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Details

Stereochemistry ACHIRAL
Molecular Formula C20H21NO3
Molecular Weight 323.3856
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of DIMEFLINE

SMILES

COC1=CC=C2C(=O)C(C)=C(OC2=C1CN(C)C)C3=CC=CC=C3

InChI

InChIKey=ZXFQRFXLFWWKLX-UHFFFAOYSA-N
InChI=1S/C20H21NO3/c1-13-18(22)15-10-11-17(23-4)16(12-21(2)3)20(15)24-19(13)14-8-6-5-7-9-14/h5-11H,12H2,1-4H3

HIDE SMILES / InChI
Molecular Formula C20H21NO3
Molecular Weight 323.3856
Charge 0
Count
MOL RATIO 1 MOL RATIO (average)
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Description

DIMEFLINE is a pneumokinetic and respiratory stimulant. It has been used for the treatment of respiratory insufficiency. The mechanism of action is unknown.

CNS Activity

CNS Active
4,002

Originator

Da Re, P. et al.
2

Approval Year

Unknown
149,124

Conditions

ConditionModalityTargetsHighest PhaseProduct
Asthma
244
 Primary
Not Provided
511
DIMEFLINE
Respiratory insufficiency
6
 Primary
Not Provided
511
DIMEFLINE
Pulmonary emphysema
6
 Primary
Not Provided
511
DIMEFLINE

PubMed

Patents

CN101182318B
2

Sample Use Guides

In Vivo Use Guide
Unknown
Route of Administration: Other
In Vitro Use Guide
Unknown
Substance Class Chemical
Record UNII
9WII5M0DU3
Record Status Validated (UNII)
Record Version
NIH
NCATS
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