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Details

Stereochemistry ACHIRAL
Molecular Formula C6H8O4.2H4N
Molecular Weight 180.2022
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of DIAMMONIUM ADIPATE

SMILES

[NH4+].[NH4+].[O-]C(=O)CCCCC([O-])=O

InChI

InChIKey=ZRSKSQHEOZFGLJ-UHFFFAOYSA-N
InChI=1S/C6H10O4.2H3N/c7-5(8)3-1-2-4-6(9)10;;/h1-4H2,(H,7,8)(H,9,10);2*1H3

HIDE SMILES / InChI

Molecular Formula H3N
Molecular Weight 17.0305
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Molecular Formula C6H10O4
Molecular Weight 146.1412
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Adipic acid has been incorporated into controlled-release formulation matrix tablets to obtain a pH-independent release for both weakly basic and weakly acidic drugs. It has also been incorporated into the polymeric coating of hydrophilic monolithic systems to modulate the intragel pH, resulting in zero-order release of hydrophilic drugs. The disintegration at intestinal pH of the enteric polymer shellac has been reported to improve when adipic acid was used as a pore-forming agent without affecting release in the acidic media. Adipic acid is used to make bisobrin an antifibrinolytic.

Approval Year

Conditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
PubMed

PubMed

TitleDatePubMed
Compatibility study of trans-1,4,5,8-tetranitro-1,4,5,8-tetraazadecalin (TNAD) with some energetic components and inert materials.
2008-12-30
Determination of insulin in innovative formulations by means of LC coupled to fluorescence detection.
2008-12-15
Prenatal phenol and phthalate exposures and birth outcomes.
2008-08
Proteomic investigation of amino acid catabolism in the indigenous gut anaerobe Fusobacterium varium.
2008-07
Chemical modification of zinc hydroxide nitrate and Zn-Al-layered double hydroxide with dicarboxylic acids.
2008-04-01
Release profile comparison and stability of diltiazem-resin microcapsules in sustained release suspensions.
2008-03-20
Development of a liposaccharide-based delivery system and its application to the design of group A streptococcal vaccines.
2008-03-13
Diclofenac sodium loaded-cellulose acetate butyrate: effect of processing variables on microparticles properties, drug release kinetics and ulcerogenic activity.
2008-02
Ketotifen controlled release from cellulose acetate propionate and cellulose acetate butyrate membranes.
2008-02
Determination of phthalates and adipate in bottled water by headspace solid-phase microextraction and gas chromatography/mass spectrometry.
2008-01-18
Preparation and characterization of hydroxyapatite/poly(ethylene adipate) hybrid composites.
2008
Organic acid concentrations in amniotic fluid found in normal and Down syndrome pregnancies.
2008
Adipic and malonic acid aqueous solutions: surface tensions and saturation vapor pressures.
2007-12-20
Diverse entangled metal-organic framework materials incorporating kinked organodiimine and flexible aliphatic dicarboxylate ligands: synthesis, structure, physical properties, and reversible structural reorganization.
2007-09-03
[(3)H]Adenine is a suitable radioligand for the labeling of G protein-coupled adenine receptors but shows high affinity to bacterial contaminations in buffer solutions.
2007-09
Genome analysis of Minibacterium massiliensis highlights the convergent evolution of water-living bacteria.
2007-08
Host-guest adaptability within oxothiomolybdenum wheels: structures, studies in solution and DFT calculations.
2007-07-28
The relationship between instability of H2 production and compositions of bacterial communities within a dark fermentation fluidized-bed bioreactor.
2007-07-01
Magnetic resonance imaging findings of adult-onset glutaric aciduria type I.
2007-06
Synthesis and characterization of branched polymers from lipase-catalyzed trimethylolpropane copolymerizations.
2007-06
Exploring lanthanide luminescence in metal-organic frameworks: synthesis, structure, and guest-sensitized luminescence of a mixed europium/terbium-adipate framework and a terbium-adipate framework.
2007-05-14
Effect of the dispersion of Eudragit S100 powder on the properties of cellulose acetate butyrate microspheres containing theophylline made by the emulsion-solvent evaporation method.
2007-05
Cellulose acetate butyrate-pH/thermosensitive polymer microcapsules containing aminated poly(vinyl alcohol) microspheres for oral administration of DNA.
2007-04
Fluxome analysis using GC-MS.
2007-02-07
A novel multicompartimental system based on aminated poly(vinyl alcohol) microspheres/succinoylated pullulan microspheres for oral delivery of anionic drugs.
2007-02-07
[Physical, chemical and biological properties of food modified starches].
2007
Molecular model for host–guest interaction of tetraamino-tert-butylthiacalix[4]arene and tetraamino-tert-butylcalix[4]arene receptors with carboxylate and dicarboxylate guests: an ONIOM study.
2007
Enhancement of the Curie temperature by isomerization of diarylethene (DAE) for an organic-inorganic hybrid system: Co4(OH)7(DAE)0.5.3H2O.
2006-12-11
Prediction of estrogen receptor agonists and characterization of associated molecular descriptors by statistical learning methods.
2006-11
Facile preparation of biodegradable chitosan derivative having poly(butylene glycol adipate) side chains.
2006-08-15
Changes in bacterial community during fermentative hydrogen and acid production from organic waste by thermophilic anaerobic microflora.
2006-08
Ala-504 is a determinant of substrate binding affinity in the mouse Na(+)/dicarboxylate cotransporter.
2006-06
Modulatory effects of chitosan adipate on the T and B lymphocyte subsets in mice.
2006-06
Porous structures of polymer films prepared by spin coating with mixed solvents under humid condition.
2006-05-09
Modelling calcium carbonate biomineralisation processes.
2006-05
Crystal engineering of analogous and homologous organic compounds: hydrogen bonding patterns in trimethoprim hydrogen phthalate and trimethoprim hydrogen adipate.
2006-04-07
X-ray studies of crystalline complexes involving amino acids and peptides. XLIII. Adipic acid complexes of L- and DL-lysine.
2006-03
Amended final report of the safety assessment of dibutyl adipate as used in cosmetics.
2006
Matrix-assisted laser desorption/ionization time-of-flight/time-of-flight tandem mass spectra of poly(butylene adipate).
2006
catena-Poly[[mu-hexanedioato-1kappaO1:2kappaO6-bis[aqua(5-carboxypentanoato-kappaO)copper(II)]]-di-mu-4,4'-bipyridine-1kappaN:1'kappaN';2kappaN:2'kappaN'].
2005-12
Tweezing-adsorptive bubble separation. Analytical method for the selective and high enrichment of metalloenzymes.
2005-10-01
Increased biological hydrogen production with reduced organic loading.
2005-10
Uniaxial drawing of poly[(R)-3-hydroxybutyrate]/cellulose acetate butyrate blends and their orientation behavior.
2005-09-16
catena-Poly[[diaquabis(5-carboxypentanoato-kappaO)cobalt(II)]-mu-1,2-di-4-pyridylethane-kappa2N:N'].
2005-09
Production of 1,3-Propanediol by Clostridium butyricum VPI 3266 in continuous cultures with high yield and productivity.
2005-09
Clinic blood pressure responses to two amlodipine salt formulations, adipate and besylate, in adult Korean patients with mild to moderate hypertension: a multicenter, randomized, double-blind, parallel-group, 8-week comparison.
2005-06
Preparation and in vitro evaluation of propylthiouracil microspheres made of Eudragit RL 100 and cellulose acetate butyrate polymers using the emulsion-solvent evaporation method.
2005-05
Isolation and characterization of poly(butylene succinate-co-butylene adipate)-degrading microorganism.
2004
Characterization of a microorganism isolated from the effluent of hydrogen fermentation by microflora.
2001
Organic acids in aqueous humour and plasma: post mortem study in infants and diagnosis of enzymopathies.
1991
Patents

