Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C4H9F3Si |
| Molecular Weight | 142.195 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
C[Si](C)(C)C(F)(F)F
InChI
InChIKey=MWKJTNBSKNUMFN-UHFFFAOYSA-N
InChI=1S/C4H9F3Si/c1-8(2,3)4(5,6)7/h1-3H3
| Molecular Formula | C4H9F3Si |
| Molecular Weight | 142.195 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Cinchona alkaloid-catalyzed asymmetric trifluoromethylation of alkynyl ketones with trimethylsilyl trifluoromethane. | 2010-11-19 |
|
| Copper-mediated oxidative trifluoromethylation of boronic acids. | 2010-11-05 |
|
| Benzoyl peroxide (BPO)-promoted oxidative trifluoromethylation of tertiary amines with trimethyl(trifluoromethyl)silane. | 2010-09-14 |
|
| Catalytic enantioselective trifluoromethylation of azomethine imines with trimethyl(trifluoromethyl)silane. | 2009 |
|
| Enantiopure quaternary alpha-trifluoromethyl-alpha-alkoxyaldehydes from L-tartaric acid derived ketoamides. | 2008-10-17 |
|
| Copper-catalyzed silylation of cyclopropenes using (trifluoromethyl)trimethylsilane. | 2008-03-07 |
|
| Addition of trifluoromethyltrimethylsilane to acyl phosphonates: synthesis of TMS-protected 1-alkyl-1-trifluoromethyl-1-hydroxyphosphonates and 1-aryldifluoroethenyl phosphates. | 2007-10-26 |
|
| Synthesis of enantiopure trifluoromethyl building blocks via a highly chemo- and diastereoselective nucleophilic trifluoromethylation of tartaric acid-derived diketones. | 2007-02-16 |
|
| Facile synthesis of TMS-protected trifluoromethylated alcohols using trifluoromethyltrimethylsilane (TMSCF3) and various nucleophilic catalysts in DMF. | 2006-09-01 |
|
| Preparation of tri- and difluoromethylated amines from aldimines using (trifluoromethyl)trimethylsilane. | 2006-08-03 |
|
| An efficient synthesis of enantiomerically enriched trifluoromethylated 1,2-diols and 1,2-amino alcohols with quaternary stereocenters by diastereoselective addition of TMSCF3 to chiral 2-acyl-1,3-perhydrobenzoxazines. | 2006-03-03 |
|
| How trimethyl(trifluoromethyl)silane reacts with itself in the presence of naked fluoride--a one-pot synthesis of bis([15]crown-5)cesium 1,1,1,3,5,5,5-heptafluoro-2,4-bis(trifluoromethyl)pentenide. | 2005-11-04 |
|
| Gas phase structure of Ruppert's reagent, CF3SiMe3. | 2005-09-22 |
|
| Trifluoromethyl derivatives of pentacyclo[5.4.0.0(2,6).0(3,10).0(5,9)]undecane. | 2005-04 |
|
| The first Cu(I)-mediated nucleophilic trifluoromethylation reactions using (trifluoromethyl)trimethylsilane in ionic liquids. | 2004-10-07 |
|
| Early transition-metal perfluoroalkyl complexes. | 2003-12-03 |
|
| Regioselective nucleophilic 1,4-trifluoromethylation of 2-polyfluoroalkylchromones with (trifluoromethyl)trimethylsilane. Synthesis of fluorinated analogs of natural 2,2-dimethylchroman-4-ones and 2,2-dimethylchromenes. | 2003-10-03 |
|
| Preparation of tri- and difluoromethylsilanes via an unusual magnesium metal-mediated reductive tri- and difluoromethylation of chlorosilanes using tri- and difluoromethyl sulfides, sulfoxides, and sulfones. | 2003-05-30 |
|
| Stereoselective synthesis of trifluoromethylated vicinal ethylenediamines with alpha-amino N-tert-butanesulfinimines and TMSCF3. | 2002-06-12 |
|
| Abstracts of the XV International Ecdysone Workshop. June 30- July 6, 2002. Kolymbari Crete, Greece. | 2002 |
|
| Bis(acylsilanes) and trifluoromethyltrimethylsilane: a useful system for the synthesis of cyclic 2,2-difluoro-3-trialkylsilyl-1,3-ketols and cyclic 2-fluoro-1,3-diketones(1). | 2001-06-29 |
|
| Acetyltrimethylsilane, trifluoromethyltrimethylsilane, and prenyl esters: a three-component system for the synthesis of gem-difluoroanalogues of monoterpenes. | 2001-06-15 |
|
| Mixed organofluorine-organosilicon chemistry. 13. One-pot synthesis of difluoroaldols from acylsilanes and trifluoromethyltrimethylsilane. application to the synthesis of a difluoro analogue of egomaketone. | 2001-03-23 |
|
| Diketo compounds with (trifluoromethyl)trimethylsilane: double nucleophilic trifluoromethylation reactions. | 2001-02-23 |
|
| A simple and efficient approach for the synthesis of fluorinated and nonfluorinated octaethylporphyrin-based benzochlorins with variable lipophilicity, their in vivo tumor uptake, and the preliminary in vitro photosensitizing efficacy. | 2001-02-23 |
|
| Reactions of difluoroenoxysilanes with glycosyl donors: synthesis of difluoro-C-glycosides and difluoro-C-disaccharides. | 2001 |
| Substance Class |
Chemical
Created
by
admin
on
Edited
Mon Mar 31 22:33:18 GMT 2025
by
admin
on
Mon Mar 31 22:33:18 GMT 2025
|
| Record UNII |
A009786QPJ
|
| Record Status |
Validated (UNII)
|
| Record Version |
|
-
Download
| Name | Type | Language | ||
|---|---|---|---|---|
|
Preferred Name | English | ||
|
Systematic Name | English | ||
|
Systematic Name | English | ||
|
Systematic Name | English | ||
|
Systematic Name | English | ||
|
Common Name | English | ||
|
Systematic Name | English |
| Code System | Code | Type | Description | ||
|---|---|---|---|---|---|
|
DTXSID20338998
Created by
admin on Mon Mar 31 22:33:18 GMT 2025 , Edited by admin on Mon Mar 31 22:33:18 GMT 2025
|
PRIMARY | |||
|
81290-20-2
Created by
admin on Mon Mar 31 22:33:18 GMT 2025 , Edited by admin on Mon Mar 31 22:33:18 GMT 2025
|
PRIMARY | |||
|
Trifluoromethyltrimethylsilane
Created by
admin on Mon Mar 31 22:33:18 GMT 2025 , Edited by admin on Mon Mar 31 22:33:18 GMT 2025
|
PRIMARY | |||
|
A009786QPJ
Created by
admin on Mon Mar 31 22:33:18 GMT 2025 , Edited by admin on Mon Mar 31 22:33:18 GMT 2025
|
PRIMARY | |||
|
m11121
Created by
admin on Mon Mar 31 22:33:18 GMT 2025 , Edited by admin on Mon Mar 31 22:33:18 GMT 2025
|
PRIMARY | Merck Index | ||
|
552549
Created by
admin on Mon Mar 31 22:33:18 GMT 2025 , Edited by admin on Mon Mar 31 22:33:18 GMT 2025
|
PRIMARY |