Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C12H11N3.C2H4O2 |
| Molecular Weight | 257.2878 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
CC(O)=O.CC1=C(N)N=C2NC3=C(C=CC=C3)C2=C1
InChI
InChIKey=DKHDTSYVAJMKFM-UHFFFAOYSA-N
InChI=1S/C12H11N3.C2H4O2/c1-7-6-9-8-4-2-3-5-10(8)14-12(9)15-11(7)13;1-2(3)4/h2-6H,1H3,(H3,13,14,15);1H3,(H,3,4)
| Molecular Formula | C2H4O2 |
| Molecular Weight | 60.052 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
| Molecular Formula | C12H11N3 |
| Molecular Weight | 197.2358 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Initiating activity in a two-stage mouse skin model of nine mutagenic pyrolysates of amino acids, soybean globulin and proteinaceous food. | 1987 Sep |
|
| Inhibition of human brain aromatic L-amino acid decarboxylase by cooked food-derived 3-amino-1-methyl-5H-pyrido[4,3-b]indole (Trp-P-2) and other heterocyclic amines. | 1990 Aug 24 |
|
| The food mutagen 2-amino-9H-pyrido[2,3-b]indole (AalphaC) but not its methylated form (MeAalphaC) increases intestinal tumorigenesis in neonatally exposed multiple intestinal neoplasia mice. | 2002 Aug |
|
| Impact of five cytochrome p450 enzymes on the metabolism of two heterocyclic aromatic amines, 2-amino-9H-pyrido[2,3-b]indole (AalphaC) and 2-amino-3-methyl-9H-pyrido[2,3-b]indole (MeAalphaC). | 2003 May |
|
| Syntheses of DNA adducts of two heterocyclic amines, 2-amino-3-methyl-9H-pyrido[2,3-b]indole (MeAalphaC) and 2-amino-9H-pyrido[2,3-b]indole (AalphaC) and identification of DNA adducts in organs from rats dosed with MeAalphaC. | 2004 Aug |
|
| Modulation of cytochrome P450 1A1 by food-derived heterocyclic aromatic amines. | 2004 Jul 1 |
|
| Identification of metabolites in urine and feces from rats dosed with the heterocyclic amine, 2-amino-3-methyl-9H-pyrido[2,3-b]indole (MeA alpha C). | 2004 Jun |
|
| Bioactivation of the heterocyclic aromatic amine 2-amino-3-methyl-9H-pyrido [2,3-b]indole (MeAalphaC) in recombinant test systems expressing human xenobiotic-metabolizing enzymes. | 2004 May |
|
| Quantitation of carcinogenic heterocyclic aromatic amines and detection of novel heterocyclic aromatic amines in cooked meats and grill scrapings by HPLC/ESI-MS. | 2005 Apr 20 |
Patents
| Substance Class |
Chemical
Created
by
admin
on
Edited
Sat Dec 16 08:00:41 GMT 2023
by
admin
on
Sat Dec 16 08:00:41 GMT 2023
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| Record UNII |
A0Y80T1Y4C
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| Record Status |
Validated (UNII)
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| Record Version |
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117831-29-5
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DTXSID4020799
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147227
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A0Y80T1Y4C
Created by
admin on Sat Dec 16 08:00:41 GMT 2023 , Edited by admin on Sat Dec 16 08:00:41 GMT 2023
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PRIMARY |