TRALESINIDASE ALFA

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Investigational

Approval Year

Substance Class	Protein Created by `admin` on `Tue Apr 01 21:05:53 GMT 2025` Edited by `admin` on `Tue Apr 01 21:05:53 GMT 2025`
Protein Type	ENZYME
Protein Sub Type	GLYCOSIDASE
Sequence Origin	HUMAN
Sequence Type	COMPLETE
Record UNII	AA60A4ST8X
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

BMN-250

Preferred Name

English

TRALESINIDASE ALFA

Official Name

English

.ALPHA.-N-ACETYLGLUCOSAMINIDASE (HUMAN) FUSION PROTEIN WITH PEPTIDE (SYNTHETIC LINKER) FUSION PROTEIN WITH INSULIN-LIKE GROWTH FACTOR II (HUMAN FRAGMENT)

Common Name

English

NAGLU-IGF2 FUSION PROTEIN

Common Name

English

ALPHA-N-ACETYGLUCOSAMINIDASE-INSULIN-LIKE-GROWTH-FACTOR-2 FUSION PROTEIN

Common Name

English

tralesinidase alfa [INN]

Common Name

English

BMN250

Code

English

Tralesinidase alfa [WHO-DD]

Common Name

English

Classification Tree Code System Code

FDA ORPHAN DRUG

388712

Created by admin on Tue Apr 01 21:05:53 GMT 2025 , Edited by admin on Tue Apr 01 21:05:53 GMT 2025

FDA ORPHAN DRUG

450014

Created by admin on Tue Apr 01 21:05:53 GMT 2025 , Edited by admin on Tue Apr 01 21:05:53 GMT 2025

NCI_THESAURUS

C29726

Created by admin on Tue Apr 01 21:05:53 GMT 2025 , Edited by admin on Tue Apr 01 21:05:53 GMT 2025

Code System Code Type Description

INN

10464

Created by admin on Tue Apr 01 21:05:53 GMT 2025 , Edited by admin on Tue Apr 01 21:05:53 GMT 2025

PRIMARY

SMS_ID

100000178253

Created by admin on Tue Apr 01 21:05:53 GMT 2025 , Edited by admin on Tue Apr 01 21:05:53 GMT 2025

PRIMARY

CAS

1808916-28-0

Created by admin on Tue Apr 01 21:05:53 GMT 2025 , Edited by admin on Tue Apr 01 21:05:53 GMT 2025

PRIMARY

NCI_THESAURUS

C152709

Created by admin on Tue Apr 01 21:05:53 GMT 2025 , Edited by admin on Tue Apr 01 21:05:53 GMT 2025

PRIMARY

FDA UNII

AA60A4ST8X

Created by admin on Tue Apr 01 21:05:53 GMT 2025 , Edited by admin on Tue Apr 01 21:05:53 GMT 2025

PRIMARY

From	To
1_74	1_76
1_250	1_254
1_481	1_486
1_753	1_791
1_765	1_804
1_790	1_795

Glycosylation Type

MAMMALIAN

Glycosylation Link Type	Site
N	1_238
N	1_249
N	1_412
N	1_480
N	1_490
N	1_503
N	1_509
O	1_727
O	1_733
O	1_739
O	1_748

Related Record Type Details


					6LSD2TC5Y6

ALPHA-N-ACETYLGLUCOSAMINIDASE 82 KDA FORM

TARGET->ENZYME REPLACEMENT

Comments:

ALPHA-N-ACETYLGLUCOSAMINIDASE 82 KDA FORM

Related Record Type Details


					AA60A4ST8X

TRALESINIDASE ALFA

ACTIVE MOIETY

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
MOL_WEIGHT:NUMBER(CALCULATED)	CHEMICAL
Molecular Formula	CHEMICAL