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Details

Stereochemistry ACHIRAL
Molecular Formula C15H10N2O2
Molecular Weight 250.2521
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 2
Charge 0

SHOW SMILES / InChI
Structure of DIPHENYLMETHANE-2,2'-DIISOCYANATE

SMILES

O=C=NC1=CC=CC=C1CC2=C(C=CC=C2)N=C=O

InChI

InChIKey=JIABEENURMZTTI-UHFFFAOYSA-N
InChI=1S/C15H10N2O2/c18-10-16-14-7-3-1-5-12(14)9-13-6-2-4-8-15(13)17-11-19/h1-8H,9H2

HIDE SMILES / InChI

Molecular Formula C15H10N2O2
Molecular Weight 250.2521
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 2
Optical Activity NONE

Approval Year

PubMed

PubMed

TitleDatePubMed
Dermal and inhalation exposure to methylene bisphenyl isocyanate (MDI) in iron foundry workers.
2010-01
Biological monitoring of workers exposed to 4,4'-methylenediphenyl diisocyanate (MDI) in 19 French polyurethane industries.
2007-04
Skin exposure to isocyanates: reasons for concern.
2007-03
Analysis of biomarkers in rats and dogs exposed to polymeric methylenediphenyl diisocyanate (pMDI) and its glutathione adduct.
2006-05-15
An FTIR investigation of isocyanate skin absorption using in vitro guinea pig skin.
2006-05
Kinetics and mechanistic studies of the hydrolysis of diisocyanate-derived bis-thiocarbamates of cysteine methyl ester.
2006-03
Determination of technical grade isocyanates used in the production of polyurethane plastics.
2004-07
Identification and characterisation of adducts between serum albumin and 4,4'-methylenediphenyl diisocyanate (MDI) in human plasma.
2004-07
Hydrolytic stability of toluene diisocyanate and polymeric methylenediphenyl diisocyanate based polyureas under environmental conditions.
2004-02-15
Fate and potential environmental effects of methylenediphenyl diisocyanate and toluene diisocyanate released into the atmosphere.
2003-01
Synthesis, characterization, and solvolysis of mono- and bis-S-(glutathionyl) adducts of methylene-bis-(phenylisocyanate) (MDI).
2002-10
Analysis of markers of exposure to polymeric methylene-diphenyl diisocyanate (pMDI) in rats: a comparison of dermal and inhalation routes of exposure.
2002-08
Sister chromatid exchanges and micronuclei in peripheral lymphocytes of shoe factory workers exposed to solvents.
2002-04
Morphology and structure of microcapsules prepared by interfacial polycondensation of methylene bis(phenyl isocyanate) with hexamethylene diamine.
2001-11-07
Exposure to chemical agents in Swedish aluminum foundries and aluminum remelting plants--a comprehensive survey.
2001-01
Patents
Substance Class Chemical
Created
by admin
on Mon Mar 31 22:01:01 GMT 2025
Edited
by admin
on Mon Mar 31 22:01:01 GMT 2025
Record UNII
AS00FWT3DM
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
DIPHENYLMETHANE-2,2'-DIISOCYANATE
Common Name English
2,2'-DIISOCYANATODIPHENYLMETHANE
Preferred Name English
ISOCYANIC ACID, METHYLENEDI-O-PHENYLENE ESTER
Systematic Name English
BENZENE, 1,1'-METHYLENEBIS(2-ISOCYANATO-
Systematic Name English
2,2'-METHYLENEDI(PHENYL ISOCYANATE)
Common Name English
DIPHENYLMETHANE 2,2'-DIISOCYANATE
Common Name English
Code System Code Type Description
EPA CompTox
DTXSID90883107
Created by admin on Mon Mar 31 22:01:01 GMT 2025 , Edited by admin on Mon Mar 31 22:01:01 GMT 2025
PRIMARY
PUBCHEM
62450
Created by admin on Mon Mar 31 22:01:01 GMT 2025 , Edited by admin on Mon Mar 31 22:01:01 GMT 2025
PRIMARY
FDA UNII
AS00FWT3DM
Created by admin on Mon Mar 31 22:01:01 GMT 2025 , Edited by admin on Mon Mar 31 22:01:01 GMT 2025
PRIMARY
ECHA (EC/EINECS)
219-799-4
Created by admin on Mon Mar 31 22:01:01 GMT 2025 , Edited by admin on Mon Mar 31 22:01:01 GMT 2025
PRIMARY
CAS
2536-05-2
Created by admin on Mon Mar 31 22:01:01 GMT 2025 , Edited by admin on Mon Mar 31 22:01:01 GMT 2025
PRIMARY