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Details

Stereochemistry ABSOLUTE
Molecular Formula C4H11NO2
Molecular Weight 105.1356
Optical Activity UNSPECIFIED
Defined Stereocenters 2 / 2
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of L-THREONINOL

SMILES

C[C@@H](O)[C@H](N)CO

InChI

InChIKey=MUVQIIBPDFTEKM-QWWZWVQMSA-N
InChI=1S/C4H11NO2/c1-3(7)4(5)2-6/h3-4,6-7H,2,5H2,1H3/t3-,4-/m1/s1

HIDE SMILES / InChI

Molecular Formula C4H11NO2
Molecular Weight 105.1356
Charge 0
Count
Stereochemistry ABSOLUTE
Additional Stereochemistry No
Defined Stereocenters 2 / 2
E/Z Centers 0
Optical Activity UNSPECIFIED

Approval Year

PubMed

PubMed

TitleDatePubMed
Synthesis and structural properties of oligonucleotides covalently linked to acridine and quindoline derivatives through a threoninol linker.
2010-11-01
Unexpectedly stable artificial duplex from flexible acyclic threoninol.
2010-10-27
Positively charged base surrogate for highly stable "base pairing" through electrostatic and stacking interactions.
2009-07-29
Dye labelling of nucleosides.
2009-04
Modulation of pK(a) of Brooker's merocyanine by DNA hybridization.
2009-02
In-stem molecular beacon containing a pseudo base pair of threoninol nucleotides for the removal of background emission.
2009
Spectroscopic labeling of A, S/T in the 1H-15N HSQC spectrum of uniformly (15N-13C) labeled proteins.
2008-10
Threoninol as a scaffold of dyes (threoninol-nucleotide) and their stable interstrand clustering in duplexes.
2008-08-21
Molecular design for reversing the photoswitching mode of turning ON and OFF DNA hybridization.
2008-03-07
Incorporation of cationic dyes into DNA for distinct stabilization of duplex.
2008
Preparation of coherent hetero clusters with threoninol scaffold.
2008
Synthesis and evaluation of glycosylated octreotate analogues labeled with radioiodine and 211At via a tin precursor.
2006-01-19
Covalent incorporation of methyl red dyes into double-stranded DNA for their ordered clustering.
2006-01-11
Design of phosphoramidite monomer for optimal incorporation of functional intercalator to main chain of oligonucleotide.
2005-03-17
Solid-phase synthesis and screening of macrocyclic nucleotide-hybrid compounds targeted to hepatitis C NS5B.
2004-01-05
Induced fit and kinetic mechanism of adenylation catalyzed by Escherichia coli threonyl-tRNA synthetase.
2003-12-30
Patents
Substance Class Chemical
Created
by admin
on Mon Mar 31 20:58:36 GMT 2025
Edited
by admin
on Mon Mar 31 20:58:36 GMT 2025
Record UNII
A16V466XOD
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
L-THREONINOL
Systematic Name English
THREONINOL,L-
Preferred Name English
1,3-BUTANEDIOL, 2-AMINO-, (2R,3R)-
Systematic Name English
Code System Code Type Description
EPA CompTox
DTXSID30186028
Created by admin on Mon Mar 31 20:58:36 GMT 2025 , Edited by admin on Mon Mar 31 20:58:36 GMT 2025
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FDA UNII
A16V466XOD
Created by admin on Mon Mar 31 20:58:36 GMT 2025 , Edited by admin on Mon Mar 31 20:58:36 GMT 2025
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DRUG BANK
DB01724
Created by admin on Mon Mar 31 20:58:36 GMT 2025 , Edited by admin on Mon Mar 31 20:58:36 GMT 2025
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CAS
3228-51-1
Created by admin on Mon Mar 31 20:58:36 GMT 2025 , Edited by admin on Mon Mar 31 20:58:36 GMT 2025
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PUBCHEM
2033049
Created by admin on Mon Mar 31 20:58:36 GMT 2025 , Edited by admin on Mon Mar 31 20:58:36 GMT 2025
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