U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Approval Year

Substance Class Nucleic Acid
Created
by admin
on Sat Dec 16 20:12:22 GMT 2023
Edited
by admin
on Sat Dec 16 20:12:22 GMT 2023
Nucleic Acid Type VECTOR
Nucleic Acid Subtype TRANSGENE
Sequence Type COMPLETE
Record UNII
A65Z4B94MY
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
Firicabtagene autoleucel transgene insert
Common Name English
Code System Code Type Description
FDA UNII
A65Z4B94MY
Created by admin on Sat Dec 16 20:12:22 GMT 2023 , Edited by admin on Sat Dec 16 20:12:22 GMT 2023
PRIMARY
Sugar Site Range Site Count
Deoxyribose (DNA) 1_1-1_4761 4761 / 4761
Linkage Site Range Site Count
Phosphate 1_2-1_4761 4760 / 4760
Name Property Type Amount Referenced Substance Defining Parameters References
(SIN)-LTR (ΔU3) NUCLEIC ACID FEATURE
Full elongation factor 1 alpha promoter (pEF1α) NUCLEIC ACID FEATURE
Core packaging signal (PSI) NUCLEIC ACID FEATURE
HIV-1 modified gag (Mod Gag) NUCLEIC ACID FEATURE
Partial Nef NUCLEIC ACID FEATURE
Rev response element (RRE) NUCLEIC ACID FEATURE
HIV-1 RU5 region NUCLEIC ACID FEATURE
Polypurine tract (PPT) NUCLEIC ACID FEATURE
Primer binding site (PBS) NUCLEIC ACID FEATURE
CD22 CAR NUCLEIC ACID FEATURE
Central polypurine tract (cPPT) NUCLEIC ACID FEATURE
Self-inactivating (SIN) LTR lacking the U3 region (ΔU3) NUCLEIC ACID FEATURE
HIV-1 RU5 region NUCLEIC ACID FEATURE