Details
| Stereochemistry | RACEMIC |
| Molecular Formula | C3H5ClO2 |
| Molecular Weight | 108.524 |
| Optical Activity | ( + / - ) |
| Defined Stereocenters | 0 / 1 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
CC(Cl)C(O)=O
InChI
InChIKey=GAWAYYRQGQZKCR-UHFFFAOYSA-N
InChI=1S/C3H5ClO2/c1-2(4)3(5)6/h2H,1H3,(H,5,6)
| Molecular Formula | C3H5ClO2 |
| Molecular Weight | 108.524 |
| Charge | 0 |
| Count |
|
| Stereochemistry | RACEMIC |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 1 |
| E/Z Centers | 0 |
| Optical Activity | ( + / - ) |
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Initial biological qualification of SBDP-145 as a biomarker of compound-induced neurodegeneration in the rat. | 2014-10 |
|
| Role of pyruvate dehydrogenase kinase 4 in regulation of blood glucose levels. | 2010-10 |
|
| Clinical physiology and mechanism of dizocilpine (MK-801): electron transfer, radicals, redox metabolites and bioactivity. | 2010-08-19 |
|
| Metal-catalyzed simultaneous chain- and step-growth radical polymerization: marriage of vinyl polymers and polyesters. | 2010-06-02 |
|
| Roles of K151 and D180 in L-2-haloacid dehalogenase from Pseudomonas sp. YL: analysis by molecular dynamics and ab initio fragment molecular orbital calculations. | 2009-12 |
|
| Direct determination of the enantiomeric purity or enantiomeric composition of methylpropionates using a single capacitive microsensor. | 2009-03-01 |
|
| Methyl 2-(N-methoxy-carbonyl-meth-yl-N-methylsulfamo-yl)benzoate. | 2009-02-04 |
|
| Isolation of a bacterium possessing a haloacid dehalogenase from a marine sediment core. | 2009 |
|
| Tuning the chiral cavity of macrocyclic receptor for chiral recognition and discrimination. | 2008-11-21 |
|
| Production of (S)-2-chloropropionate by asymmetric reduction of 2-chloroacrylate with 2-haloacrylate reductase coupled with glucose dehydrogenase. | 2008-04 |
|
| Crystal structures of the substrate free-enzyme, and reaction intermediate of the HAD superfamily member, haloacid dehalogenase DehIVa from Burkholderia cepacia MBA4. | 2007-05-04 |
|
| (+/-)-2-Chloropropionic acid elevates reactive oxygen species formation in human neutrophil granulocytes. | 2006-12-07 |
|
| Mechanism of the reaction catalyzed by DL-2-haloacid dehalogenase as determined from kinetic isotope effects. | 2006-05-16 |
|
| Thermoresponsive comb-shaped copolymer-Si(100) hybrids for accelerated temperature-dependent cell detachment. | 2006-03 |
|
| Copper(II)-mediated resolution of alpha-halo carboxylic acids with chiral O,O'-dibenzoyltartaric acid: spontaneous racemization and crystallization-induced dynamic resolution. | 2005-12-07 |
|
| Biochemical and molecular characterisation of the 2,3-dichloro-1-propanol dehalogenase and stereospecific haloalkanoic dehalogenases from a versatile Agrobacterium sp. | 2005-10 |
|
| Synthesis of a peroxime proliferator activated receptor (PPAR) alpha/gamma agonist via stereocontrolled Williamson ether synthesis and stereospecific SN2 reaction of S-2-chloro propionic acid with phenoxides. | 2005-06-10 |
|
| 2-Haloacrylate reductase, a novel enzyme of the medium chain dehydrogenase/reductase superfamily that catalyzes the reduction of a carbon-carbon double bond of unsaturated organohalogen compounds. | 2005-05-27 |
|
| Synthesis of PPAR agonist via asymmetric hydrogenation of a cinnamic acid derivative and stereospecific displacement of (S)-2-chloropropionic acid. | 2005-05-12 |
|
| Purification, crystallization and preliminary crystallographic analysis of DehIVa, a dehalogenase from Burkholderia cepacia MBA4. | 2005-03-01 |
|
| Re-evaluation of archival material for neuronal cell injury produced by L-2-chloropropionic acid in the rat brain. | 2004-12 |
|
| Genetic organization of the dhlA gene encoding 1,2-dichloroethane dechlorinase from Xanthobacter flavus UE15. | 2004-09 |
|
| Putrescine as a marker of the effects of 2-chloropropionic acid in the rat brain. | 2004-05-27 |
|
| Horizontal transfer of dehalogenase genes on IncP1beta plasmids during bacterial adaptation to degrade alpha-halocarboxylic acids. | 2003-08-01 |
|
| Impaired mitochondrial pyruvate importation in a patient and a fetus at risk. | 2003-03 |
|
| Photoreduction of the chloropropionic acid of carfentrazone-ethyl in sodium sulfide [corrected]. | 2002-10 |
|
| Modification of the enantioselectivity of two homologous thermophilic carboxylesterases from Alicyclobacillus acidocaldarius and Archaeoglobus fulgidus by random mutagenesis and screening. | 2002-08 |
|
| Stereoselective synthesis of Psi[CH(2)O] pseudodipeptides and conformational analysis of a PhePsi[CH(2)O]Ala containing analogue of the drug desmopressin. | 2002-03-25 |
|
| Whole-cell biodetection of halogenated organic acids. | 2001-12-13 |
|
| Toxic effect of L-2-chloropropionate on cultured rat cerebellar granule cells is ameliorated after inhibition of reactive oxygen species formation. | 2001-12-01 |
|
| MRI studies of the neurotoxic effects of L-2-chloropropionic acid on rat brain. | 2001-02 |
|
| The effect of postnatal age on L-2-chloropropionic acid-induced cerebellar granule cell necrosis in the rat. | 2001-02 |
|
| Neuroprotective effects of MK-801 on L-2-chloropropionic acid-induced neurotoxicity. | 2001-02 |
|
| Use of structure-activity relationships for probing biochemical mechanisms: glutathione transferase zeta conjugation of haloacids. | 2001 |
|
| L-2-chloropropionic acid-induced cerebellar granule cell necrosis is potentiated by L-type calcium channel antagonists. | 1997 |
Patents
| Substance Class |
Chemical
Created
by
admin
on
Edited
Mon Mar 31 20:52:09 GMT 2025
by
admin
on
Mon Mar 31 20:52:09 GMT 2025
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| Record UNII |
ADV1WUE1NB
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| Record Status |
Validated (UNII)
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| Record Version |
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2-CHLOROPROPIONIC ACID
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C021974
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209-952-3
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ADV1WUE1NB
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DTXSID0021545
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173
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11734
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5713
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598-78-7
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