METABOTROPIC GLUTAMATE RECEPTOR 1

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Approval Year

Substance Class	Protein Created by `admin` on `Tue Apr 01 17:17:04 GMT 2025` Edited by `admin` on `Tue Apr 01 17:17:04 GMT 2025`
Protein Type	RECEPTOR
Protein Sub Type
Sequence Origin	HUMAN
Sequence Type	COMPLETE
Record UNII	AI0R773C0C
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

METABOTROPIC GLUTAMATE RECEPTOR 1

Preferred Name

English

Code System Code Type Description

FDA UNII

AI0R773C0C

Created by admin on Tue Apr 01 17:17:04 GMT 2025 , Edited by admin on Tue Apr 01 17:17:04 GMT 2025

PRIMARY

From	To
1_49	1_91
1_271	1_273
1_360	1_376
1_414	1_421
1_639	1_728
1_122	2_122
2_49	2_91
2_271	2_273
2_360	2_376
2_414	2_421
2_639	2_728

Glycosylation Type

HUMAN

Glycosylation Link Type	Site
N	1_80
N	1_205
N	1_379
N	1_497
N	2_80
N	2_205
N	2_379
N	2_497

Related Record Type Details


					46R067U4R3

LY-2428703 C-11

RADIOLIGAND->TARGET

Amount:


					N4LS35GV3Q

ETHYL N-(2,2-DIPHENYLACETYL)CARBAMATE

MODULATOR->TARGET

Interaction Type:

POSITIVE ALLOSTERIC MODULATOR

Amount:


					D7NM51C3GU

INHIBITOR -> TARGET


					QM27L9Q3RZ

MODULATOR->TARGET

Interaction Type:

POSITIVE ALLOSTERIC MODULATOR

Amount:

Structural Modifications

Modification Type	Location Site	Location Type	Residue Modified	Extent	Fragment Name	Fragment Approval
AMINO ACID SUBSTITUTION	[1_835] [1_876] [1_951] [1_1073] [1_1124] [1_1131]
AMINO ACID SUBSTITUTION	[1_853] [1_1128]

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
MOL_WEIGHT	CHEMICAL