Cagrilintide

Investigational

Approval Year

Substance Class	Protein
Protein Type	PEPTIDE
Protein Sub Type	AMYLIN ANALOG
Sequence Origin	HUMAN
Sequence Type	COMPLETE
Record UNII	AO43BIF1U8
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

L-Prolinamide, N-(19-carboxy-1-oxononadecyl)-L-?-glutamyl-L-lysyl-L-cysteinyl-L-asparaginyl-L-threonyl-L-alanyl-L-threonyl-L-cysteinyl-L-alanyl-L-threonyl-L-glutaminyl-L-arginyl-L-leucyl-L-alanyl-L-?-glutamyl-L-phenylalanyl-L-leucyl-L-arginyl-L-histidyl-

Preferred Name

English

Cagrilintide

Official Name

English

CAGRILINTIDE [USAN]

Common Name

English

CagriSema component Cagrilintide

Common Name

English

cagrilintide [INN]

Common Name

English

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Code System

Code

Type

Description

CAS

1415456-99-3

PRIMARY

INN

11430

PRIMARY

USAN

LM-28

PRIMARY

NCI_THESAURUS

C175752

PRIMARY

FDA UNII

AO43BIF1U8

PRIMARY

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Subunit 0

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From	To
1_2	1_7

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Related Record

Type

Details


					U3U3114NE1

AMLINTIDE

TARGET->MIMETIC

Amount:

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Related Record

Type

Details


					AO43BIF1U8

Cagrilintide

ACTIVE MOIETY

Amount:

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Structural Modifications

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Modification Type	Location Site	Location Type	Residue Modified	Extent	Fragment Name	Fragment Approval
AMINO ACID SUBSTITUTION	[1_1]	N-TERMINUS	Lys		N-(19-carboxy-1-oxononadecyl)-L-?-glutamyl-L-lysine	XKP2SC88E6
AMINO ACID SUBSTITUTION	[1_37]	C-TERMINUS	Pro		PROLINAMIDE	VD6PQK9DHG

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Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
Molecular Formula	CHEMICAL	ESTIMATED C194H312O58N54S2
MOL_WEIGHT:NUMBER(CALCULATED)	CHEMICAL	EXACT 4409 Da (average)

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