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Details

Stereochemistry ABSOLUTE
Molecular Formula C10H14N2O2S.ClH
Molecular Weight 262.756
Optical Activity UNSPECIFIED
Defined Stereocenters 2 / 2
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of AZD-9684 HYDROCHLORIDE

SMILES

Cl.C[C@@H](S)[C@@H](CC1=CN=C(N)C=C1)C(O)=O

InChI

InChIKey=AFSZUHJNOHISGY-CIRBGYJCSA-N
InChI=1S/C10H14N2O2S.ClH/c1-6(15)8(10(13)14)4-7-2-3-9(11)12-5-7;/h2-3,5-6,8,15H,4H2,1H3,(H2,11,12)(H,13,14);1H/t6-,8-;/m1./s1

HIDE SMILES / InChI

Molecular Formula ClH
Molecular Weight 36.461
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Molecular Formula C10H14N2O2S
Molecular Weight 226.295
Charge 0
Count
Stereochemistry ABSOLUTE
Additional Stereochemistry No
Defined Stereocenters 2 / 2
E/Z Centers 0
Optical Activity UNSPECIFIED

Approval Year

PubMed

PubMed

TitleDatePubMed
Laudanosine and atracurium concentrations in a patient receiving long-term atracurium infusion.
1998 Jan
Blockade and activation of the human neuronal nicotinic acetylcholine receptors by atracurium and laudanosine.
2001 Apr
Concentration-effect relationship of cisatracurium at three different dose levels in the anesthetized patient.
2001 Aug
Does ester hydrolysis change the in vitro degradation rate of cisatracurium and atracurium?
2002 Apr
Pharmacodynamics and atracurium and laudanosine concentrations during a fixed continuous infusion of atracurium in mechanically ventilated patients with acute respiratory distress syndrome.
2002 Aug
Colominic acid: a novel chiral selector for capillary electrophoresis of basic drugs.
2002 Jul 12
Cerebrospinal fluid concentrations of atracurium, laudanosine and vecuronium following clinical subarachnoid hemorrhage.
2002 Nov
Methyl-laudanosine: a new pharmacological tool to investigate the function of small-conductance Ca(2+)-activated K(+) channels.
2002 Sep
Aporphine alkaloids from Guatteria spp. with leishmanicidal activity.
2003 Jul
The GC-MS detection and characterization of reticuline as a marker of opium use.
2004 Mar 10
The efficient synthesis of morphinandienone alkaloids by using a combination of hypervalent iodine(III) reagent and heteropoly acid.
2004 Oct 11
Perinatal neuroprotection by muscle relaxants against hypoxic-ischemic lesions: is it a possible hypothesis?
2005 Aug
Evaluation of benzyltetrahydroisoquinolines as ligands for neuronal nicotinic acetylcholine receptors.
2005 Sep
Anesthesiologist suicide with atracurium.
2006 Mar
Simultaneous determination of atracurium and its metabolite laudanosine in post-mortem fluids by liquid chromatography/multiple-stage mass spectrometry on an ion trap.
2007
Bioactive constituents of the roots of Polyalthia cerasoides.
2007 Sep
[Absorption of papaverine, laudanosine and cepharanthine across human intestine by using human Caco-2 cells monolayers model].
2008 Feb
Synthesis of carbon-11 labeled 1-(3,4-dimethoxybenzyl)-2,2-dimethyl-1,2,3,4-tetrahydroisoquinolinium derivatives as new potential PET SKCa channel imaging agents.
2008 Feb
Use of intrathecal and intravenous clonidine in a case of severe tetanus with acute renal failure.
2009 Apr
Determination of atracurium, cisatracurium and mivacurium with their impurities in pharmaceutical preparations by liquid chromatography with charged aerosol detection.
2010 Feb 19
Evaluation of the enantioselectivity of glycogen-based dual chiral selector systems towards basic drugs in capillary electrophoresis.
2010 Nov 5
Substance Class Chemical
Created
by admin
on Sat Dec 16 12:12:51 GMT 2023
Edited
by admin
on Sat Dec 16 12:12:51 GMT 2023
Record UNII
AR85ERZ2P9
Record Status Validated (UNII)
Record Version
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Name Type Language
AZD-9684 HYDROCHLORIDE
Common Name English
(2S,3R)-2-((6-AMINO-3-PYRIDYL)METHYL)-3-SULFANYL-BUTANOIC ACID HYDROCHLORIDE
Systematic Name English
3-PYRIDINEPROPANOIC ACID, 6-AMINO-.ALPHA.-((1R)-1-MERCAPTOETHYL)-, HYDROCHLORIDE (1:1), (.ALPHA.S)-
Systematic Name English
AZD9684 HYDROCHLORIDE
Code English
Code System Code Type Description
CAS
305328-84-1
Created by admin on Sat Dec 16 12:12:51 GMT 2023 , Edited by admin on Sat Dec 16 12:12:51 GMT 2023
PRIMARY
FDA UNII
AR85ERZ2P9
Created by admin on Sat Dec 16 12:12:51 GMT 2023 , Edited by admin on Sat Dec 16 12:12:51 GMT 2023
PRIMARY
PUBCHEM
163203619
Created by admin on Sat Dec 16 12:12:51 GMT 2023 , Edited by admin on Sat Dec 16 12:12:51 GMT 2023
PRIMARY