TYRPHOSTIN A46

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NCATS

Details

Stereochemistry	ACHIRAL
Molecular Formula	C10H8N2O3
Molecular Weight	204.1821
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	1
Charge	0

SHOW SMILES / InChI

Structure of TYRPHOSTIN A46

Structure Search

SMILES

NC(=O)C(=C\C1=CC(O)=C(O)C=C1)\C#N

InChI

InChIKey=USOXQZNJFMKTKJ-XVNBXDOJSA-N

InChI=1S/C10H8N2O3/c11-5-7(10(12)15)3-6-1-2-8(13)9(14)4-6/h1-4,13-14H,(H2,12,15)/b7-3+

HIDE SMILES / InChI

Molecular Formula	C10H8N2O3
Molecular Weight	204.1821
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	1
Optical Activity	NONE

Approval Year

Targets

Targets

Primary Target	Pharmacology	Condition	Potency
Epidermal growth factor receptor erbB1 62 Target ID: CHEMBL203 Sources: https://www.ncbi.nlm.nih.gov/pubmed/9516391	Inhibitor 8504		4.5 µM [IC50]

Substance Class	Chemical Created by `admin` on `Tue Apr 01 19:47:04 GMT 2025` Edited by `admin` on `Tue Apr 01 19:47:04 GMT 2025`
Record UNII	ARL2OF9022
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

NSC-666250

Preferred Name

English

TYRPHOSTIN A46

Common Name

English

AG 99 (ENZYME INHIBITOR)

Common Name

English

2-PROPENAMIDE, 2-CYANO-3-(3,4-DIHYDROXYPHENYL)-, (2E)-

Systematic Name

English

Classification Tree Code System Code

NCI_THESAURUS

C1757

Created by admin on Tue Apr 01 19:47:04 GMT 2025 , Edited by admin on Tue Apr 01 19:47:04 GMT 2025

Code System Code Type Description

NCI_THESAURUS

C1540

Created by admin on Tue Apr 01 19:47:04 GMT 2025 , Edited by admin on Tue Apr 01 19:47:04 GMT 2025

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CAS

122520-85-8

Created by admin on Tue Apr 01 19:47:04 GMT 2025 , Edited by admin on Tue Apr 01 19:47:04 GMT 2025

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NSC

666250

Created by admin on Tue Apr 01 19:47:04 GMT 2025 , Edited by admin on Tue Apr 01 19:47:04 GMT 2025

PRIMARY

FDA UNII

ARL2OF9022

Created by admin on Tue Apr 01 19:47:04 GMT 2025 , Edited by admin on Tue Apr 01 19:47:04 GMT 2025

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CAS

118409-59-9

Created by admin on Tue Apr 01 19:47:04 GMT 2025 , Edited by admin on Tue Apr 01 19:47:04 GMT 2025

NON-SPECIFIC STEREOCHEMISTRY

PUBCHEM

5328768

Created by admin on Tue Apr 01 19:47:04 GMT 2025 , Edited by admin on Tue Apr 01 19:47:04 GMT 2025

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