GEMCITABINE TRIPHOSPHATE

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C9H14F2N3O13P3
Molecular Weight	503.1379
Optical Activity	UNSPECIFIED
Defined Stereocenters	3 / 3
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

NC1=NC(=O)N(C=C1)[C@@H]2O[C@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)[C@@H](O)C2(F)F

InChI

InChIKey=YMOXEIOKAJSRQX-QPPQHZFASA-N

InChI=1S/C9H14F2N3O13P3/c10-9(11)6(15)4(25-7(9)14-2-1-5(12)13-8(14)16)3-24-29(20,21)27-30(22,23)26-28(17,18)19/h1-2,4,6-7,15H,3H2,(H,20,21)(H,22,23)(H2,12,13,16)(H2,17,18,19)/t4-,6-,7-/m1/s1

HIDE SMILES / InChI

Molecular Formula	C9H14F2N3O13P3
Molecular Weight	503.1379
Charge	0
Count

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	3 / 3
E/Z Centers	0
Optical Activity	UNSPECIFIED

Approval Year

PubMed

Title	Date	PubMed
Assessment of the effect of phosphorylated metabolites of anti-human immunodeficiency virus and anti-hepatitis B virus pyrimidine analogs on the behavior of human deoxycytidylate deaminase.	2003 Jan	12488542
Pharmacokinetic evaluation of gemcitabine and 2',2'-difluorodeoxycytidine-5'-triphosphate after prolonged infusion in patients affected by different solid tumors.	2006 May	16807444
Prolonged versus standard gemcitabine infusion: translation of molecular pharmacology to new treatment strategy.	2008 Mar	18378536
In vitro study on the schedule-dependency of the interaction between pemetrexed, gemcitabine and irradiation in non-small cell lung cancer and head and neck cancer cells.	2010 Aug 19	20723210

Patents

Substance Class	Chemical Created by `admin` on `Sat Dec 16 09:33:17 UTC 2023` Edited by `admin` on `Sat Dec 16 09:33:17 UTC 2023`
Record UNII	A0Q7SO4OZE
Record Status	`Validated (UNII)`
Record Version