ABRINEURIN

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Approval Year

Substance Class	Protein Created by `admin` on `Mon Mar 31 22:48:24 GMT 2025` Edited by `admin` on `Mon Mar 31 22:48:24 GMT 2025`
Protein Type	GROWTH FACTOR
Protein Sub Type
Sequence Origin	HUMAN
Sequence Type	COMPLETE
Record UNII	A1ED6W905I
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

abrineurin [INN]

Preferred Name

English

ABRINEURIN

Official Name

English

BRAIN-DERIVED NEUROTROPHIC FACTOR HUMAN

Common Name

English

BRAIN-DERIVED NEUROTROPHIC FACTOR, HUMAN

Common Name

English

BDNF HUMAN

Common Name

English

ABRINEURIN [USAN]

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C78272

Created by admin on Mon Mar 31 22:48:24 GMT 2025 , Edited by admin on Mon Mar 31 22:48:24 GMT 2025

Code System Code Type Description

FDA UNII

A1ED6W905I

Created by admin on Mon Mar 31 22:48:24 GMT 2025 , Edited by admin on Mon Mar 31 22:48:24 GMT 2025

PRIMARY

NCI_THESAURUS

C154295

Created by admin on Mon Mar 31 22:48:24 GMT 2025 , Edited by admin on Mon Mar 31 22:48:24 GMT 2025

PRIMARY

CAS

178535-93-8

Created by admin on Mon Mar 31 22:48:24 GMT 2025 , Edited by admin on Mon Mar 31 22:48:24 GMT 2025

PRIMARY

SMS_ID

100000183305

Created by admin on Mon Mar 31 22:48:24 GMT 2025 , Edited by admin on Mon Mar 31 22:48:24 GMT 2025

PRIMARY

UNIPROT

P23560

Created by admin on Mon Mar 31 22:48:24 GMT 2025 , Edited by admin on Mon Mar 31 22:48:24 GMT 2025

PRIMARY

USAN

II-78

Created by admin on Mon Mar 31 22:48:24 GMT 2025 , Edited by admin on Mon Mar 31 22:48:24 GMT 2025

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ChEMBL

CHEMBL2108230

Created by admin on Mon Mar 31 22:48:24 GMT 2025 , Edited by admin on Mon Mar 31 22:48:24 GMT 2025

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INN

7933

Created by admin on Mon Mar 31 22:48:24 GMT 2025 , Edited by admin on Mon Mar 31 22:48:24 GMT 2025

PRIMARY

From	To
1_13	1_80

Related Record Type Details


					AR899YG72E

ACTIVATOR OF EXPRESSION->TARGET

Comments:

The endogenous mRNA level of BDNF in 1321N1 astrocytes seemed to be much higher than that of NGF, slightly increased BDNF expression by about 1.5 fold

Qualification:

MAXIMUM FOLD INCREASE

Amount:


					YVE9U408ZL

NSI-189

ACTIVATOR OF EXPRESSION->TARGET

Amount:


					VV8CZC8PAS

P-21

ACTIVATOR -> TARGET

Comments:

DOES NOT BIND TO RECEPTOR OR BDNF BUT BLOCKS INHIBITORS OF BDNF

Amount:


					G8F9Q5LZD4

ACTIVATOR OF EXPRESSION->TARGET

Comments:

The endogenous mRNA level of BDNF in 1321N1 astrocytes seemed to be much higher than that of NGF, slightly increased BDNF expression by about 1.5 fold

Qualification:

MAXIMUM FOLD INCREASE

Amount:

Related Record Type Details


					A1ED6W905I

ACTIVE MOIETY

Amount:

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
Molecular Formula	CHEMICAL
MOL_WEIGHT	CHEMICAL