DAFSOLIMAB

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Approval Year

Substance Class	Protein Created by `admin` on `Wed Apr 02 07:24:02 GMT 2025` Edited by `admin` on `Wed Apr 02 07:24:02 GMT 2025`
Protein Type	MONOCLONAL ANTIBODY
Protein Sub Type	IGG2B
Sequence Origin	MOUSE
Sequence Type	COMPLETE
Record UNII	AO2W2OFG8P
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

DAFSOLIMAB

Official Name

English

dafsolimab [INN]

Preferred Name

English

MMUNOGLOBULIN G2B-KAPPA, ANTI-(CD3E (CD3 EPSILON, LEU-4)), MUS MUSCULUS MONOCLONAL ANTIBODY (DAFSOLIMAB)

Common Name

English

IMMUNOGLOBULIN G2B, ANTI-(HUMAN CD3 ANTIGEN .EPSILON..DELTA. COMPLEX) (MUS MUSCULUS MONOCLONAL SPV-T3A .GAMMA.2B-CHAIN), DISULFIDE WITH MUS MUSCULUS MONOCLONAL SPV-T3A .KAPPA.-CHAIN, DIMER

Common Name

English

Code System Code Type Description

CAS

2367001-71-4

Created by admin on Wed Apr 02 07:24:02 GMT 2025 , Edited by admin on Wed Apr 02 07:24:02 GMT 2025

PRIMARY

SMS_ID

100000184304

Created by admin on Wed Apr 02 07:24:02 GMT 2025 , Edited by admin on Wed Apr 02 07:24:02 GMT 2025

PRIMARY

NCI_THESAURUS

C175760

Created by admin on Wed Apr 02 07:24:02 GMT 2025 , Edited by admin on Wed Apr 02 07:24:02 GMT 2025

PRIMARY

INN

11508

Created by admin on Wed Apr 02 07:24:02 GMT 2025 , Edited by admin on Wed Apr 02 07:24:02 GMT 2025

PRIMARY

FDA UNII

AO2W2OFG8P

Created by admin on Wed Apr 02 07:24:02 GMT 2025 , Edited by admin on Wed Apr 02 07:24:02 GMT 2025

PRIMARY

From	To
4_133	4_193
4_23	4_87
3_133	3_193
3_23	3_87
2_376	2_434
2_270	2_330
2_147	2_202
2_135	4_213
2_22	2_96
1_376	1_434
1_270	1_330
1_238	2_238
1_235	2_235
1_232	2_232
1_229	2_229
1_147	1_202
1_135	3_213
1_22	1_96

Glycosylation Link Type	Site
N	1_306
N	2_306

Related Record Type Details


					AG8ULI6K9U

DAFSOLIMAB SETARITOX

CONJUGATE -> PARENT

Amount:


					ZLW14X2D30

CD3

TARGET->LIGAND

Amount:

Structural Modifications

Modification Type	Location Site	Location Type	Residue Modified	Extent	Fragment Name	Fragment Approval
AMINO_ACID_SUBSTITUTION	[1_1] [2_1] [3_1] [4_1]	N-TERMINUS			PIDOLIC ACID	SZB83O1W42
AMINO ACID REMOVAL	[1_456] [2_456]	C-TERMINUS			LYSINE	K3Z4F929H6

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
Molecular Formula	CHEMICAL
MOL_WEIGHT:NUMBER(CALCULATED)	CHEMICAL