GUAIARETIC ACID

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C20H24O4
Molecular Weight	328.4022
Optical Activity	UNSPECIFIED
Defined Stereocenters	1 / 1
E/Z Centers	1
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

COC1=CC(C[C@@H](C)C(\C)=C/C2=CC=C(O)C(OC)=C2)=CC=C1O

InChI

InChIKey=OPAORDVBZRVVNQ-RNQWEJQRSA-N

InChI=1S/C20H24O4/c1-13(9-15-5-7-17(21)19(11-15)23-3)14(2)10-16-6-8-18(22)20(12-16)24-4/h5-9,11-12,14,21-22H,10H2,1-4H3/b13-9-/t14-/m1/s1

HIDE SMILES / InChI

Molecular Formula	C20H24O4
Molecular Weight	328.4022
Charge	0
Count

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	1 / 1
E/Z Centers	1
Optical Activity	UNSPECIFIED

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/7892296 | https://www.ncbi.nlm.nih.gov/pubmed/15814253 | pubs.rsc.org/en/content/articlehtml/1934/jr/jr9340001423

Guaiaretic acid is a constituent of guaiacum resin and closely related to Nordihydroguaiaretic acid an antioxidant compound found in the creosote bush (Larrea tridentata) which has been more widely studied. Guaiaretic acid is the dehydrogenated form of Nordihydroguaiaretic acid.

Originator

Approval Year

Conditions

Condition	Modality	Targets	Highest Phase	Product
Unknown 2596

PubMed

Title	Date	PubMed
Chemical studies of phytoestrogens and related compounds in dietary supplements: flax and chaparral.	1995-01	7892296

Patents

Sample Use Guides

In Vivo Use Guide

Unknown

Route of Administration: Unknown

In Vitro Use Guide

Unknown

Substance Class	Chemical Created by `admin` on `Mon Mar 31 21:14:43 GMT 2025` Edited by `admin` on `Mon Mar 31 21:14:43 GMT 2025`
Record UNII	9U7RAA1SKY
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

GUAIARETIC ACID

Common Name

English

GUAIACIC ACID

Preferred Name

English

PHENOL, 4,4'-((1Z,3R)-2,3-DIMETHYL-1-BUTENE-1,4-DIYL)BIS(2-METHOXY-

Systematic Name

English

Code System Code Type Description

PUBCHEM

9905497

Created by admin on Mon Mar 31 21:14:43 GMT 2025 , Edited by admin on Mon Mar 31 21:14:43 GMT 2025

PRIMARY

CAS

500-40-3

Created by admin on Mon Mar 31 21:14:43 GMT 2025 , Edited by admin on Mon Mar 31 21:14:43 GMT 2025

PRIMARY

FDA UNII

9U7RAA1SKY

Created by admin on Mon Mar 31 21:14:43 GMT 2025 , Edited by admin on Mon Mar 31 21:14:43 GMT 2025

PRIMARY

Details

SMILES

InChI

DescriptionSources: https://www.ncbi.nlm.nih.gov/pubmed/7892296 | https://www.ncbi.nlm.nih.gov/pubmed/15814253 | pubs.rsc.org/en/content/articlehtml/1934/jr/jr9340001423

Originator

Approval Year

Conditions

PubMed

Patents

Sample Use Guides

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/7892296 | https://www.ncbi.nlm.nih.gov/pubmed/15814253 | pubs.rsc.org/en/content/articlehtml/1934/jr/jr9340001423