TIAPROST TROMETHAMINE

Details

Stereochemistry	EPIMERIC
Molecular Formula	C20H28O6S.C4H11NO3
Molecular Weight	517.633
Optical Activity	UNSPECIFIED
Defined Stereocenters	4 / 5
E/Z Centers	2
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

NC(CO)(CO)CO.OC(COC1=CSC=C1)\C=C\[C@H]2[C@H](O)C[C@H](O)[C@@H]2C\C=C/CCCC(O)=O

InChI

InChIKey=ANXQNUUWCDBQFB-YXDKQNBXSA-N

InChI=1S/C20H28O6S.C4H11NO3/c21-14(12-26-15-9-10-27-13-15)7-8-17-16(18(22)11-19(17)23)5-3-1-2-4-6-20(24)25;5-4(1-6,2-7)3-8/h1,3,7-10,13-14,16-19,21-23H,2,4-6,11-12H2,(H,24,25);6-8H,1-3,5H2/b3-1-,8-7+;/t14?,16-,17-,18+,19-;/m1./s1

HIDE SMILES / InChI

Molecular Formula	C20H28O6S
Molecular Weight	396.498
Charge	0
Count

Stereochemistry	EPIMERIC
Additional Stereochemistry	No
Defined Stereocenters	4 / 5
E/Z Centers	2
Optical Activity	UNSPECIFIED

Molecular Formula	C4H11NO3
Molecular Weight	121.135
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/15725435 | https://www.ncbi.nlm.nih.gov/pubmed/16320570 | https://www.ncbi.nlm.nih.gov/pubmed/6428028

Tiaprost is a synthetic analog of prostaglandin F2α (PGF2α) patented by Hoechst A.-G. as an estrus-synchronizing agent for veterinary medicine. Tiaprost treatment reduced the interval from calving to conception in multiparous cows, but it delayed conception and reduced the conception rate in primiparous cows. Treatment with tiaprost impaired reproductive performance in primiparous cows

Originator

Approval Year

PubMed

Title	Date	PubMed
Luteolysis in cows using the prostaglandin F2 alpha analogue, tiaprost, and the effect of mode of administration.	1984-04-28	6428028

Patents

Sample Use Guides

In Vivo Use Guide

cows: 0.75 mg

Route of Administration: Other

Substance Class	Chemical Created by `admin` on `Mon Mar 31 21:54:32 GMT 2025` Edited by `admin` on `Mon Mar 31 21:54:32 GMT 2025`
Record UNII	AW1M28737K
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

TIAPROST TROMETHAMINE

Common Name

English

TIAPROST TROMETHAMINE SALT

Preferred Name

English

TIAPROST TROMETAMOL

Common Name

English

ILIREN

Brand Name

English

TIAPROST TROMETHAMINE SALT [MI]

Common Name

English

TIAPROST, (R,S)-, COMPOUND WITH TROMETHAMINE

Common Name

English

7-(3,5-DIHYDROXY-2-(3-HYDROXY-4-(3-THIENYLOXY)-1-BUTENYL)CYCLOPENTYL)-5-HEPTENOIC ACID TROMETHAMINE SALT

Systematic Name

English

Code System Code Type Description

CAS

71116-83-1