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Details

Stereochemistry ABSOLUTE
Molecular Formula C29H38FN2O2.Br
Molecular Weight 545.527
Optical Activity UNSPECIFIED
Defined Stereocenters 2 / 2
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of AZD-9164 BROMIDE

SMILES

[Br-].C[C@@](N1CCCCC1)(C(=O)O[C@H]2C[N+]4(CCC3=CC=C(F)C=C3)CCC2CC4)C5=CC=CC=C5

InChI

InChIKey=QMMVAOGTOFQHAQ-BBCWMUSQSA-M
InChI=1S/C29H38FN2O2.BrH/c1-29(25-8-4-2-5-9-25,31-17-6-3-7-18-31)28(33)34-27-22-32(20-15-24(27)16-21-32)19-14-23-10-12-26(30)13-11-23;/h2,4-5,8-13,24,27H,3,6-7,14-22H2,1H3;1H/q+1;/p-1/t24?,27-,29-,32?;/m0./s1

HIDE SMILES / InChI
Molecular Formula BrH
Molecular Weight 80.912
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE
Molecular Formula C29H38FN2O2
Molecular Weight 465.6226
Charge 1
Count
Stereochemistry EPIMERIC
Additional Stereochemistry No
Defined Stereocenters 2 / 2
E/Z Centers 0
Optical Activity UNSPECIFIED

Description

AZD9164 was invented by AstraZeneca as a muscarinic M(3) receptor antagonist for evaluation of the potential as a treatment for chronic obstructive pulmonary disease. However, in 2010 studies were discontinued.

Originator

Approval Year

Unknown
139594
PubMed

PubMed

TitleDatePubMed
The discovery of AZD9164, a novel muscarinic M3 antagonist.
2011 Dec 15

Sample Use Guides

In Vivo Use Guide
Solution for inhalation through nebulization, single dose. AZD9164 solution for inhalation through nebulisation 100 mcg (lung deposited dose) + 1 x placebo for Spiriva dry powder for inhalation
Route of Administration: Other
Substance Class Chemical
Created
by admin
on Sat Dec 16 10:14:06 GMT 2023
Edited
by admin
on Sat Dec 16 10:14:06 GMT 2023
Record UNII
AQ25R8YQ5Z
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
AZD-9164 BROMIDE
Common Name English
1-AZONIABICYCLO(2.2.2)OCTANE, 1-(2-(4-FLUOROPHENYL)ETHYL)-3-((2S)-1-OXO-2-PHENYL-2-(1-PIPERIDINYL)PROPOXY)-, BROMIDE (1:1), (3R)-
Systematic Name English
AZD9164 BROMIDE
Code English
Code System Code Type Description
FDA UNII
AQ25R8YQ5Z
Created by admin on Sat Dec 16 10:14:06 GMT 2023 , Edited by admin on Sat Dec 16 10:14:06 GMT 2023
PRIMARY
CAS
1034916-72-7
Created by admin on Sat Dec 16 10:14:06 GMT 2023 , Edited by admin on Sat Dec 16 10:14:06 GMT 2023
PRIMARY
PUBCHEM
44553225
Created by admin on Sat Dec 16 10:14:06 GMT 2023 , Edited by admin on Sat Dec 16 10:14:06 GMT 2023
PRIMARY
Related Record Type Details
Structure of AZD-9164
PARENT -> SALT/SOLVATE
Related Record Type Details
Structure of AZD-9164
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