GUANOXABENZ HYDROCHLORIDE

Details

Stereochemistry	ACHIRAL
Molecular Formula	C8H8Cl2N4O.ClH
Molecular Weight	283.542
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	1
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

Cl.ONC(=N)N\N=C\C1=C(Cl)C=CC=C1Cl

InChI

InChIKey=PQPZROSFRCBPIM-AQCBZIOHSA-N

InChI=1S/C8H8Cl2N4O.ClH/c9-6-2-1-3-7(10)5(6)4-12-13-8(11)14-15;/h1-4,15H,(H3,11,13,14);1H/b12-4+;

HIDE SMILES / InChI

Molecular Formula	C8H8Cl2N4O
Molecular Weight	247.081
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	1
Optical Activity	NONE

Molecular Formula	ClH
Molecular Weight	36.461
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/7258704 | https://www.ncbi.nlm.nih.gov/pubmed/7914222 | https://www.ncbi.nlm.nih.gov/pubmed/9351903

Guanoxabenz is an antihypertensive drug that was in clinical use in the 1980s. It acts as a selective agonist of alpha2A1 and alpha2B1 adrenergic receptors. Guanoxabenz is the main metabolite of the FDA-approved drug guanabenz.

Approval Year

PubMed

Title	Date	PubMed
Neuropharmacological studies in rodents on the action of RX 781094, a new selective alpha 2-adrenoceptor antagonist.	1983 Jun	6136932

Substance Class	Chemical Created by `admin` on `Sat Dec 16 15:19:44 GMT 2023` Edited by `admin` on `Sat Dec 16 15:19:44 GMT 2023`
Record UNII	ASL1V61E48
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

GUANOXABENZ HYDROCHLORIDE

Common Name

English

2-((2,6-DICHLOROPHENYL)METHYLENE)-N-HYDROXYHYDRAZINECARBOXIMIDAMIDE, HYDROCHLORIDE

Systematic Name

English

GUANOXABENZ HYDROCHLORIDE [MI]

Common Name

English

BENZERIAL

Brand Name

English

HYDRAZINECARBOXIMIDAMIDE, 2-((2,6-DICHLOROPHENYL)METHYLENE)-N-HYDROXY-, HYDROCHLORIDE (1:1)

Systematic Name

English

Code System Code Type Description

FDA UNII

ASL1V61E48