U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Approval Year

Substance Class Protein
Created
by admin
on Sat Dec 16 13:40:18 GMT 2023
Edited
by admin
on Sat Dec 16 13:40:18 GMT 2023
Protein Type ENZYME
Protein Sub Type GLYCOSIDASE
Sequence Origin HUMAN
Sequence Type COMPLETE
Record UNII
AA60A4ST8X
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
TRALESINIDASE ALFA
INN  
Official Name English
.ALPHA.-N-ACETYLGLUCOSAMINIDASE (HUMAN) FUSION PROTEIN WITH PEPTIDE (SYNTHETIC LINKER) FUSION PROTEIN WITH INSULIN-LIKE GROWTH FACTOR II (HUMAN FRAGMENT)
Common Name English
NAGLU-IGF2 FUSION PROTEIN
Common Name English
ALPHA-N-ACETYGLUCOSAMINIDASE-INSULIN-LIKE-GROWTH-FACTOR-2 FUSION PROTEIN
Common Name English
tralesinidase alfa [INN]
Common Name English
BMN-250
Code English
BMN250
Code English
Tralesinidase alfa [WHO-DD]
Common Name English
Classification Tree Code System Code
FDA ORPHAN DRUG 388712
Created by admin on Sat Dec 16 13:40:18 GMT 2023 , Edited by admin on Sat Dec 16 13:40:18 GMT 2023
FDA ORPHAN DRUG 450014
Created by admin on Sat Dec 16 13:40:18 GMT 2023 , Edited by admin on Sat Dec 16 13:40:18 GMT 2023
NCI_THESAURUS C29726
Created by admin on Sat Dec 16 13:40:18 GMT 2023 , Edited by admin on Sat Dec 16 13:40:18 GMT 2023
Code System Code Type Description
INN
10464
Created by admin on Sat Dec 16 13:40:18 GMT 2023 , Edited by admin on Sat Dec 16 13:40:18 GMT 2023
PRIMARY
CAS
1808916-28-0
Created by admin on Sat Dec 16 13:40:18 GMT 2023 , Edited by admin on Sat Dec 16 13:40:18 GMT 2023
PRIMARY
NCI_THESAURUS
C152709
Created by admin on Sat Dec 16 13:40:18 GMT 2023 , Edited by admin on Sat Dec 16 13:40:18 GMT 2023
PRIMARY
FDA UNII
AA60A4ST8X
Created by admin on Sat Dec 16 13:40:18 GMT 2023 , Edited by admin on Sat Dec 16 13:40:18 GMT 2023
PRIMARY
From To
1_74 1_76
1_250 1_254
1_481 1_486
1_753 1_791
1_765 1_804
1_790 1_795
Glycosylation Type MAMMALIAN
Glycosylation Link Type Site
N 1_238
N 1_249
N 1_412
N 1_480
N 1_490
N 1_503
N 1_509
O 1_727
O 1_733
O 1_739
O 1_748
Related Record Type Details
TARGET->ENZYME REPLACEMENT
ALPHA-N-ACETYLGLUCOSAMINIDASE 82 KDA FORM
Related Record Type Details
ACTIVE MOIETY
Name Property Type Amount Referenced Substance Defining Parameters References
MOL_WEIGHT:NUMBER(CALCULATED) CHEMICAL
Molecular Formula CHEMICAL