1-Hydroxybenzotriazole

Details

Stereochemistry	ACHIRAL
Molecular Formula	C6H5N3O
Molecular Weight	135.1234
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

ON1N=NC2=C1C=CC=C2

InChI

InChIKey=ASOKPJOREAFHNY-UHFFFAOYSA-N

InChI=1S/C6H5N3O/c10-9-6-4-2-1-3-5(6)7-8-9/h1-4,10H

HIDE SMILES / InChI

Molecular Formula	C6H5N3O
Molecular Weight	135.1234
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Approval Year

PubMed

Title	Date	PubMed
The first total synthesis of the peptaibol hypomurocin A1 and its conformation analysis: an application of the 'azirine/oxazolone method'.	2005 Sep	17193196
Role of 1-hydroxybenzotriazole in oxidation by laccase from Trametes versicolor. Kinetic analysis of the laccase-1-hydroxybenzotriazole couple.	2006 Dec	17038050
Applicability of Coriolopsis rigida for biodegradation of polycyclic aromatic hydrocarbons.	2006 Jul	16786260
Potential applications of the oxidoreductive enzymes in the decolorization and detoxification of textile and other synthetic dyes from polluted water: a review.	2006 Oct-Dec	17095432
Synthesis of polymer-bound 4-acetoxy-3-phenylbenzaldehyde derivatives: applications in solid-phase organic synthesis.	2006 Sep 29	16995713
Purification and characterization of the laccase secreted by the white rot fungus Perenniporia tephropora and its role in the decolourization of synthetic dyes.	2007 Apr	17381747
Laccase-catalyzed conversion of natural and synthetic hormones from a municipal wastewater.	2007 Aug	17585984
A conventional new procedure for N-acylation of unprotected amino acids.	2007 Jan	17202715
Production, purification and partial characterisation of a novel laccase from the white-rot fungus Panus tigrinus CBS 577.79.	2007 Jan	17013550
Design and synthesis of a 3,4-dehydroproline amide discovery library.	2007 Jul-Aug	17567173
Removal of lipophilic extractives from paper pulp by laccase and lignin-derived phenols as natural mediators.	2007 Jun 1	17612200
Kinetics of amide formation through carbodiimide/N-hydroxybenzotriazole (HOBt) couplings.	2007 Nov 9	17929977
[Conversion of polychlorophenols by laccases with 1-hydroxybenzotriazole as a mediator].	2007 Nov-Dec	18173112
[Hybrid Mn-peroxidases from basidiomycetes: a review].	2007 Sep-Oct	18038680
Cationic porphyrin induced a telomeric DNA to g-quadruplex form in water.	2008	18350116
Degradation of polycyclic aromatic hydrocarbons by Rigidoporus lignosus and its laccase in the presence of redox mediators.	2008 Apr	18350382
Analysis of flurbiprofen, ketoprofen and etodolac enantiomers by pre-column derivatization RP-HPLC and application to drug-protein binding in human plasma.	2008 Apr 14	18329215
Oxidative degradation of model lipids representative for main paper pulp lipophilic extractives by the laccase-mediator system.	2008 Aug	18563406
Substituting N(epsilon)-thioacetyl-lysine for N(epsilon)-acetyl-lysine in peptide substrates as a general approach to inhibiting human NAD(+)-dependent protein deacetylases.	2008 Jan	19325715
Modulation of protein kinase CK2 activity by fragments of CFTR encompassing F508 may reflect functional links with cystic fibrosis pathogenesis.	2008 Jul 29	18597485
Hexokinase II detachment from mitochondria triggers apoptosis through the permeability transition pore independent of voltage-dependent anion channels.	2008 Mar 19	18350175
Diverging Rh(I)-catalyzed carbocylization strategy to prepare a library of unique cyclic ethers.	2008 Mar-Apr	18271514
Comparative study of the efficiency of synthetic and natural mediators in laccase-assisted bleaching of eucalyptus kraft pulp.	2008 Nov	18499450
Engineering and Applications of fungal laccases for organic synthesis.	2008 Nov 20	19019256
Redox-mediated decolorization of Direct Red 23 and Direct Blue 80 catalyzed by bioaffinity-based immobilized tomato (Lycopersicon esculentum) peroxidase.	2008 Oct	18702080
Stereochemical preference in the reactions of N-protected L-amino acid 1-hydroxybenzotriazole esters with racemic amino acid derivatives.	2009	19275744
