LYSINE, DL-

Details

Stereochemistry	RACEMIC
Molecular Formula	C6H14N2O2
Molecular Weight	146.1876
Optical Activity	( + / - )
Defined Stereocenters	0 / 1
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

NCCCCC(N)C(O)=O

InChI

InChIKey=KDXKERNSBIXSRK-UHFFFAOYSA-N

InChI=1S/C6H14N2O2/c7-4-2-1-3-5(8)6(9)10/h5H,1-4,7-8H2,(H,9,10)

HIDE SMILES / InChI

Molecular Formula	C6H14N2O2
Molecular Weight	146.1876
Charge	0
Count

Stereochemistry	RACEMIC
Additional Stereochemistry	No
Defined Stereocenters	0 / 1
E/Z Centers	0
Optical Activity	( + / - )

Approval Year

PubMed

Title	Date	PubMed
Mechanisms of biosynthesis of protein-derived redox cofactors.	2001	11153267
Optimization of experimental conditions for RNA-based sequencing of MLH1 and MSH2 genes.	2001	11139242
Mutational analysis of the MutH protein from Escherichia coli.	2001 Apr 13	11124943
Refolding and purification of Bothropstoxin-I, a Lys49-phospholipase A2 homologue, expressed as inclusion bodies in Escherichia coli.	2001 Feb	11162398
Irreversible block of human heart (hH1) sodium channels by the plant alkaloid lappaconitine.	2001 Feb	11160852
Glycoxidation and lipid peroxidation of low-density lipoprotein can synergistically enhance atherogenesis.	2001 Feb 1	11164857
Site-directed mutagenesis of human immunodeficiency virus type 1 reverse transcriptase at amino acid position 138.	2001 Feb 1	11162823
Selective inhibition of inducible nitric oxide synthase exacerbates erosive joint disease.	2001 Feb 15	11160339
A positively charged cluster formed in the heme-distal pocket of cytochrome P450nor is essential for interaction with NADH.	2001 Feb 16	11076941
Characterization of homo- and heterodimerization of cardiac Csx/Nkx2.5 homeoprotein.	2001 Feb 16	11042197
Identification of the main ubiquitination site in human erythroid alpha-spectrin.	2001 Feb 2	11165260
Two conserved lysines at the 50/20-kDa junction of myosin are necessary for triggering actin activation.	2001 Feb 2	11042210
Mutational analysis of protein substrate presentation in the post-translational attachment of biotin to biotin domains.	2001 Feb 2	11042165
A Role of RNA Helicase A in cis-Acting Transactivation Response Element-mediated Transcriptional Regulation of Human Immunodeficiency Virus Type 1.	2001 Feb 23	11096080
In vivo Hebbian and basal forebrain stimulation treatment in morphologically identified auditory cortical cells.	2001 Feb 9	11164811
Early glycation products produce pentosidine cross-links on native proteins. novel mechanism of pentosidine formation and propagation of glycation.	2001 Feb 9	11076948
Precursor supply for polyketide biosynthesis: the role of crotonyl-CoA reductase.	2001 Jan	11162231
A new h allele detected in Europe has a missense mutationin alpha(1,2)-fucosyltransferase motif II.	2001 Jan	11161242
Linear competitive inhibition of human tissue kallikrein by 4-aminobenzamidine and benzamidine and linear mixed inhibition by 4-nitroaniline and aniline.	2001 Jan	11151026
Lysostaphin expression in mammary glands confers protection against staphylococcal infection in transgenic mice.	2001 Jan	11135555
Abalone lysin: the dissolving and evolving sperm protein.	2001 Jan	11135314
The distinct disease phenotypes of the common and yellow vein strains of Tomato golden mosaic virus are determined by nucleotide differences in the 3'-terminal region of the gene encoding the movement protein.	2001 Jan	11125157
Intestinal apical amino acid absorption during development of the pig.	2001 Jan	11124157
Dimethyl 3,3'-dithiobispropionimidate: a novel crosslinking reagent for collagen.	2001 Jan	11077411
Tec kinase signaling in T cells is regulated by phosphatidylinositol 3-kinase and the Tec pleckstrin homology domain.	2001 Jan 1	11123316
Crystal structure of an enzyme-substrate complex provides insight into the interaction between human arylsulfatase A and its substrates during catalysis.	2001 Jan 12	11124905
