METABOTROPIC GLUTAMATE RECEPTOR 1

Approval Year

Substance Class	Protein
Protein Type	RECEPTOR
Protein Sub Type
Sequence Origin	HUMAN
Sequence Type	COMPLETE
Record UNII	AI0R773C0C
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

METABOTROPIC GLUTAMATE RECEPTOR 1

Preferred Name

English

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Code System

Code

Type

Description

FDA UNII

AI0R773C0C

PRIMARY

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Subunit 0

Subunit 1

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From	To
1_49	1_91
1_271	1_273
1_360	1_376
1_414	1_421
1_639	1_728

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Glycosylation Type

HUMAN

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Glycosylation Link Type	Site
N	1_80
N	1_205
N	1_379
N	1_497
N	2_80

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Type

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LY-2428703 C-11

RADIOLIGAND->TARGET

Amount:


					N4LS35GV3Q

ETHYL N-(2,2-DIPHENYLACETYL)CARBAMATE

MODULATOR->TARGET

Interaction Type:

POSITIVE ALLOSTERIC MODULATOR

Amount:


					D7NM51C3GU

JBPOS-0101

INHIBITOR -> TARGET


					QM27L9Q3RZ

RO-67-4853

MODULATOR->TARGET

Interaction Type:

POSITIVE ALLOSTERIC MODULATOR

Amount:

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Structural Modifications

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Modification Type	Location Site	Location Type	Residue Modified	Extent	Fragment Name	Fragment Approval
AMINO ACID SUBSTITUTION	[1_835] [1_876] [1_951] [1_1073] [1_1124] [1_1131]
AMINO ACID SUBSTITUTION	[1_853] [1_1128]

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Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
MOL_WEIGHT	CHEMICAL

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