Synthesis and antitumor activity of amino acid ester derivatives containing 5-fluorouracil.	2009 Aug 25	19783913
Effect of metal ions on reactive dye decolorization by laccase from Ganoderma lucidum.	2009 Aug 30	19356850
Electron-transfer properties of short-lived N-oxyl radicals. Kinetic study of the reactions of benzotriazole-N-oxyl radicals with ferrocenes. Comparison with the phthalimide-N-oxyl radical.	2009 Aug 7	19522470
Application of laccase-natural mediator systems to sisal pulp: an effective approach to biobleaching or functionalizing pulp fibres?	2009 Dec	19574042
Enhanced transformation of malachite green by laccase of Ganoderma lucidum in the presence of natural phenolic compounds.	2009 Feb	19130052
Steroids linked with amide bond-extended cholesterol.	2009 Jan	18950651
Distributed Drug Discovery, Part 2: global rehearsal of alkylating agents for the synthesis of resin-bound unnatural amino acids and virtual D(3) catalog construction.	2009 Jan-Feb	19105725
Removal of estrogenic activity of iso-butylparaben and n-butylparaben by laccase in the presence of 1-hydroxybenzotriazole.	2009 Jul	19109757
Fusion of a family 1 carbohydrate binding module of Aspergillus niger to the Pycnoporus cinnabarinus laccase for efficient softwood kraft pulp biobleaching.	2009 Jul 15	19414054
Human neutrophil elastase responsive delivery from poly(ethylene glycol) hydrogels.	2009 Jun 8	19408953
Using both xylanase and laccase enzymes for pulp bleaching.	2009 Mar	19038541
Decolorization of direct dyes by immobilized turnip peroxidase in batch and continuous processes.	2009 Mar	18423852
Reactions of monoaryl-substituted methylenecyclobutanes and methylenecyclopropanes with 1-hydroxybenzotriazole (HOBt), 1-hydroxy-7-azabenzotriazole (HOAt), and 1-hydroxysuccinimide (HOSu).	2009 Mar 20	19222218
Decolorization of textile effluent by bitter gourd peroxidase immobilized on concanavalin A layered calcium alginate-starch beads.	2009 May 30	18977074
Oxidation of anthracene by immobilized laccase from Trametes versicolor.	2009 Nov	19564104
Dissecting the essentiality of the bifunctional trypanothione synthetase-amidase in Trypanosoma brucei using chemical and genetic methods.	2009 Nov	19558432
Hyperfine-shifted (13)C and (15)N NMR signals from Clostridium pasteurianum rubredoxin: extensive assignments and quantum chemical verification.	2009 Oct 28	19799419
Application of calcium alginate-starch entrapped bitter gourd (Momordica charantia) peroxidase for the removal of colored compounds from a textile effluent in batch as well as in continuous reactor.	2009 Sep	19015823
COMU: a safer and more effective replacement for benzotriazole-based uronium coupling reagents.	2009 Sep 21	19621394
Oxyma: an efficient additive for peptide synthesis to replace the benzotriazole-based HOBt and HOAt with a lower risk of explosion.	2009 Sep 21	19575348
Synergistic antibacterial and anti-inflammatory activity of temporin A and modified temporin B in vivo.	2009 Sep 28	19784377
Application of response surface methodological approach to optimise Reactive Black 5 decolouration by crude laccase from Trametes pubescens.	2009 Sep 30	19409701
Influence of very low doses of mediators on fungal laccase activity - nonlinearity beyond imagination.	2009 Sep 4	19732425
Enhanced transformation of triclosan by laccase in the presence of redox mediators.	2010 Jan	19854464

Patents

Substance Class	Chemical Created by `admin` on `Sat Dec 16 02:08:29 GMT 2023` Edited by `admin` on `Sat Dec 16 02:08:29 GMT 2023`
Record UNII	A2T929DMG4
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

1-Hydroxybenzotriazole

Systematic Name

English

1H-Benzotriazol-1-ol

Systematic Name

English

1-Hydroxy-1H-benzotriazole

Systematic Name

English

Benzazimidol

Common Name

English

1-HYDROXY-1H-BENZOTRIAZOLE [MI]

Common Name

English

Code System Code Type Description

PUBCHEM

75771