PEGNIVACOGIN

Investigational

Approval Year

Substance Class	Nucleic Acid
Record UNII	AYC3D1NPYB
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

pegnivacogin [INN]

Preferred Name

English

PEGNIVACOGIN

Official Name

English

RB-006

Code

English

PEGNIVACOGIN [USAN]

Common Name

English

Pegnivacogin [WHO-DD]

Common Name

English

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Code System

Code

Type

Description

USAN

XX-98

PRIMARY

PUBCHEM

86278323

PRIMARY

CAS

959716-28-0

PRIMARY

FDA UNII

AYC3D1NPYB

PRIMARY

SMS_ID

300000034345

PRIMARY

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Subunit 0

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Sugar	Site Range	Site Count
Deoxyribose (DNA)	1_31	1 / 31
D-Ribose (RNA)	1_23	1 / 31
2'-Fluoro-Ribose	1_6-1_7;1_9;1_11-1_12;1_14;1_16;1_19;1_21;1_25-1_26	11 / 31
2'-O-Methyl-Ribose	1_1-1_5;1_8;1_10;1_13;1_15;1_17-1_18;1_20;1_22;1_24;1_27-1_30	18 / 31

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Linkage	Site Range	Site Count
Phosphate	1_2-1_31	30 / 30

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					4OXU6KPQ3R

ANIVAMERSEN

ANTIDOTE->ANTICOAGULANT

Amount:


					Q9Z4S53HYH

Coagulation factor IXa

TARGET -> INHIBITOR

Amount:


					Z219A1184Z

PEGNIVACOGIN SODIUM

SALT/SOLVATE -> PARENT

Amount:

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Type

Details


					AYC3D1NPYB

PEGNIVACOGIN

ACTIVE MOIETY

Amount:

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Agent Modifications

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Modification Process	Modification Role	Modification Type	Amount	Fragment Name	Fragment ID

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Structural Modifications

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Modification Type	Location Site	Location Type	Residue Modified	Extent	Fragment Name	Fragment Approval
NUCLEOTIDE SUBSTITUTION	[1_31]	SITE_SPECIFIC			RIBOTHYMIDINE 3'-MONOPHOSPHATE	796M1I7H8N
NUCLEOSIDE_SUBSTITUTION	[1_1]	5'-TERMINUS			PEGNIVACOGIN GUANOSINE 5' MODIFICATION	GB00680LD3

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Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
MOL_WEIGHT:NUMBER(CALCULATED)	CHEMICAL	NUMBER 50.53 kDa (average)

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