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Details

Stereochemistry ACHIRAL
Molecular Formula C4H11NO.ClH
Molecular Weight 125.597
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of DEANOL HYDROCHLORIDE

SMILES

Cl.CN(C)CCO

InChI

InChIKey=YJHSJERLYWNLQL-UHFFFAOYSA-N
InChI=1S/C4H11NO.ClH/c1-5(2)3-4-6;/h6H,3-4H2,1-2H3;1H

HIDE SMILES / InChI

Molecular Formula C4H11NO
Molecular Weight 89.1362
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Molecular Formula ClH
Molecular Weight 36.461
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

DEANOL is an inactive component of CERAVE® hydrocortisone anti-itch cream, which is used for temporarily relieve itching associated with minor skin irritations, inflammation, and rashes due to eczema, soaps, detergents, cosmetics, seborrheic dermatitis, psoriasis. DEANOL is also used as a food additive.

Approval Year

Doses

Doses

DosePopulationAdverse events​
0.1 % single, topical
Highest studied dose
healthy
6000 mg 1 times / day multiple, oral
Highest studied dose
Dose: 6000 mg, 1 times / day
Route: oral
Route: multiple
Dose: 6000 mg, 1 times / day
Sources: Page: p.188
unhealthy
Health Status: unhealthy
Condition: Involuntary movement disorders
Sources: Page: p.188
Sourcing

Sourcing

Vendor/AggregatorIDURL
PubMed

PubMed

TitleDatePubMed
The relationship between the interfacial properties of surfactants and their toxicity to aquatic organisms.
2001 Mar 1
Perturbations in choline metabolism cause neural tube defects in mouse embryos in vitro.
2002 Apr
Split face study on the cutaneous tensile effect of 2-dimethylaminoethanol (deanol) gel.
2002 Aug
Preparation of phytate-removed deamidated soybean globulins by ion exchangers and characterization of their calcium-binding ability.
2002 Jan 2
Studies of the side chain cleavage of deramciclane in rats with radiolabelled compounds.
2002 Mar
Water-soluble biodegradable cationic polyphosphazenes for gene delivery.
2003 May 20
Copper (II)-mediated arylation with aryl boronic acids for the N-derivatization of pyrazole libraries.
2004 May-Jun
[Fluorescent-labeled lipophilic analogues of serotonin, dopamine, and acetylcholine: synthesis, mass spectrometry, and biological activity].
2004 Sep-Oct
The evolution of senescence and post-reproductive lifespan in guppies (Poecilia reticulata).
2006 Jan
Dimethylaminoethanol affects the viability of human cultured fibroblasts.
2007 Nov-Dec
Fully automated [18F]fluorocholine synthesis in the TracerLab MX FDG Coincidence synthesizer.
2008 Feb
Experimental and theoretical investigation into the correlation between mass and ion mobility for choline and other ammonium cations in N2.
2008 Mar 15
Bis[N-(2-hydroxy-ethyl)-N-methyl-glycinato]copper(II).
2008 Nov 22
In vivo skin effects of a dimethylaminoethanol (DMAE) based formulation.
2009 Dec
The pentameric vertex proteins are necessary for the icosahedral carboxysome shell to function as a CO2 leakage barrier.
2009 Oct 21
Mesotherapy - The french connection.
2010 Jan
Structural characterization and stability of dimethylaminoethanol and dimethylaminoethanol bitartrate for possible use in cosmetic firming.
2010 Jul-Aug
The choC gene encoding a putative phospholipid methyltransferase is essential for growth and development in Aspergillus nidulans.
2010 Jun
Chloridotris[μ(2)-2-(dimethyl-amino)-ethano-lato]-μ(3)-hydroxido-tri-μ(2)-trifluoro-acetato-tetra-copper(II) tetra-hydro-furan solvate.
2010 Jun 18
In vitro cytotoxicity of benzopyranone derivatives with basic side chain against human lung cell lines.
2010 Nov
Release of DNA from polyelectrolyte multilayers fabricated using 'charge-shifting' cationic polymers: tunable temporal control and sequential, multi-agent release.
2010 Nov 20
Novel pathway to synthesize unsymmetrical 2,3,9,10,16,17,23-heptakis(alkoxyl)-24-mono(dimethylaminoalkoxyl)phthalocyanines.
2010 Oct 4
Patents
Substance Class Chemical
Created
by admin
on Sat Dec 16 02:16:42 GMT 2023
Edited
by admin
on Sat Dec 16 02:16:42 GMT 2023
Record UNII
A6A0TB3ES3
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
DEANOL HYDROCHLORIDE
Common Name English
2-(DIMETHYLAMINO)ETHANOL HYDROCHLORIDE
Systematic Name English
ETHANOL, 2-(DIMETHYLAMINO)-, HYDROCHLORIDE (1:1)
Systematic Name English
ETHANOL, 2-DIMETHYLAMINO-, HYDROCHLORIDE
Systematic Name English
2-DIETHYLAMINOETHANOL HYDROCHLORIDE
Systematic Name English
2-(N,N-DIMETHYLAMINO)ETHANOL HYDROCHLORIDE
Systematic Name English
Code System Code Type Description
CAS
2498-25-1
Created by admin on Sat Dec 16 02:16:42 GMT 2023 , Edited by admin on Sat Dec 16 02:16:42 GMT 2023
PRIMARY
EPA CompTox
DTXSID30179692
Created by admin on Sat Dec 16 02:16:42 GMT 2023 , Edited by admin on Sat Dec 16 02:16:42 GMT 2023
PRIMARY
PUBCHEM
200674
Created by admin on Sat Dec 16 02:16:42 GMT 2023 , Edited by admin on Sat Dec 16 02:16:42 GMT 2023
PRIMARY
FDA UNII
A6A0TB3ES3
Created by admin on Sat Dec 16 02:16:42 GMT 2023 , Edited by admin on Sat Dec 16 02:16:42 GMT 2023
PRIMARY