Stereochemistry | ABSOLUTE |
Molecular Formula | C11H14O5 |
Molecular Weight | 226.2259 |
Optical Activity | UNSPECIFIED |
Defined Stereocenters | 3 / 3 |
E/Z Centers | 0 |
Charge | 0 |
SHOW SMILES / InChI
SMILES
[H][C@]12CC=C(CO)[C@@]1([H])[C@H](O)OC=C2C(=O)OC
InChI
InChIKey=AZKVWQKMDGGDSV-BCMRRPTOSA-N
InChI=1S/C11H14O5/c1-15-10(13)8-5-16-11(14)9-6(4-12)2-3-7(8)9/h2,5,7,9,11-12,14H,3-4H2,1H3/t7-,9-,11-/m1/s1
Molecular Formula | C11H14O5 |
Molecular Weight | 226.2259 |
Charge | 0 |
Count |
MOL RATIO
1 MOL RATIO (average) |
Stereochemistry | ABSOLUTE |
Additional Stereochemistry | No |
Defined Stereocenters | 3 / 3 |
E/Z Centers | 0 |
Optical Activity | UNSPECIFIED |
Genipin is an aglycone derived from an iridoid glycoside called Geniposide (structure on the bottom) present in fruit of Gardenia jasmindides Ellis. Genipin have been demonstrated to have diverse pharmacological activities including anti-inflammatory, antioxidative, neuroprotective, and neurotrophic effects. Genipin is an excellent natural cross-linker for protein, collagen, gelatin, and chitosan cross-linking and can be considered as a substitute for glutaraldehyde. Due to cross-linking properties genipin can be used in controlling drug delivery.
In addition genipin exerts choleretic action.
CNS Activity
Originator
Approval Year
PubMed
Patents
Sample Use Guides
Oral genipin, at dose 50 mg/kg, exerts anti-inflammatory activity in carrageenan-induced rat paw edema
Route of Administration:
Oral