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Details

Stereochemistry ACHIRAL
Molecular Formula 2Al.2Mg.2O.3O3Si.H2O
Molecular Weight 380.8383
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of SILODRATE

SMILES

O.[O--].[O--].[Mg++].[Mg++].[Al+3].[Al+3].[O-][Si]([O-])=O.[O-][Si]([O-])=O.[O-][Si]([O-])=O

InChI

InChIKey=JAUGGEIKQIHSMF-UHFFFAOYSA-N
InChI=1S/2Al.2Mg.3O3Si.H2O.2O/c;;;;3*1-4(2)3;;;/h;;;;;;;1H2;;/q2*+3;2*+2;3*-2;;2*-2

HIDE SMILES / InChI
Molecular Formula O3Si
Molecular Weight 76.0837
Charge -2
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE
Molecular Formula Mg
Molecular Weight 24.305
Charge 2
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE
Molecular Formula Al
Molecular Weight 26.9815386
Charge 3
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE
Molecular Formula HO
Molecular Weight 17.0073
Charge -1
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Description

Magnesium aluminosilicate is an antacid, it is used in combination with magnesium hydroxide to relieve heartburn.

Approval Year

1955
124
Conditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
Primary
Not Provided
511
Unknown

Approved Use

Unknown
PubMed

PubMed

TitleDatePubMed
The ability of antacids and cholestyramine to bind bile acids: effect of pH.
1986-09
Patents

Patents

US8652447
2

Sample Use Guides

In Vivo Use Guide
adults and children 12 years and over: Take 1 bottle (30mL) at a time 2 times daily, between meals, or as directed by a doctor
Route of Administration: Oral
In Vitro Use Guide
Unknown
Substance Class Chemical
Created
by admin
on Wed Apr 02 07:03:27 GMT 2025
Edited
by admin
on Wed Apr 02 07:03:27 GMT 2025
Record UNII
9T3UU8T0QK
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
MAGNESIUM ALUMINOMETASILICATE
INCI   JAN  
INCI  
Preferred Name English
SILODRATE
USAN  
USAN  
Official Name English
Simaldrate [WHO-DD]
Common Name English
simaldrate [INN]
Common Name English
SIMALDRATE
INN   WHO-DD  
INN  
Official Name English
MAGNESIUM ALUMINOMETASILICATE [EP MONOGRAPH]
Common Name English
MAGNESIUM ALUMINOMETASILICATE [JAN]
Common Name English
Aluminosilicic acid (H4Al2Si3O11), magnesium salt (1:2) hydrate
Common Name English
SILODRATE [USAN]
Common Name English
MP-1051
Code English
Classification Tree Code System Code
NCI_THESAURUS C78276
Created by admin on Wed Apr 02 07:03:27 GMT 2025 , Edited by admin on Wed Apr 02 07:03:27 GMT 2025
Code System Code Type Description
DRUG BANK
DB14116
Created by admin on Wed Apr 02 07:03:27 GMT 2025 , Edited by admin on Wed Apr 02 07:03:27 GMT 2025
PRIMARY
INN
1886
Created by admin on Wed Apr 02 07:03:27 GMT 2025 , Edited by admin on Wed Apr 02 07:03:27 GMT 2025
PRIMARY
RXCUI
236730
Created by admin on Wed Apr 02 07:03:27 GMT 2025 , Edited by admin on Wed Apr 02 07:03:27 GMT 2025
ALTERNATIVE
NCI_THESAURUS
C152361
Created by admin on Wed Apr 02 07:03:27 GMT 2025 , Edited by admin on Wed Apr 02 07:03:27 GMT 2025
PRIMARY
EPA CompTox
DTXSID30924725
Created by admin on Wed Apr 02 07:03:27 GMT 2025 , Edited by admin on Wed Apr 02 07:03:27 GMT 2025
PRIMARY
RXCUI
1373351
Created by admin on Wed Apr 02 07:03:27 GMT 2025 , Edited by admin on Wed Apr 02 07:03:27 GMT 2025
PRIMARY
EVMPD
SUB20645
Created by admin on Wed Apr 02 07:03:27 GMT 2025 , Edited by admin on Wed Apr 02 07:03:27 GMT 2025
PRIMARY
DAILYMED
9T3UU8T0QK
Created by admin on Wed Apr 02 07:03:27 GMT 2025 , Edited by admin on Wed Apr 02 07:03:27 GMT 2025
PRIMARY
FDA UNII
9T3UU8T0QK
Created by admin on Wed Apr 02 07:03:27 GMT 2025 , Edited by admin on Wed Apr 02 07:03:27 GMT 2025
PRIMARY
PUBCHEM
56841623
Created by admin on Wed Apr 02 07:03:27 GMT 2025 , Edited by admin on Wed Apr 02 07:03:27 GMT 2025
PRIMARY
ChEMBL
CHEMBL2108116
Created by admin on Wed Apr 02 07:03:27 GMT 2025 , Edited by admin on Wed Apr 02 07:03:27 GMT 2025
PRIMARY
ChEMBL
CHEMBL2109131
Created by admin on Wed Apr 02 07:03:27 GMT 2025 , Edited by admin on Wed Apr 02 07:03:27 GMT 2025
PRIMARY
CAS
12408-47-8
Created by admin on Wed Apr 02 07:03:27 GMT 2025 , Edited by admin on Wed Apr 02 07:03:27 GMT 2025
PRIMARY
Related Record Type Details
Structure of SILODRATE ANHYDROUS
ANHYDROUS->SOLVATE
Structure of SILODRATE ANHYDROUS
PARENT -> SALT/SOLVATE
Related Record Type Details
Structure of SILODRATE ANHYDROUS
ACTIVE MOIETY
NIH
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