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Approval Year

Unknown
149124
Substance Class Protein
Created
by admin
on Wed Apr 02 00:11:42 GMT 2025
Edited
by admin
on Wed Apr 02 00:11:42 GMT 2025
Protein Type MONOCLONAL ANTIBODY
Protein Sub Type IGG4
Sequence Origin HUMANIZED MOUSE
Sequence Type COMPLETE
Record UNII
AY6V5E2GNX
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
LY-3303560
Preferred Name English
ZAGOTENEMAB
INN   USAN  
Official Name English
zagotenemab [INN]
Common Name English
Zagotenemab [WHO-DD]
Common Name English
LY3303560
Code English
IMMUNOGLOBULIN G4, ANTI-(TAU PROTEIN) (HUMAN MONOCLONAL LY3303560 .GAMMA.4-CHAIN), DISULFIDE WITH HUMAN MONOCLONAL LY3303560 LIGHT CHAIN, DIMER
Common Name English
IMMUNOGLOBULIN G4-KAPPA, ANTI-(HOMO SAPIENS MICROTUBULE-ASSOCIATED PROTEIN TAU (NEUROFIBRILLARY TANGLE PROTEIN, PHF-TAU)) HUMANIZED MONOCLONAL ANTIBODY .GAMMA.4 HEAVY CHAIN (1-442) (HUMANIZED VH (HOMO SAPIENS IGHV5-51*01 (85%) (IGHD)-IGHJ4*01 (87%)) (8.8
Common Name English
ZAGOTENEMAB [USAN]
Common Name English
Code System Code Type Description
CAS
2019133-28-7
Created by admin on Wed Apr 02 00:11:42 GMT 2025 , Edited by admin on Wed Apr 02 00:11:42 GMT 2025
PRIMARY
FDA UNII
AY6V5E2GNX
Created by admin on Wed Apr 02 00:11:42 GMT 2025 , Edited by admin on Wed Apr 02 00:11:42 GMT 2025
PRIMARY
USAN
FG-107
Created by admin on Wed Apr 02 00:11:42 GMT 2025 , Edited by admin on Wed Apr 02 00:11:42 GMT 2025
PRIMARY
INN
11050
Created by admin on Wed Apr 02 00:11:42 GMT 2025 , Edited by admin on Wed Apr 02 00:11:42 GMT 2025
PRIMARY
SMS_ID
300000010808
Created by admin on Wed Apr 02 00:11:42 GMT 2025 , Edited by admin on Wed Apr 02 00:11:42 GMT 2025
PRIMARY
NCI_THESAURUS
C171842
Created by admin on Wed Apr 02 00:11:42 GMT 2025 , Edited by admin on Wed Apr 02 00:11:42 GMT 2025
PRIMARY
From To
1_22 1_96
2_22 2_96
2_130 4_219
2_143 2_199
2_257 2_317
1_130 3_219
2_363 2_421
3_23 3_93
3_139 3_199
4_23 4_93
4_139 4_199
1_143 1_199
1_222 2_222
1_225 2_225
1_257 1_317
1_363 1_421
Glycosylation Type MAMMALIAN
Glycosylation Link Type Site
N 1_293
N 2_293
Related Record Type Details
MICROTUBULE-ASSOCIATED PROTEIN TAU (PAIRED HELICAL FILAMENTS (PHF))
TARGET->LIGAND
Designed to bind to and neutralize tau clumps, slowing or stopping the worsening of Alzheimer’s.
Related Record Type Details
ZAGOTENEMAB
ACTIVE MOIETY
Name Property Type Amount Referenced Substance Defining Parameters References
MOL_WEIGHT:NUMBER(CALCULATED) CHEMICAL
Molecular Formula CHEMICAL
NIH
NCATS
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