MANOOL

C[C@@](O)(CC[C@H]1C(=C)CC[C@H]2C(C)(C)CCC[C@]12C)C=C

InChIKey=CECREIRZLPLYDM-QGZVKYPTSA-N

InChI=1S/C20H34O/c1-7-19(5,21)14-11-16-15(2)9-10-17-18(3,4)12-8-13-20(16,17)6/h7,16-17,21H,1-2,8-14H2,3-6H3/t16-,17-,19-,20+/m0/s1

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	4 / 4
E/Z Centers	0
Optical Activity	UNSPECIFIED

Targets

Primary Target	Pharmacology	Condition	Potency
M phase 1 Target ID: GO:0000279 Sources: https://www.ncbi.nlm.nih.gov/pubmed/20132046	Inhibitor 8504
G2 phase 1 Target ID: GO:0051319 Sources: https://www.ncbi.nlm.nih.gov/pubmed/20132046	Inhibitor 8504

PubMed

Title	Date	PubMed
Manool, a Salvia officinalis diterpene, induces selective cytotoxicity in cancer cells.	2016-10	26547581
Differential effect of manool--a diterpene from Salvia officinalis, on genotoxicity induced by methyl methanesulfonate in V79 and HepG2 cells.	2014-10	25007786

Substance Class	Chemical Created by `admin` on `Mon Mar 31 18:54:26 GMT 2025` Edited by `admin` on `Mon Mar 31 18:54:26 GMT 2025`
Record UNII	AT5PJ0PV00
Record Status	`Validated (UNII)`
Record Version

Name

Type

Language

MANOOL

Common Name

English

NSC-165961

Preferred Name

English

1-NAPHTHALENEPROPANOL, .ALPHA.-ETHENYLDECAHYDRO-.ALPHA.,5,5,8A-TETRAMETHYL-2-METHYLENE-, (.ALPHA.R,1S,4AS,8AS)-

Common Name

English

(.ALPHA.R,1S,4AS,8AS)-.ALPHA.-ETHENYLDECAHYDRO-.ALPHA.,5,5,8A-TETRAMETHYL-2-METHYLENE-1-NAPHTHALENEPROPANOL

Common Name

English

LABDA-8(20),14-DIEN-13-OL, (13R)-

Common Name

English

Code System Code Type Description

CAS

596-85-0