BLESELUMAB

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Approval Year

Substance Class	Protein Created by `admin` on `Sat Dec 16 10:41:23 GMT 2023` Edited by `admin` on `Sat Dec 16 10:41:23 GMT 2023`
Protein Type	MONOCLONAL ANTIBODY
Protein Sub Type	IGG4
Sequence Origin	HUMAN
Sequence Type	COMPLETE
Record UNII	AS3AZ5R46K
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

BLESELUMAB

Official Name

English

bleselumab [INN]

Common Name

English

Bleselumab [WHO-DD]

Common Name

English

IMMUNOGLOBULIN G4-KAPPA, ANTI-(HOMO SAPIENS CD40 (TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 5, TNFRSF5)), HUMAN MONOCLONAL ANTIBODY

Common Name

English

IMMUNOGLOBULIN G4-KAPPA, ANTI-(HOMO SAPIENS CD40 (TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 5, TNFRSF5)), HUMAN MONOCLONAL ANTIBODY GAMMA4 HEAVY CHAIN (1-448) (HOMO SAPIENS VH (IGHV4- 39*01 (92.90%) -(IGHD)-IGHJ5*01) (10.7.13) (1-121) - IGHG4*01

Systematic Name

English

IMMUNOGLOBULIN G4, ANTI-(HUMAN CD40 ANTIGEN) (HUMAN MONOCLONAL ASKP1240 HEAVY CHAIN), DISULFIDE WITH HUMAN MONOCLONAL ASKP1240 LIGHT CHAIN, DIMER

Common Name

English

ASKP1240

Code

English

ASKP-1240

Code

English

BLESELUMAB [USAN]

Common Name

English

Code System Code Type Description

CAS

1453067-91-8

Created by admin on Sat Dec 16 10:41:23 GMT 2023 , Edited by admin on Sat Dec 16 10:41:23 GMT 2023

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WIKIPEDIA

Bleselumab

Created by admin on Sat Dec 16 10:41:23 GMT 2023 , Edited by admin on Sat Dec 16 10:41:23 GMT 2023

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NCI_THESAURUS

C171700

Created by admin on Sat Dec 16 10:41:23 GMT 2023 , Edited by admin on Sat Dec 16 10:41:23 GMT 2023

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USAN

EF-27

Created by admin on Sat Dec 16 10:41:23 GMT 2023 , Edited by admin on Sat Dec 16 10:41:23 GMT 2023

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FDA UNII

AS3AZ5R46K

Created by admin on Sat Dec 16 10:41:23 GMT 2023 , Edited by admin on Sat Dec 16 10:41:23 GMT 2023

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INN

10114

Created by admin on Sat Dec 16 10:41:23 GMT 2023 , Edited by admin on Sat Dec 16 10:41:23 GMT 2023

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DRUG BANK

DB15253

Created by admin on Sat Dec 16 10:41:23 GMT 2023 , Edited by admin on Sat Dec 16 10:41:23 GMT 2023

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From	To
1_22	1_97
1_148	1_204
1_262	1_322
1_368	1_426
2_22	2_97
2_148	2_204
2_262	2_322
2_368	2_426
3_23	3_88
3_133	3_193
4_23	4_88
4_133	4_193
1_135	3_213
2_135	4_213
1_227	2_227
1_230	2_230

Glycosylation Type

MAMMALIAN

Glycosylation Link Type	Site
N	1_298
N	2_298

Related Record Type Details


					CA9PO31PIJ

TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 5

TARGET -> INHIBITOR

Related Record Type Details


					AS3AZ5R46K

ACTIVE MOIETY

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
MOL_WEIGHT:NUMBER(CALCULATED)	CHEMICAL
Molecular Formula	CHEMICAL