rafutrombopag

Investigational

Details

Stereochemistry	ACHIRAL
Molecular Formula	C25H22N4O5
Molecular Weight	458.466
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	1
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CC1=NN(C(=O)\C1=N/NC2=C(O)C(=CC=C2)C3=CC=C(O3)C(O)=O)C4=CC=C5CCCCC5=C4

InChI

InChIKey=BDGGFTDRPHKXFC-QYQHSDTDSA-N

InChI=1S/C25H22N4O5/c1-14-22(24(31)29(28-14)17-10-9-15-5-2-3-6-16(15)13-17)27-26-19-8-4-7-18(23(19)30)20-11-12-21(34-20)25(32)33/h4,7-13,26,30H,2-3,5-6H2,1H3,(H,32,33)/b27-22-

HIDE SMILES / InChI

Molecular Formula	C25H22N4O5
Molecular Weight	458.466
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	1
Optical Activity	NONE

Approval Year

Substance Class	Chemical Created by `admin` on `Mon Mar 31 23:16:03 GMT 2025` Edited by `admin` on `Mon Mar 31 23:16:03 GMT 2025`
Record UNII	9WGT51BDDL
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

SHR-8735

Preferred Name

English

rafutrombopag

Official Name

English

(Z)-5-(2-HYDROXY-3-(2-(3-METHYL-5-OXO-1-(5,6,7,8-TETRAHYDRONAPHTHALEN-2-YL)-1H-PYRAZOL-4(5H)-YLIDENE)HYDRAZINYL)PHENYL) FURAN-2-CARBOXYLIC ACID

Systematic Name

English

rafutrombopag [INN]

Common Name

English

Hetrombopag [WHO-DD]

Common Name

English

HETROMBOPAG

Common Name

English

SHR8735

Code

English

2-Furancarboxylic acid, 5-[3-[(2Z)-2-[1,5-dihydro-3-methyl-5-oxo-1-(5,6,7,8-tetrahydro-2-naphthalenyl)-4H-pyrazol-4-ylidene]hydrazinyl]-2-hydroxyphenyl]-

Systematic Name

English

Classification Tree Code System Code

FDA ORPHAN DRUG

882322