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Details

Stereochemistry ABSOLUTE
Molecular Formula C23H18ClFN6O2
Molecular Weight 464.879
Optical Activity UNSPECIFIED
Additional Stereochemistry Yes
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0
Stereo Comments AXIAL, S

SHOW SMILES / InChI
Structure of MRTX-1719

SMILES

CN1N=CC(=C1C2=C(C#N)C(OC3CC3)=CC(Cl)=C2F)C4=CC=C5C(=O)NN=C(CN)C5=C4

InChI

InChIKey=BZKIOORWZAXIBA-UHFFFAOYSA-N
InChI=1S/C23H18ClFN6O2/c1-31-22(20-15(8-26)19(33-12-3-4-12)7-17(24)21(20)25)16(10-28-31)11-2-5-13-14(6-11)18(9-27)29-30-23(13)32/h2,5-7,10,12H,3-4,9,27H2,1H3,(H,30,32)

HIDE SMILES / InChI

Molecular Formula C23H18ClFN6O2
Molecular Weight 464.879
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Approval Year

Substance Class Chemical
Created
by admin
on Sat Dec 16 18:29:52 GMT 2023
Edited
by admin
on Sat Dec 16 18:29:52 GMT 2023
Record UNII
AY4A8WD6JS
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
MRTX-1719
Code English
BENZONITRILE, 2-(4-(4-(AMINOMETHYL)-1,2-DIHYDRO-1-OXO-6-PHTHALAZINYL)-1-METHYL-1H-PYRAZOL-5-YL)-4-CHLORO-6-(CYCLOPROPYLOXY)-3-FLUORO-, (2S)-
Systematic Name English
(2M)-2-(4-(4-(aminomethyl)-1-oxo-1,2-dihydrophthalazin-6-yl)-1-methyl-1H-pyrazol-5-yl)-4-chloro-6-cyclopropoxy-3-fluorobenzonitrile
Systematic Name English
Classification Tree Code System Code
FDA ORPHAN DRUG 934823
Created by admin on Sat Dec 16 18:29:52 GMT 2023 , Edited by admin on Sat Dec 16 18:29:52 GMT 2023
Code System Code Type Description
FDA UNII
AY4A8WD6JS
Created by admin on Sat Dec 16 18:29:52 GMT 2023 , Edited by admin on Sat Dec 16 18:29:52 GMT 2023
PRIMARY
CAS
2630904-44-6
Created by admin on Sat Dec 16 18:29:52 GMT 2023 , Edited by admin on Sat Dec 16 18:29:52 GMT 2023
PRIMARY
PUBCHEM
156151242
Created by admin on Sat Dec 16 18:29:52 GMT 2023 , Edited by admin on Sat Dec 16 18:29:52 GMT 2023
PRIMARY
NCI_THESAURUS
C187048
Created by admin on Sat Dec 16 18:29:52 GMT 2023 , Edited by admin on Sat Dec 16 18:29:52 GMT 2023
PRIMARY
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