U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Approval Year

Substance Class Protein
Created
by admin
on Sat Dec 16 09:42:29 GMT 2023
Edited
by admin
on Sat Dec 16 09:42:29 GMT 2023
Protein Type GROWTH FACTOR
Protein Sub Type
Sequence Origin HUMAN
Sequence Type COMPLETE
Record UNII
A1ED6W905I
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
ABRINEURIN
INN   USAN  
USAN   INN  
Official Name English
BRAIN-DERIVED NEUROTROPHIC FACTOR HUMAN
Common Name English
abrineurin [INN]
Common Name English
BRAIN-DERIVED NEUROTROPHIC FACTOR, HUMAN
Common Name English
BDNF HUMAN
Common Name English
ABRINEURIN [USAN]
Common Name English
Classification Tree Code System Code
NCI_THESAURUS C78272
Created by admin on Sat Dec 16 09:42:29 GMT 2023 , Edited by admin on Sat Dec 16 09:42:29 GMT 2023
Code System Code Type Description
FDA UNII
A1ED6W905I
Created by admin on Sat Dec 16 09:42:29 GMT 2023 , Edited by admin on Sat Dec 16 09:42:29 GMT 2023
PRIMARY
NCI_THESAURUS
C154295
Created by admin on Sat Dec 16 09:42:29 GMT 2023 , Edited by admin on Sat Dec 16 09:42:29 GMT 2023
PRIMARY
CAS
178535-93-8
Created by admin on Sat Dec 16 09:42:29 GMT 2023 , Edited by admin on Sat Dec 16 09:42:29 GMT 2023
PRIMARY
UNIPROT
P23560
Created by admin on Sat Dec 16 09:42:29 GMT 2023 , Edited by admin on Sat Dec 16 09:42:29 GMT 2023
PRIMARY
USAN
II-78
Created by admin on Sat Dec 16 09:42:29 GMT 2023 , Edited by admin on Sat Dec 16 09:42:29 GMT 2023
PRIMARY
ChEMBL
CHEMBL2108230
Created by admin on Sat Dec 16 09:42:29 GMT 2023 , Edited by admin on Sat Dec 16 09:42:29 GMT 2023
PRIMARY
INN
7933
Created by admin on Sat Dec 16 09:42:29 GMT 2023 , Edited by admin on Sat Dec 16 09:42:29 GMT 2023
PRIMARY
From To
1_13 1_80
Related Record Type Details
ACTIVATOR OF EXPRESSION->TARGET
The endogenous mRNA level of BDNF in 1321N1 astrocytes seemed to be much higher than that of NGF, slightly increased BDNF expression by about 1.5 fold
MAXIMUM FOLD INCREASE
ACTIVATOR OF EXPRESSION->TARGET
ACTIVATOR -> TARGET
DOES NOT BIND TO RECEPTOR OR BDNF BUT BLOCKS INHIBITORS OF BDNF
ACTIVATOR OF EXPRESSION->TARGET
The endogenous mRNA level of BDNF in 1321N1 astrocytes seemed to be much higher than that of NGF, slightly increased BDNF expression by about 1.5 fold
MAXIMUM FOLD INCREASE
Related Record Type Details
ACTIVE MOIETY
Name Property Type Amount Referenced Substance Defining Parameters References
Molecular Formula CHEMICAL
MOL_WEIGHT CHEMICAL