ESAFLOXACIN

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	RACEMIC
Molecular Formula	C15H17FN4O3
Molecular Weight	320.3189
Optical Activity	( + / - )
Defined Stereocenters	0 / 1
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of ESAFLOXACIN

Structure Search

SMILES

CCN1C=C(C(O)=O)C(=O)C2=C1N=C(N3CCC(N)C3)C(F)=C2

InChI

InChIKey=BQDVLIDLHOSQHC-UHFFFAOYSA-N

InChI=1S/C15H17FN4O3/c1-2-19-7-10(15(22)23)12(21)9-5-11(16)14(18-13(9)19)20-4-3-8(17)6-20/h5,7-8H,2-4,6,17H2,1H3,(H,22,23)

HIDE SMILES / InChI

Molecular Formula	C15H17FN4O3
Molecular Weight	320.3189
Charge	0
Count

Stereochemistry	RACEMIC
Additional Stereochemistry	No
Defined Stereocenters	0 / 1
E/Z Centers	0
Optical Activity	( + / - )

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/6438319 | https://link.springer.com/chapter/10.1007%2F978-1-4757-2085-3_5

Esafloxacin (7-(3-amino-1-pyrrolidinyl)-1-ethyl-6-fluoro-1,4 -dihydro-4-oxo-1,8-naphthyridine-3-carboxylic acid) is an antibacterial agent.

Originator

Approval Year

PubMed

PubMed

Title	Date	PubMed
Pyridonecarboxylic acids as antibacterial agents. 4. Synthesis and antibacterial activity of 7-(3-amino-1-pyrrolidinyl)-1-ethyl-6-fluoro-1,4 -dihydro-4-oxo-1,8-naphthyridine-3-carboxylic acid and its analogues.	1984 Dec	6438319

Substance Class	Chemical Created by `admin` on `Fri Dec 15 16:28:42 GMT 2023` Edited by `admin` on `Fri Dec 15 16:28:42 GMT 2023`
Record UNII	A6NT0I9X0K
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

ESAFLOXACIN

Official Name

English

(±)-7-(3-AMINO-1-PYRROLIDINYL)-1-ETHYL-6-FLUORO-1,4-DIHYDRO-4-OXO-1,8-NAPHTHYRIDINE-3-CARBOXYLIC ACID

Systematic Name

English

esafloxacin [INN]

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C795

Created by admin on Fri Dec 15 16:28:42 GMT 2023 , Edited by admin on Fri Dec 15 16:28:42 GMT 2023

Code System Code Type Description

CAS

79286-77-4

Created by admin on Fri Dec 15 16:28:42 GMT 2023 , Edited by admin on Fri Dec 15 16:28:42 GMT 2023

PRIMARY

NCI_THESAURUS

C65534

Created by admin on Fri Dec 15 16:28:42 GMT 2023 , Edited by admin on Fri Dec 15 16:28:42 GMT 2023

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EVMPD

SUB06606MIG

Created by admin on Fri Dec 15 16:28:42 GMT 2023 , Edited by admin on Fri Dec 15 16:28:42 GMT 2023

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FDA UNII

A6NT0I9X0K

Created by admin on Fri Dec 15 16:28:42 GMT 2023 , Edited by admin on Fri Dec 15 16:28:42 GMT 2023

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INN

6333

Created by admin on Fri Dec 15 16:28:42 GMT 2023 , Edited by admin on Fri Dec 15 16:28:42 GMT 2023

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PUBCHEM

208933

Created by admin on Fri Dec 15 16:28:42 GMT 2023 , Edited by admin on Fri Dec 15 16:28:42 GMT 2023

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SMS_ID

100000084563

Created by admin on Fri Dec 15 16:28:42 GMT 2023 , Edited by admin on Fri Dec 15 16:28:42 GMT 2023

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ChEMBL

CHEMBL37683

Created by admin on Fri Dec 15 16:28:42 GMT 2023 , Edited by admin on Fri Dec 15 16:28:42 GMT 2023

PRIMARY

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