U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS
This repository is under review for potential modification in compliance with Administration directives.

Details

Stereochemistry ACHIRAL
Molecular Formula C2H7N
Molecular Weight 45.0837
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of Dimethylamine

SMILES

CNC

InChI

InChIKey=ROSDSFDQCJNGOL-UHFFFAOYSA-N
InChI=1S/C2H7N/c1-3-2/h3H,1-2H3

HIDE SMILES / InChI

Molecular Formula C2H7N
Molecular Weight 45.0837
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Approval Year

PubMed

PubMed

TitleDatePubMed
O-Methylephedrine: a versatile and highly efficient ortho-directing group. Synthesis of enantiopure 1,2-disubstituted ferrocene derivatives.
2001 Dec 28
Reactivity of a titanium dinitrogen complex supported by guanidinate ligands: investigation of solution behavior and a novel rearrangement of guanidinate ligands.
2001 Dec 31
O-Phosphonatomethylcholine, its analogues, alkyl esters, and their biological activity.
2001 Dec 6
3,6-Bis(dimethylamino)-10-propylacridinium iodide.
2001 Nov
An orally active, water-soluble neurokinin-1 receptor antagonist suitable for both intravenous and oral clinical administration.
2001 Nov 22
Syntheses of puromycin from adenosine and 7-deazapuromycin from tubercidin, and biological comparisons of the 7-aza/deaza pair.
2001 Nov 30
Identification of substituted sites on MUC5AC mucin motif peptides after enzymatic O-glycosylation combining beta-elimination and fixed-charge derivatization.
2002
Mechanistic studies of N-nitrosodimethylamine (NDMA) formation in chlorinated drinking water.
2002 Apr
Interactions of the anticancer antibiotic altromycin B with copper(II), palladium(II) and platinum(II) ions and in vitro activity of the formed complexes.
2002 Apr 10
Proton transfer reactions on semiconductor surfaces.
2002 Apr 17
Variable-temperature nuclear magnetic resonance spectroscopy allows direct observation of carboxylate shift in zinc carboxylate complexes.
2002 Apr 17
6-[2-(Phosphonomethoxy)alkoxy]pyrimidines with antiviral activity.
2002 Apr 25
Dimethylformamide as a carbon monoxide source in fast palladium-catalyzed aminocarbonylations of aryl bromides.
2002 Aug 23
Xanthamide fluorescent dyes.
2002 Dec 15
Comparison of the separation of large DNA fragments in the presence and absence of electroosmotic flow at high pH.
2002 Dec 6
Structure-reactivity relationships in the photoreduction of n,pi*-excited ketones and azoalkanes: the effect of reaction thermodynamics, excited-state electrophilicity, and antibonding character in the transition state.
2002 Feb
Deodorizing effects of tea catechins on amines and ammonia.
2002 Feb
Formation of N-nitrosodimethylamine (NDMA) from reaction of monochloramine: a new disinfection by-product.
2002 Feb
New sensitive and selective fluorescent probes for fluoride using boronic acids.
2002 Feb 1
1H NMR analysis for metabolites in serum and urine from rats administrated chronically with La(NO3)3.
2002 Feb 1
Kinetic studies of the binding of acridinecarboxamide topoisomerase poisons to DNA: implications for mode of binding of ligands with uncharged chromophores.
2002 Feb 14
Formation of N-nitrosodimethylamine (NDMA) from dimethylamine during chlorination.
2002 Feb 15
Synthesis of a new class of chiral 1,5-diphosphanylferrocene ligands and their use in enantioselective hydrogenation.
2002 Feb 15
[Biological and pathophysiological roles of endogenous methylarginines as inhibitors of nitric oxide synthase].
2002 Jan
Synthesis and biological activity of chiral tetrahydrofuranyl amino acids as building moieties of pamamycin analogues.
2002 Jan
Photophysics of 4-(N,N-dimethylamino)cinnamaldehyde/ alpha-cyclodextrin inclusion complex.
2002 Jan 1
Combined ab initio/empirical approach for optimization of Lennard-Jones parameters for polar-neutral compounds.
2002 Jan 30
A new procedure to produce lignocellulosic anion exchangers from agricultural waste materials.
2002 Jul
Volatile N-nitrosamine inhibition after intake Korean green tea and Maesil (Prunus mume SIEB. et ZACC.) extracts with an amine-rich diet in subjects ingesting nitrate.
2002 Jul
Aminoglycoside and glycopeptide renal toxicity in intensive care patients studied by proton magnetic resonance spectroscopy of urine.
2002 Jun
Helicobacter pylori does not mediate the formation of carcinogenic N-nitrosamines.
2002 Jun
Activities of therapeutic agents and myristamidopropyl dimethylamine against Acanthamoeba isolates.
2002 Jun
High-performance liquid chromatographic separation of carbohydrates on a stationary phase prepared from polystyrene-based resin and novel amines.
2002 Jun 28
Design, synthesis, and activity of a novel series of factor Xa inhibitors: optimization of arylamidine groups.
