Efsudenermin Alfa

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Investigational

Investigational

Approval Year

Substance Class	Protein Created by `admin` on `Wed Apr 02 21:10:07 GMT 2025` Edited by `admin` on `Wed Apr 02 21:10:07 GMT 2025`
Protein Type	FC FUSION PROTEIN
Protein Sub Type	TNF BINDER
Sequence Origin	HUMAN
Sequence Type	COMPLETE
Record UNII	AF6GZK1UMB
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

Efsudenermin Alfa

Official Name

English

APO200

Preferred Name

English

EDI-200

Code

English

HUMAN IMMUNOGLOBULIN G1 CONSTANT REGION - HUMAN ECTODYSPLASIN-A1 RECEPTOR-BINDING DOMAIN FUSION PROTEIN

Common Name

English

Immunoglobulin G1 (human ?1-chain C region C-terminal fragment) fusion protein with 238-391-ectodysplasin-A (human), hexamer

Common Name

English

FC:EDA-A1 FUSION PROTEIN

Common Name

English

EDI200

Code

English

efsudenermin alfa [INN]

Common Name

English

Fc fragment of human immunoglobulin G1 (1-226) [Homo sapiens IGHG1*01, (1-9), CH2 (10-119), CH3 (120-224), CHS (225-226)] fused to human ectodysplasin-A (ectodermal dysplasia protein, EDA protein, ED1) fragment (238-391, 227-380 in the current sequence),

Common Name

English

Classification Tree Code System Code

FDA ORPHAN DRUG

216005

Created by admin on Wed Apr 02 21:10:07 GMT 2025 , Edited by admin on Wed Apr 02 21:10:07 GMT 2025

EU-Orphan Drug

EU/3/05/334

Created by admin on Wed Apr 02 21:10:07 GMT 2025 , Edited by admin on Wed Apr 02 21:10:07 GMT 2025

Code System Code Type Description

FDA UNII

AF6GZK1UMB

Created by admin on Wed Apr 02 21:10:07 GMT 2025 , Edited by admin on Wed Apr 02 21:10:07 GMT 2025

PRIMARY

INN

13227

Created by admin on Wed Apr 02 21:10:07 GMT 2025 , Edited by admin on Wed Apr 02 21:10:07 GMT 2025

PRIMARY

CAS

2769701-94-0

Created by admin on Wed Apr 02 21:10:07 GMT 2025 , Edited by admin on Wed Apr 02 21:10:07 GMT 2025

PRIMARY

NCI_THESAURUS

C211755

Created by admin on Wed Apr 02 21:10:07 GMT 2025 , Edited by admin on Wed Apr 02 21:10:07 GMT 2025

PRIMARY

SMS_ID

100000182582

Created by admin on Wed Apr 02 21:10:07 GMT 2025 , Edited by admin on Wed Apr 02 21:10:07 GMT 2025

PRIMARY

From	To
1_321	1_335
6_321	6_335
5_321	5_335
4_321	4_335
3_321	3_335
1_146	1_204
6_146	6_204
5_146	5_204
4_146	4_204
3_146	3_204
1_40	1_100
6_40	6_100
5_40	5_100
4_40	4_100
3_40	3_100

Glycosylation Type

MAMMALIAN

Glycosylation Link Type	Site
N	1_76
N	1_302
N	1_361
N	2_76
N	2_302
N	2_361
N	3_76
N	3_302
N	3_361
N	4_76
N	4_302
N	4_361
N	5_76
N	5_302
N	5_361
N	6_76
N	6_302
N	6_361

Related Record Type Details


					4TVX2I407K

TUMOR NECROSIS FACTOR-.ALPHA. HUMAN (PLASMA DERIVED, SOLUBLE FORM)

TARGET -> INHIBITOR

Amount:

Related Record Type Details


					AF6GZK1UMB

Efsudenermin Alfa

ACTIVE MOIETY

Amount:

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
MOL_WEIGHT:NUMBER(CALCULATED)	CHEMICAL
Molecular Formula	CHEMICAL