U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Approval Year

Substance Class Nucleic Acid
Created
by admin
on Sat Dec 16 18:56:46 GMT 2023
Edited
by admin
on Sat Dec 16 18:56:46 GMT 2023
Nucleic Acid Type OLIGONUCLEOTIDE
Nucleic Acid Subtype ANTI-SENSE
Sequence Type COMPLETE
Record UNII
AMW2VPZ3XD
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
LEXANERSEN
INN   USAN  
Official Name English
(P(S))-2'-O-METHYL-P-THIOGUANYLYL-(3'->5')-2'-O-METHYLURIDYLYL-(3'->5')-2'-O-METHYLGUANYLYL-(3'->5')-2'-O-METHYLCYTIDYLYL-(3'->5')-(P(S))-2'-O-METHYL-P-THIOADENYLYL-(3'->5')-(P(S))-2'-DEOXY-P-THIOCYTIDYLYL-(3'->5')-(P(S))-2'-DEOXY-P-THIOADENYLYL-(3'->5')
Common Name English
lexanersen [INN]
Common Name English
LEXANERSEN [USAN]
Common Name English
DNA, D(RGM-(P(S))-SP-RUM-RGM-RCM-RAM-(P(S))-SP-C-(P(S))-SP-A-(P(S))-SP-C-(P(S))-SP-A-(P(S))-SP-G-(P(S))-SP-T-(P(S))-SP-A-(P(S))-SP-G-(P(R))-SP-A-(P(S))-SP-T-(P(S))-SP-RGM-RAM-RGM-RGM-(P(S))-SP-RGM)
Common Name English
WV-2603 FREE ACID
Code English
BMTR5149 FREE ACID
Code English
WVE-120102 FREE ACID
Code English
BMTR-5149 FREE ACID
Code English
Code System Code Type Description
CAS
2073015-40-2
Created by admin on Sat Dec 16 18:56:46 GMT 2023 , Edited by admin on Sat Dec 16 18:56:46 GMT 2023
PRIMARY
FDA UNII
AMW2VPZ3XD
Created by admin on Sat Dec 16 18:56:46 GMT 2023 , Edited by admin on Sat Dec 16 18:56:46 GMT 2023
PRIMARY
USAN
GH-20
Created by admin on Sat Dec 16 18:56:46 GMT 2023 , Edited by admin on Sat Dec 16 18:56:46 GMT 2023
PRIMARY
NCI_THESAURUS
C180648
Created by admin on Sat Dec 16 18:56:46 GMT 2023 , Edited by admin on Sat Dec 16 18:56:46 GMT 2023
PRIMARY
INN
11353
Created by admin on Sat Dec 16 18:56:46 GMT 2023 , Edited by admin on Sat Dec 16 18:56:46 GMT 2023
PRIMARY
Sugar Site Range Site Count
Deoxyribose (DNA) 1_6-1_15 10 / 20
2'-O-Methyl-Ribose 1_1-1_5;1_16-1_20 10 / 20
Linkage Site Range Site Count
Phosphate 1_3-1_5;1_17-1_19 6 / 19
1_2;1_6-1_13;1_15-1_16;1_20 12 / 19
1_14 1 / 19
Related Record Type Details
SALT/SOLVATE -> PARENT
Related Record Type Details
ACTIVE MOIETY
WVE-120102 is designed to treat people with SNP2 (rs362331).