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Details

Stereochemistry ACHIRAL
Molecular Formula C9H11NO2
Molecular Weight 165.1891
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of NORSALSOLINOL

SMILES

OC1=CC2=C(CNCC2)C=C1O

InChI

InChIKey=MBFUSGLXKQWVDW-UHFFFAOYSA-N
InChI=1S/C9H11NO2/c11-8-3-6-1-2-10-5-7(6)4-9(8)12/h3-4,10-12H,1-2,5H2

HIDE SMILES / InChI

Molecular Formula C9H11NO2
Molecular Weight 165.1891
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Approval Year

PubMed

PubMed

TitleDatePubMed
Uptake of the dopaminergic neurotoxin, norsalsolinol, into PC12 cells via dopamine transporter.
2001 Jun
Inhibitory effects of endogenous dopaminergic neurotoxin, norsalsolinol on dopamine secretion in PC12 rat pheochromocytoma cells.
2001 Jun
Norsalsolinol uptake into secretory vesicles via vesicular monoamine transporter and its secretion by membrane depolarization or purinoceptor stimulation in PC12 cells.
2001 May
Simultaneous gas chromatographic-mass spectrometric determination of dopamine, norsalsolinol and salsolinol enantiomers in brain samples of a large human collective.
2003 Jul
N-methyl-norsalsolinol modulates serotonin metabolism in the rat caudate nucleus: correlation with behavioural changes.
2003 Mar
Increased systemic levels of norsalsolinol derivatives are induced by levodopa treatment and do not represent biological markers of Parkinson's disease.
2004 Apr
Reactions of D-glucose with phenolic amino acids: further insights into the competition between Maillard and Pictet-Spengler condensation pathways.
2005 Dec 30
Systematic regional study of dopamine, norsalsolinol, and (R/S)-salsolinol levels in human brain areas of alcoholics.
2005 Jan
Tetrahydroisoquinoline derivatives: a new perspective on monoaminergic dysfunction in children with ADHD?
2007 Dec 10
Localization of N-methyl-norsalsolinol within rodent and human brain.
2008 Aug 15
SAR studies of capsazepinoid bronchodilators. Part 2: Chlorination and catechol replacement in the A-ring.
2008 Mar 1
Endogenous tetrahydroisoquinolines associated with Parkinson's disease mimic the feedback inhibition of tyrosine hydroxylase by catecholamines.
2008 May
The mechanisms of oxidative DNA damage and apoptosis induced by norsalsolinol, an endogenous tetrahydroisoquinoline derivative associated with Parkinson's disease.
2009 Jan
Determination of salsolinol, norsalsolinol, and twenty-one biogenic amines using micellar electrokinetic capillary chromatography-electrochemical detection.
2010 Jun
Patents

Patents

Substance Class Chemical
Created
by admin
on Fri Dec 15 19:38:41 GMT 2023
Edited
by admin
on Fri Dec 15 19:38:41 GMT 2023
Record UNII
9SPO03ZH41
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
NORSALSOLINOL
Common Name English
6,7-DIHYDROXYTETRAHYDROISOQUINOLINE
Systematic Name English
TETRAHYDRO-6,7-ISOQUINOLINEDIOL
Systematic Name English
1,2,3,4-TETRAHYDROISOQUINOLINE-6,7-DIOL
Systematic Name English
6,7-ISOQUINOLINEDIOL, 1,2,3,4-TETRAHYDRO-
Systematic Name English
6,7-DIHYDROXY-1,2,3,4-TETRAHYDROISOQUINOLINE
Systematic Name English
Code System Code Type Description
EPA CompTox
DTXSID90188366
Created by admin on Fri Dec 15 19:38:41 GMT 2023 , Edited by admin on Fri Dec 15 19:38:41 GMT 2023
PRIMARY
WIKIPEDIA
NORSALSOLINOL
Created by admin on Fri Dec 15 19:38:41 GMT 2023 , Edited by admin on Fri Dec 15 19:38:41 GMT 2023
PRIMARY
CAS
34827-33-3
Created by admin on Fri Dec 15 19:38:41 GMT 2023 , Edited by admin on Fri Dec 15 19:38:41 GMT 2023
PRIMARY
FDA UNII
9SPO03ZH41
Created by admin on Fri Dec 15 19:38:41 GMT 2023 , Edited by admin on Fri Dec 15 19:38:41 GMT 2023
PRIMARY
PUBCHEM
36937
Created by admin on Fri Dec 15 19:38:41 GMT 2023 , Edited by admin on Fri Dec 15 19:38:41 GMT 2023
PRIMARY