2002 Jun 6
Real-time, high-resolution quantitative measurement of multiple soil gas emissions: selected ion flow tube mass spectrometry.
2002 Mar-Apr
Structure--activity relationships of 1beta-methyl-2-(5-phenylpyrrolidin-3-ylthio)carbapenems.
2002 May
Enhanced activity of human N-myristoyltransferase by dimethyl sulfoxide and related solvents in the presence of serine/threonine-containing peptide substrates.
2002 Nov 15
Monitoring of headspace total volatile basic nitrogen from selected fish species using reflectance spectroscopic measurements of pH sensitive films.
2002 Oct
Identification and biochemical characterization of mutants in the proanthocyanidin pathway in Arabidopsis.
2002 Oct
Effects of pyridine ring substitutions on affinity, efficacy, and subtype selectivity of neuronal nicotinic receptor agonist epibatidine.
2002 Sep
Using trimethylamine dehydrogenase in an enzyme linked amperometric electrode. Part 1. Wild-type enzyme redox mediation.
2003 Feb
Is type 2 diabetes mellitus a vascular disease (atheroscleropathy) with hyperglycemia a late manifestation? The role of NOS, NO, and redox stress.
2003 Feb 12
Influence of the correlation, aggregation, and solvation on ab initio computed Li-C, Li-N, and Li-Li NMR coupling constants.
2003 Feb 21
Migration of methyl groups between aliphatic amines in water.
2003 Jan 15
Activation of 3-amino-1,2,4-benzotriazine 1,4-dioxide antitumor agents to oxidizing species following their one-electron reduction.
2003 Jan 22
Tuning the optical properties of fluorinated indolylfulgimides.
2003 Jan 24
Multistate/multifunctional systems. A thermodynamic, kinetic, and photochemical investigation of the 4'-dimethylaminoflavylium compound.
2003 Jan 29
Role of amination of a polymeric adsorbent on phenol adsorption from aqueous solution.
2003 Jun
Mesenteric microvascular inflammatory responses to systemic hypoxia are mediated by PAF and LTB4.
2003 Jun
5H-Dibenzo[c,h]1,6-naphthyridin-6-ones: novel topoisomerase I-targeting anticancer agents with potent cytotoxic activity.
2003 May 1
Patents
Substance Class Chemical
Created
by admin
on Mon Mar 31 18:01:44 GMT 2025
Edited
by admin
on Mon Mar 31 18:01:44 GMT 2025
Record UNII
ARQ8157E0Q
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
NSC-8650
Preferred Name English
Dimethylamine
HSDB   MI  
Systematic Name English
Metformin hydrochloride Impurity F [EP IMPURITY]
Common Name English
Dacarbazine Impurity D [EP IMPURITY]
Common Name English
Dimethylamine [MI]
Common Name English
N,N-Dimethylamine
Systematic Name English
N-Methylmethanamine
Systematic Name English
Dimethylamine [HSDB]
Common Name English
Code System Code Type Description
MESH
C034516
Created by admin on Mon Mar 31 18:01:44 GMT 2025 , Edited by admin on Mon Mar 31 18:01:44 GMT 2025
PRIMARY
NSC
8650
Created by admin on Mon Mar 31 18:01:44 GMT 2025 , Edited by admin on Mon Mar 31 18:01:44 GMT 2025
PRIMARY
ECHA (EC/EINECS)
204-697-4
Created by admin on Mon Mar 31 18:01:44 GMT 2025 , Edited by admin on Mon Mar 31 18:01:44 GMT 2025
PRIMARY
WIKIPEDIA
DIMETHYLAMINE
Created by admin on Mon Mar 31 18:01:44 GMT 2025 , Edited by admin on Mon Mar 31 18:01:44 GMT 2025
PRIMARY
CHEBI
58040
Created by admin on Mon Mar 31 18:01:44 GMT 2025 , Edited by admin on Mon Mar 31 18:01:44 GMT 2025
PRIMARY
CAS
124-40-3
Created by admin on Mon Mar 31 18:01:44 GMT 2025 , Edited by admin on Mon Mar 31 18:01:44 GMT 2025
PRIMARY
EPA CompTox
DTXSID5024057
Created by admin on Mon Mar 31 18:01:44 GMT 2025 , Edited by admin on Mon Mar 31 18:01:44 GMT 2025
PRIMARY
DAILYMED
ARQ8157E0Q
Created by admin on Mon Mar 31 18:01:44 GMT 2025 , Edited by admin on Mon Mar 31 18:01:44 GMT 2025
PRIMARY
HSDB
933
Created by admin on Mon Mar 31 18:01:44 GMT 2025 , Edited by admin on Mon Mar 31 18:01:44 GMT 2025
PRIMARY
FDA UNII
ARQ8157E0Q
Created by admin on Mon Mar 31 18:01:44 GMT 2025 , Edited by admin on Mon Mar 31 18:01:44 GMT 2025
PRIMARY
RXCUI
1745413
Created by admin on Mon Mar 31 18:01:44 GMT 2025 , Edited by admin on Mon Mar 31 18:01:44 GMT 2025
PRIMARY
CHEBI
17170
Created by admin on Mon Mar 31 18:01:44 GMT 2025 , Edited by admin on Mon Mar 31 18:01:44 GMT 2025
PRIMARY
PUBCHEM
674
Created by admin on Mon Mar 31 18:01:44 GMT 2025 , Edited by admin on Mon Mar 31 18:01:44 GMT 2025
PRIMARY
MERCK INDEX
m4520
Created by admin on Mon Mar 31 18:01:44 GMT 2025 , Edited by admin on Mon Mar 31 18:01:44 GMT 2025
PRIMARY Merck Index
Related Record Type Details
SALT/SOLVATE -> PARENT
PARENT -> CONSTITUENT ALWAYS PRESENT
Amine found in Acorus calamus rhizome.
LABELED -> NON-LABELED
SALT/SOLVATE -> PARENT
SALT/SOLVATE -> PARENT
Related Record Type Details
PARENT -> IMPURITY
UNSPECIFIED
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
PARENT -> IMPURITY