Sample Use Guides

In Vivo Use Guide
Unknown
Route of Administration: Unknown
In Vitro Use Guide
Unknown
Substance Class Chemical
Created
by admin
on Mon Mar 31 19:35:14 GMT 2025
Edited
by admin
on Mon Mar 31 19:35:14 GMT 2025
Record UNII
9VH76YE3HU
Record Status Validated (UNII)
Record Version
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Name Type Language
ADIPIC ACID, DIAMMONIUM SALT
Preferred Name English
DIAMMONIUM ADIPATE
Systematic Name English
HEXANEDIOIC ACID, AMMONIUM SALT (1:2)
Common Name English
HEXANEDIOIC ACID, DIAMMONIUM SALT
Common Name English
AMMONIUM ADIPATE
Systematic Name English
Code System Code Type Description
WIKIPEDIA
AMMONIUM ADIPATE
Created by admin on Mon Mar 31 19:35:14 GMT 2025 , Edited by admin on Mon Mar 31 19:35:14 GMT 2025
PRIMARY
FDA UNII
9VH76YE3HU
Created by admin on Mon Mar 31 19:35:14 GMT 2025 , Edited by admin on Mon Mar 31 19:35:14 GMT 2025
PRIMARY
ECHA (EC/EINECS)
222-196-9
Created by admin on Mon Mar 31 19:35:14 GMT 2025 , Edited by admin on Mon Mar 31 19:35:14 GMT 2025
PRIMARY
PUBCHEM
167786
Created by admin on Mon Mar 31 19:35:14 GMT 2025 , Edited by admin on Mon Mar 31 19:35:14 GMT 2025
PRIMARY
EPA CompTox
DTXSID30889466
Created by admin on Mon Mar 31 19:35:14 GMT 2025 , Edited by admin on Mon Mar 31 19:35:14 GMT 2025
PRIMARY
CAS
3385-41-9
Created by admin on Mon Mar 31 19:35:14 GMT 2025 , Edited by admin on Mon Mar 31 19:35:14 GMT 2025
PRIMARY
Related Record Type Details
PARENT -> SALT/SOLVATE