Interference of biocytin with opioid-evoked hyperpolarization and membrane properties of rat spinal substantia gelatinosa neurons.	2001 Jan 12	11121884
Dissection of a nuclear localization signal.	2001 Jan 12	11038364
Sequence-specific DNA binding activity of RNA helicase A to the p16INK4a promoter.	2001 Jan 12	11038348
Mechanistic implications of mutations to the active site lysine of porphobilinogen synthase.	2001 Jan 12	11032841
Search for the autoantibody immunodominant region on thyroid peroxidase: epitopic footprinting with a human monoclonal autoantibody locates a facet on the native antigen containing a highly conformational epitope.	2001 Jan 15	11145717
Cloning and sequence of the LYS2 homologue gene from the osmotolerant yeast Pichia sorbitophila.	2001 Jan 15	11124702
Identification of lysine 346 as a functionally important residue for pyridoxal 5'-phosphate binding and catalysis in lysine 2, 3-aminomutase from Bacillus subtilis.	2001 Jan 16	11148055
Peptide models of the helical hydrophobic transmembrane segments of membrane proteins: interactions of acetyl-K2-(LA)12-K2-amide with phosphatidylethanolamine bilayer membranes.	2001 Jan 16	11148042
Interactions between yeast iso-1-cytochrome c and its peroxidase.	2001 Jan 16	11148036
Insights into the molecular basis for the carbenicillinase activity of PSE-4 beta-lactamase from crystallographic and kinetic studies.	2001 Jan 16	11148033
Short, solubilized polyalanines are conformational chameleons: exceptionally helical if N- and C-capped with helix stabilizers, weakly to moderately helical if capped with rigid spacers.	2001 Jan 16	11148022
The Lys1010-Lys1325 fragment of the Wilson's disease protein binds nucleotides and interacts with the N-terminal domain of this protein in a copper-dependent manner.	2001 Jan 19	11053407
Adaptive reversions of a frameshift mutation in arrested Saccharomyces cerevisiae cells by simple deletions in mononucleotide repeats.	2001 Jan 25	11166029
Mutations that affect ligand binding to the Escherichia coli aspartate receptor: implications for transmembrane signaling.	2001 Jan 26	11042221
Structural requirements for the stabilization of metarhodopsin II by the C terminus of the alpha subunit of transducin.	2001 Jan 26	11018024
Synthesis and evaluation of pteroic acid-conjugated nitroheterocyclic phosphoramidates as folate receptor-targeted alkylating agents.	2001 Jan 4	11141089
Acylation of lysine 983 is sufficient for toxin activity of Bordetella pertussis adenylate cyclase. Substitutions of alanine 140 modulate acylation site selectivity of the toxin acyltransferase CyaC.	2001 Jan 5	11031260
Purification, cloning, and characterization of a profibrinolytic plasminogen-binding protein, TIP49a.	2001 Jan 5	11027681
Local and long-range interactions in the thermal unfolding transition of bovine pancreatic ribonuclease A.	2001 Jan 9	11141060
Identification of the human mitochondrial oxodicarboxylate carrier. Bacterial expression, reconstitution, functional characterization, tissue distribution, and chromosomal location.	2001 Mar 16	11083877
Specific labeling of the bovine heart mitochondrial phosphate carrier with fluorescein 5-isothiocyanate: roles of Lys185 and putative adenine nucleotide recognition site in phosphate transport.	2001 Mar 30	11133984
Mutagenic analysis of functional residues in putative substrate-binding site and acidic domains of vacuolar H+-pyrophosphatase.	2001 Mar 9	11113147
Molecular mechanism for functional interaction between DnaA protein and acidic phospholipids: identification of important amino acids.	2001 Mar 9	11102450
Switching osmolyte strategies: response of Methanococcus thermolithotrophicus to changes in external NaCl.	2001 Nov 15	11078952

Patents

Substance Class	Chemical Created by `admin` on `Fri Dec 15 14:58:13 GMT 2023` Edited by `admin` on `Fri Dec 15 14:58:13 GMT 2023`
Record UNII	AI4RT59273
Record Status	`Validated (UNII)`
Record Version