BRODIFACOUM

Details

Stereochemistry	MIXED
Molecular Formula	C31H23BrO3
Molecular Weight	523.417
Optical Activity	UNSPECIFIED
Defined Stereocenters	0 / 2
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

OC1=C(C2CC(CC3=C2C=CC=C3)C4=CC=C(C=C4)C5=CC=C(Br)C=C5)C(=O)OC6=C1C=CC=C6

InChI

InChIKey=VEUZZDOCACZPRY-UHFFFAOYSA-N

InChI=1S/C31H23BrO3/c32-24-15-13-20(14-16-24)19-9-11-21(12-10-19)23-17-22-5-1-2-6-25(22)27(18-23)29-30(33)26-7-3-4-8-28(26)35-31(29)34/h1-16,23,27,33H,17-18H2

HIDE SMILES / InChI

Molecular Formula	C31H23BrO3
Molecular Weight	523.417
Charge	0
Count

Stereochemistry	MIXED
Additional Stereochemistry	No
Defined Stereocenters	0 / 2
E/Z Centers	0
Optical Activity	UNSPECIFIED

Approval Year

PubMed

Title	Date	PubMed
Brodifacoum toxicity.	2002 Apr	11989188
Poisoned patients as potential organ donors: postal survey of transplant centres and intensive care units.	2003 Apr	12720561
Bias in pediatric brodifacoum exposure data.	2003 Feb	12592119
Brodifacoum toxicosis in two neonatal puppies.	2003 Mar	12637764
Superwarfarin and glass ingestion with prolonged coagulopathy requiring high-dose vitamin K1 therapy.	2003 Sep	14524650
Renal subcapsular hematoma associated with brodifacoum toxicosis in a dog.	2004 Apr	15080210
[Determination of serum brodifacoum with high performance liquid chromatography].	2006 May	16737595
Ingestion of superwarfarin leading to coagulopathy: a case report and review of the literature.	2006 Nov 28	17415322
Multiresidue analysis of seven anticoagulant rodenticides by high-performance liquid chromatography/electrospray/mass spectrometry.	2007 Feb 7	17263443
High-performance liquid chromatography coupled with electrospray ionization tandem mass spectrometry for the determination of flocoumafen and brodifacoum in whole blood.	2007 Jan-Feb	17177169
Brodifacoum poisoning with toxicokinetic data.	2007 Jun-Aug	17503253
Synthesis and structure-activity relationships of novel warfarin derivatives.	2007 Mar 15	17275317
Acquired deficiency of vitamin K-dependent clotting factors due to brodifacoum ingestion.	2008 Apr	18478986
Impending compartment syndrome and hemothorax after brodifacoum ingestion.	2008 Dec	19005444
Multi-residue analysis of eight anticoagulant rodenticides in animal plasma and liver using liquid chromatography combined with heated electrospray ionization tandem mass spectrometry.	2008 Jun 15	18502701
Pharmacokinetics of eight anticoagulant rodenticides in mice after single oral administration.	2008 Oct	19000263
[Study of the interaction mechanism between brodifacoum and DNA by spectroscopy].	2009 Apr	19626890
Novel mutations in the VKORC1 gene of wild rats and mice--a response to 50 years of selection pressure by warfarin?	2009 Feb 6	19200363
Thymic cystic degeneration, pseudoepitheliomatous hyperplasia, and hemorrhage in a dog with brodifacoum toxicosis.	2009 May	19176509
[Spectroscopic study on interaction of rodenticide brodifacoum with bovine serum albumin].	2009 Nov	20101972
Coagulopathy associated with superwarfarin exposure.	2009 Oct	19998733
(1)H and (13)C NMR chemical shift assignments and conformational analysis for the two diastereomers of the vitamin K epoxide reductase inhibitor brodifacoum.	2009 Oct	19569076
[Spectrofluorimetric study of supramolecular inclusion between rodenticide brodifacoum and beta-cyclodextrin and application].	2010 Apr	20545163
Korean patients with superwarfarin intoxication and their outcome.	2010 Dec	21165290
Anticoagulant rodenticides in three owl species from Western Canada, 1988-2003.	2010 Feb	19826750
Analysis of multiple anticoagulant rodenticides in animal blood and liver tissue using principles of QuEChERS method.	2010 Jun	20529461
Successful eradication of the European rabbit (Oryctolagus cuniculus) and house mouse (Mus musculus) from the island of Selvagem Grande (Macaronesian archipelago), in the Eastern Atlantic.	2010 Mar	21392324
Validation of a new liquid chromatography- tandem mass spectrometry ion-trap technique for the simultaneous determination of thirteen anticoagulant rodenticides, drugs, or natural products.	2010 Mar	20223102
Superwarfarin intoxication of unknown etiology accompanying hemoperitoneum in a patient on fluconazole therapy.	2010 Summer	20689146

Patents

Substance Class	Chemical Created by `admin` on `Fri Dec 15 18:32:40 GMT 2023` Edited by `admin` on `Fri Dec 15 18:32:40 GMT 2023`
Record UNII	A25P3CP5S7
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

BRODIFACOUM

Common Name

English

2H-1-BENZOPYRAN-2-ONE, 3-(3-(4'-BROMO(1,1'-BIPHENYL)-4-YL)-1,2,3,4-TETRAHYDRO-1-NAPHTHALENYL)-4-HYDROXY-

Systematic Name

English

3-(3-(4'-BROMOBIPHENYL-4-YL)-1,2,3,4-TETRAHYDRO-1-NAPHTHYL)-4-HYDROXYCOUMARIN

Systematic Name

English

PP-581

Code

English

BRODIMAT

Brand Name

English

BRODIFACOUM [ISO]

Common Name

English

KLERAT

Brand Name

English

VOLID

Brand Name

English

BRODIFACOUM [HSDB]

Common Name

English

BRODIFACOUM [MI]

Common Name

English

BROMFENACOUM

Common Name

English

BRODIFACOUM [NFLIS-DRUG]

Common Name

English

WBA-8119

Code

English

TALON

Brand Name

English

BRODIFACOUM [MART.]

Common Name

English

Classification Tree Code System Code

EPA PESTICIDE CODE

112701