U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry ACHIRAL
Molecular Formula C5H4Cl6O3
Molecular Weight 324.801
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of CLORETHATE

SMILES

ClC(Cl)(Cl)COC(=O)OCC(Cl)(Cl)Cl

InChI

InChIKey=IEPBPSSCIZTJIF-UHFFFAOYSA-N
InChI=1S/C5H4Cl6O3/c6-4(7,8)1-13-3(12)14-2-5(9,10)11/h1-2H2

HIDE SMILES / InChI
Molecular Formula C5H4Cl6O3
Molecular Weight 324.801
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Description

Clorethate is a hypnotic sedative drug, discovered by SmithKline in the 1960s. In mice, oral administration the drug leads to depression of spontaneous motor activity with ED50 of 288 mg/kg.

Approval Year

Unknown
149124
PubMed

PubMed

TitleDatePubMed
Trichloroethyl carbonate. I. Synthesis, physical properties, and pharmacology.
1967-07
Patents

Patents

US3193573A
1
Substance Class Chemical
Created
by admin
on Mon Mar 31 18:22:04 GMT 2025
Edited
by admin
on Mon Mar 31 18:22:04 GMT 2025
Record UNII
9VY0HXB11T
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
CLORETHATE
USAN  
USAN  
Official Name English
CLORETATE
INN  
INN  
Preferred Name English
CLORETHATE [USAN]
Common Name English
ETHANOL, 2,2,2-TRICHLORO-, CARBONATE
Systematic Name English
CHLORETHATE
Common Name English
NSC-15887
Code English
cloretate [INN]
Common Name English
Bis(2,2,2-trichloroethyl)carbonate
Systematic Name English
SK&F 12866
Code English
SK&F-12866
Code English
Classification Tree Code System Code
NCI_THESAURUS C29756
Created by admin on Mon Mar 31 18:22:05 GMT 2025 , Edited by admin on Mon Mar 31 18:22:05 GMT 2025
Code System Code Type Description
FDA UNII
9VY0HXB11T
Created by admin on Mon Mar 31 18:22:05 GMT 2025 , Edited by admin on Mon Mar 31 18:22:05 GMT 2025
PRIMARY
PUBCHEM
21851
Created by admin on Mon Mar 31 18:22:05 GMT 2025 , Edited by admin on Mon Mar 31 18:22:05 GMT 2025
PRIMARY
EVMPD
SUB06753MIG
Created by admin on Mon Mar 31 18:22:04 GMT 2025 , Edited by admin on Mon Mar 31 18:22:04 GMT 2025
PRIMARY
NSC
15887
Created by admin on Mon Mar 31 18:22:05 GMT 2025 , Edited by admin on Mon Mar 31 18:22:05 GMT 2025
PRIMARY
INN
1846
Created by admin on Mon Mar 31 18:22:04 GMT 2025 , Edited by admin on Mon Mar 31 18:22:04 GMT 2025
PRIMARY
NCI_THESAURUS
C80671
Created by admin on Mon Mar 31 18:22:04 GMT 2025 , Edited by admin on Mon Mar 31 18:22:04 GMT 2025
PRIMARY
SMS_ID
100000084004
Created by admin on Mon Mar 31 18:22:05 GMT 2025 , Edited by admin on Mon Mar 31 18:22:05 GMT 2025
PRIMARY
CAS
5634-37-7
Created by admin on Mon Mar 31 18:22:04 GMT 2025 , Edited by admin on Mon Mar 31 18:22:04 GMT 2025
PRIMARY
ChEMBL
CHEMBL2104188
Created by admin on Mon Mar 31 18:22:04 GMT 2025 , Edited by admin on Mon Mar 31 18:22:04 GMT 2025
PRIMARY
EPA CompTox
DTXSID20204881
Created by admin on Mon Mar 31 18:22:05 GMT 2025 , Edited by admin on Mon Mar 31 18:22:05 GMT 2025
PRIMARY
Related Record Type Details
Structure of CLORETHATE
ACTIVE MOIETY
NIH
NCATS
PRIVACY NOTICE
ACCESSIBILITY
DISCLAIMER
HHS VULNERABILITY DISCLOSURE
For language access assistance, contact the NCATS Public Information Officer
National Center for Advancing Translational Sciences (NCATS),
6701 Democracy Boulevard, Bethesda MD 20892-4874 • 301-594-8966