-DIEN-1-OIC ACID

Systematic Name

English

PGG2

Common Name

English

ENDOPEROXIDE G2

Common Name

English

(5Z)-7-((1R,4S,5R,6R)-6-((1E,3S)-3-HYDROPEROXY-1-OCTEN-1-YL)-2,3-DIOXABICYCLO(2.2.1)HEPT-5-YL)-5-HEPTENOIC ACID

Systematic Name

English

Code System Code Type Description

CHEBI

27647