BRODIFACOUM

Details

Stereochemistry	MIXED
Molecular Formula	C31H23BrO3
Molecular Weight	523.417
Optical Activity	UNSPECIFIED
Defined Stereocenters	0 / 2
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

OC1=C(C2CC(CC3=CC=CC=C23)C4=CC=C(C=C4)C5=CC=C(Br)C=C5)C(=O)OC6=C1C=CC=C6

InChI

InChIKey=VEUZZDOCACZPRY-UHFFFAOYSA-N

InChI=1S/C31H23BrO3/c32-24-15-13-20(14-16-24)19-9-11-21(12-10-19)23-17-22-5-1-2-6-25(22)27(18-23)29-30(33)26-7-3-4-8-28(26)35-31(29)34/h1-16,23,27,33H,17-18H2

HIDE SMILES / InChI

Molecular Formula	C31H23BrO3
Molecular Weight	523.417
Charge	0
Count

Stereochemistry	MIXED
Additional Stereochemistry	No
Defined Stereocenters	0 / 2
E/Z Centers	0
Optical Activity	UNSPECIFIED

Approval Year

PubMed

Title	Date	PubMed
Korean patients with superwarfarin intoxication and their outcome.	2010-12	21165290
Warfarin toxicity and individual variability-clinical case.	2010-11	22069565
Analysis of multiple anticoagulant rodenticides in animal blood and liver tissue using principles of QuEChERS method.	2010-06	20529461
[Spectrofluorimetric study of supramolecular inclusion between rodenticide brodifacoum and beta-cyclodextrin and application].	2010-04	20545163
Successful eradication of the European rabbit (Oryctolagus cuniculus) and house mouse (Mus musculus) from the island of Selvagem Grande (Macaronesian archipelago), in the Eastern Atlantic.	2010-03	21392324
Validation of a new liquid chromatography- tandem mass spectrometry ion-trap technique for the simultaneous determination of thirteen anticoagulant rodenticides, drugs, or natural products.	2010-03	20223102
Anticoagulant rodenticides in three owl species from Western Canada, 1988-2003.	2010-02	19826750
Superwarfarin intoxication of unknown etiology accompanying hemoperitoneum in a patient on fluconazole therapy.	2010	20689146
[Spectroscopic study on interaction of rodenticide brodifacoum with bovine serum albumin].	2009-11	20101972
Coagulopathy associated with superwarfarin exposure.	2009-10	19998733
(1)H and (13)C NMR chemical shift assignments and conformational analysis for the two diastereomers of the vitamin K epoxide reductase inhibitor brodifacoum.	2009-10	19569076
Thymic cystic degeneration, pseudoepitheliomatous hyperplasia, and hemorrhage in a dog with brodifacoum toxicosis.	2009-05	19176509
[Study of the interaction mechanism between brodifacoum and DNA by spectroscopy].	2009-04	19626890
Impact of pesticides use in agriculture: their benefits and hazards.	2009-03	21217838
Novel mutations in the VKORC1 gene of wild rats and mice--a response to 50 years of selection pressure by warfarin?	2009-02-06	19200363
Impending compartment syndrome and hemothorax after brodifacoum ingestion.	2008-12	19005444
Pharmacokinetics of eight anticoagulant rodenticides in mice after single oral administration.	2008-10	19000263
Multi-residue analysis of eight anticoagulant rodenticides in animal plasma and liver using liquid chromatography combined with heated electrospray ionization tandem mass spectrometry.	2008-06-15	18502701
Raptor toxicology.	2008-05	18406387
Acquired deficiency of vitamin K-dependent clotting factors due to brodifacoum ingestion.	2008-04	18478986
Second generation anticoagulant rodenticides in tawny owls (Strix aluco) from Great Britain.	2008-03-15	18082246
Invasive rodent eradication on islands.	2007-10	17883491
Exposure of raptors and waterbirds to anticoagulant rodenticides (difenacoum, bromadiolone, coumatetralyl, coumafen, brodifacoum): epidemiological survey in Loire Atlantique (France).	2007-07	17487436
Piroxicam-induced hepatic and renal histopathological changes in mice.	2007-06-01	21503258
Fatal brodifacoum poisoning in a pony.	2007-06	17616062
Brodifacoum poisoning with toxicokinetic data.	2007-05-16	17503253
Synthesis and structure-activity relationships of novel warfarin derivatives.	2007-03-15	17275317
[Determination of five 4-hydroxycoumarin rodenticides in whole blood by high performance liquid chromatography with fluorescence detection].	2007-03	17580689
Multiresidue analysis of seven anticoagulant rodenticides by high-performance liquid chromatography/electrospray/mass spectrometry.	2007-02-07	17263443
Threats and control of the brown necked ravens (Corvus ruficollis) in Egypt.	2007	18399444
High-performance liquid chromatography coupled with electrospray ionization tandem mass spectrometry for the determination of flocoumafen and brodifacoum in whole blood.	2006-12-21	17177169
Ingestion of superwarfarin leading to coagulopathy: a case report and review of the literature.	2006-11-28	17415322
[Determination of serum brodifacoum with high performance liquid chromatography].	2006-05	16737595
A 44-year-old woman with hematemesis and cutaneous hemorrhages as a result of superwarfarin poisoning.	2006-05	16717370
Rapid identification of surreptitious brodifacoum poisoning by analysis of vitamin K-dependent factor activity.	2006-05	16635728
Rapid determination of three anticoagulant rodenticides in whole blood by liquid chromatography coupled with electrospray ionization mass spectrometry.	2006	16921552
Accidental discharge of brodifacoum baits in a tidal marine environment: a case study.	2005-05	16097326
Renal subcapsular hematoma associated with brodifacoum toxicosis in a dog.	2004-04	15080210
Superwarfarin and glass ingestion with prolonged coagulopathy requiring high-dose vitamin K1 therapy.	2003-09	14524650
Poisoned patients as potential organ donors: postal survey of transplant centres and intensive care units.	2003-04	12720561
Brodifacoum toxicosis in two neonatal puppies.	2003-03	12637764
Bias in pediatric brodifacoum exposure data.	2003-02	12592119
Spatial and temporal analysis of second-generation anticoagulant rodenticide residues in polecats (Mustela putorius) from throughout their range in Britain, 1992-1999.	2003	12531306
Acute, unintentional pediatric brodifacoum ingestions.	2002-06	12066002
Brodifacoum toxicity.	2002-04	11989188
Shortfalls using second-generation anticoagulant rodenticides.	2002-03	12216801
Assessment of risks of brodifacoum to non-target birds and mammals in New Zealand.	2002-02	11898799

