PF-06409577

OC(=O)C1=CNC2=CC(Cl)=C(C=C12)C3=CC=C(C=C3)C4(O)CCC4

InChIKey=FHQXLWCFSUSXBF-UHFFFAOYSA-N

InChI=1S/C19H16ClNO3/c20-16-9-17-14(15(10-21-17)18(22)23)8-13(16)11-2-4-12(5-3-11)19(24)6-1-7-19/h2-5,8-10,21,24H,1,6-7H2,(H,22,23)

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Targets

Primary Target	Pharmacology	Condition	Potency
AMP-activated protein kinase (AMPK) alpha-1/beta-1/gamma-1 4 Target ID: CHEMBL2111345 Sources: https://www.ncbi.nlm.nih.gov/pubmed/27490827	Activator 1430		7.0 nM [EC50]

Substance Class	Chemical Created by `admin` on `Sat Dec 16 18:11:40 GMT 2023` Edited by `admin` on `Sat Dec 16 18:11:40 GMT 2023`
Record UNII	A89WAM8FBH
Record Status	`Validated (UNII)`
Record Version

Name

Type

Language

PF-06409577

Code

English

6-CHLORO-5-(4-(1-HYDROXYCYCLOBUTYL)PHENYL)-1H-INDOLE-3-CARBOXYLIC ACID

Systematic Name

English

1H-INDOLE-3-CARBOXYLIC ACID, 6-CHLORO-5-(4-(1-HYDROXYCYCLOBUTYL)PHENYL)-

Systematic Name

English

Code System Code Type Description

PUBCHEM

71748255

Created by admin on Sat Dec 16 18:11:40 GMT 2023 , Edited by admin on Sat Dec 16 18:11:40 GMT 2023

PRIMARY

FDA UNII

A89WAM8FBH

Created by admin on Sat Dec 16 18:11:40 GMT 2023 , Edited by admin on Sat Dec 16 18:11:40 GMT 2023

PRIMARY

CAS

1467057-23-3

Created by admin on Sat Dec 16 18:11:40 GMT 2023 , Edited by admin on Sat Dec 16 18:11:40 GMT 2023

PRIMARY

Related Record Type Details


					A89WAM8FBH

ACTIVE MOIETY

Amount: