VID-400

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C24H20ClN3O
Molecular Weight	401.888
Optical Activity	UNSPECIFIED
Defined Stereocenters	1 / 1
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

ClC1=CC=C(C=C1)C2=CC=C(C=C2)C(=O)NC[C@H](N3C=CN=C3)C4=CC=CC=C4

InChI

InChIKey=FHHNSSGZEIVGMS-QHCPKHFHSA-N

InChI=1S/C24H20ClN3O/c25-22-12-10-19(11-13-22)18-6-8-21(9-7-18)24(29)27-16-23(28-15-14-26-17-28)20-4-2-1-3-5-20/h1-15,17,23H,16H2,(H,27,29)/t23-/m0/s1

HIDE SMILES / InChI

Molecular Formula	C24H20ClN3O
Molecular Weight	401.888
Charge	0
Count

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	1 / 1
E/Z Centers	0
Optical Activity	UNSPECIFIED

Approval Year

Targets

Primary Target	Pharmacology	Condition	Potency
Cytochrome P450 24A1 6 Target ID: CHEMBL4521 Sources: https://www.ncbi.nlm.nih.gov/pubmed/17240137	Inhibitor 8504

PubMed

Title	Date	PubMed
Homology model of 1alpha,25-dihydroxyvitamin D3 24-hydroxylase cytochrome P450 24A1 (CYP24A1): active site architecture and ligand binding.	2007-04	17240137
The mechanism of 1,25-dihydroxyvitamin D(3) autoregulation in keratinocytes.	2002-10-04	11956203
Selective inhibitors of CYP24: mechanistic tools to explore vitamin D metabolism in human keratinocytes.	2001-02-17	11179754

Patents

Substance Class	Chemical Created by `admin` on `Mon Mar 31 18:10:08 GMT 2025` Edited by `admin` on `Mon Mar 31 18:10:08 GMT 2025`
Record UNII	A53Q3K00XS
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

VID-400

Common Name

English

(R)-SDZ-285428

Preferred Name

English

(1,1'-BIPHENYL)-4-CARBOXAMIDE, 4'-CHLORO-N-((2R)-2-(1H-IMIDAZOL-1-YL)-2-PHENYLETHYL)-

Systematic Name

English

Code System Code Type Description

CAS

174262-10-3

Created by admin on Mon Mar 31 18:10:08 GMT 2025 , Edited by admin on Mon Mar 31 18:10:08 GMT 2025

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FDA UNII

A53Q3K00XS

Created by admin on Mon Mar 31 18:10:08 GMT 2025 , Edited by admin on Mon Mar 31 18:10:08 GMT 2025

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PUBCHEM

10476195

Created by admin on Mon Mar 31 18:10:08 GMT 2025 , Edited by admin on Mon Mar 31 18:10:08 GMT 2025

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EPA CompTox

DTXSID40169802

Created by admin on Mon Mar 31 18:10:08 GMT 2025 , Edited by admin on Mon Mar 31 18:10:08 GMT 2025

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