Patents

Substance Class	Chemical Created by `admin` on `Mon Mar 31 19:15:02 GMT 2025` Edited by `admin` on `Mon Mar 31 19:15:02 GMT 2025`
Record UNII	A25P3CP5S7
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

BRODIMAT

Preferred Name

English

BRODIFACOUM

Common Name

English

2H-1-BENZOPYRAN-2-ONE, 3-(3-(4'-BROMO(1,1'-BIPHENYL)-4-YL)-1,2,3,4-TETRAHYDRO-1-NAPHTHALENYL)-4-HYDROXY-

Systematic Name

English

3-(3-(4'-BROMOBIPHENYL-4-YL)-1,2,3,4-TETRAHYDRO-1-NAPHTHYL)-4-HYDROXYCOUMARIN

Systematic Name

English

PP-581

Code

English

BRODIFACOUM [ISO]

Common Name

English

KLERAT

Brand Name

English

VOLID

Brand Name

English

BRODIFACOUM [HSDB]

Common Name

English

BRODIFACOUM [MI]

Common Name

English

BROMFENACOUM

Common Name

English

BRODIFACOUM [NFLIS-DRUG]

Common Name

English

WBA-8119

Code

English

TALON

Brand Name

English

BRODIFACOUM [MART.]

Common Name

English

Classification Tree Code System Code

EPA PESTICIDE CODE

112701