Details
Stereochemistry | ACHIRAL |
Molecular Formula | C9H11NO2 |
Molecular Weight | 165.1891 |
Optical Activity | NONE |
Defined Stereocenters | 0 / 0 |
E/Z Centers | 0 |
Charge | 0 |
SHOW SMILES / InChI
SMILES
OC1=CC2=C(CNCC2)C=C1O
InChI
InChIKey=MBFUSGLXKQWVDW-UHFFFAOYSA-N
InChI=1S/C9H11NO2/c11-8-3-6-1-2-10-5-7(6)4-9(8)12/h3-4,10-12H,1-2,5H2
Molecular Formula | C9H11NO2 |
Molecular Weight | 165.1891 |
Charge | 0 |
Count |
|
Stereochemistry | ACHIRAL |
Additional Stereochemistry | No |
Defined Stereocenters | 0 / 0 |
E/Z Centers | 0 |
Optical Activity | NONE |
Approval Year
PubMed
Title | Date | PubMed |
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Uptake of the dopaminergic neurotoxin, norsalsolinol, into PC12 cells via dopamine transporter. | 2001 Jun |
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Inhibitory effects of endogenous dopaminergic neurotoxin, norsalsolinol on dopamine secretion in PC12 rat pheochromocytoma cells. | 2001 Jun |
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Norsalsolinol uptake into secretory vesicles via vesicular monoamine transporter and its secretion by membrane depolarization or purinoceptor stimulation in PC12 cells. | 2001 May |
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Simultaneous gas chromatographic-mass spectrometric determination of dopamine, norsalsolinol and salsolinol enantiomers in brain samples of a large human collective. | 2003 Jul |
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N-methyl-norsalsolinol modulates serotonin metabolism in the rat caudate nucleus: correlation with behavioural changes. | 2003 Mar |
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Increased systemic levels of norsalsolinol derivatives are induced by levodopa treatment and do not represent biological markers of Parkinson's disease. | 2004 Apr |
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Reactions of D-glucose with phenolic amino acids: further insights into the competition between Maillard and Pictet-Spengler condensation pathways. | 2005 Dec 30 |
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Systematic regional study of dopamine, norsalsolinol, and (R/S)-salsolinol levels in human brain areas of alcoholics. | 2005 Jan |
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Tetrahydroisoquinoline derivatives: a new perspective on monoaminergic dysfunction in children with ADHD? | 2007 Dec 10 |
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Localization of N-methyl-norsalsolinol within rodent and human brain. | 2008 Aug 15 |
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SAR studies of capsazepinoid bronchodilators. Part 2: Chlorination and catechol replacement in the A-ring. | 2008 Mar 1 |
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Endogenous tetrahydroisoquinolines associated with Parkinson's disease mimic the feedback inhibition of tyrosine hydroxylase by catecholamines. | 2008 May |
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The mechanisms of oxidative DNA damage and apoptosis induced by norsalsolinol, an endogenous tetrahydroisoquinoline derivative associated with Parkinson's disease. | 2009 Jan |
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Determination of salsolinol, norsalsolinol, and twenty-one biogenic amines using micellar electrokinetic capillary chromatography-electrochemical detection. | 2010 Jun |
Patents
Substance Class |
Chemical
Created
by
admin
on
Edited
Fri Dec 15 19:38:41 GMT 2023
by
admin
on
Fri Dec 15 19:38:41 GMT 2023
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Record UNII |
9SPO03ZH41
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Record Status |
Validated (UNII)
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Record Version |
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DTXSID90188366
Created by
admin on Fri Dec 15 19:38:41 GMT 2023 , Edited by admin on Fri Dec 15 19:38:41 GMT 2023
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NORSALSOLINOL
Created by
admin on Fri Dec 15 19:38:41 GMT 2023 , Edited by admin on Fri Dec 15 19:38:41 GMT 2023
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34827-33-3
Created by
admin on Fri Dec 15 19:38:41 GMT 2023 , Edited by admin on Fri Dec 15 19:38:41 GMT 2023
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9SPO03ZH41
Created by
admin on Fri Dec 15 19:38:41 GMT 2023 , Edited by admin on Fri Dec 15 19:38:41 GMT 2023
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36937
Created by
admin on Fri Dec 15 19:38:41 GMT 2023 , Edited by admin on Fri Dec 15 19:38:41 GMT 2023
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