DELANTERONE

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C20H28O
Molecular Weight	284.4357
Optical Activity	UNSPECIFIED
Defined Stereocenters	6 / 6
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

[H][C@@]12CC=C[C@@]1(C)CC[C@@]3([H])[C@@]2([H])CCC4=CC(=O)C[C@H](C)[C@]34C

InChI

InChIKey=GDONNNQFENTLQC-VWTPSIDOSA-N

InChI=1S/C20H28O/c1-13-11-15(21)12-14-6-7-16-17-5-4-9-19(17,2)10-8-18(16)20(13,14)3/h4,9,12-13,16-18H,5-8,10-11H2,1-3H3/t13-,16-,17-,18-,19-,20-/m0/s1

HIDE SMILES / InChI

Molecular Formula	C20H28O
Molecular Weight	284.4357
Charge	0
Count

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	6 / 6
E/Z Centers	0
Optical Activity	UNSPECIFIED

Description
Sources: https://patents.google.com/patent/GB1550343

Delanterone is an antiandrogen steroid, developed by the Dutch company Gist-Brocades N.V. for the treatment of various dermatological disorders, including hirsutism, acne, seborrhea, alopecia androgenetica, and baldness. The compound is claimed to show topical anti-androgenic activity with very weak systemic anti-androgenic activity, a lack of progesterone, anti-gonadotrophin and corticosteroid-like activity and very low toxicity.

Originator

Approval Year

Patents

Substance Class	Chemical Created by `admin` on `Fri Dec 15 16:11:55 GMT 2023` Edited by `admin` on `Fri Dec 15 16:11:55 GMT 2023`
Record UNII	AM2KZ47R0J
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

DELANTERONE

Official Name

English

delanterone [INN]

Common Name

English

1.ALPHA.-METHYLANDROSTA-4,16-DIEN-3-ONE

Systematic Name

English

Classification Tree Code System Code

NCI_THESAURUS

C242