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Details

Stereochemistry ACHIRAL
Molecular Formula C9H11NO2
Molecular Weight 165.1891
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of NORSALSOLINOL

SMILES

OC1=C(O)C=C2CNCCC2=C1

InChI

InChIKey=MBFUSGLXKQWVDW-UHFFFAOYSA-N
InChI=1S/C9H11NO2/c11-8-3-6-1-2-10-5-7(6)4-9(8)12/h3-4,10-12H,1-2,5H2

HIDE SMILES / InChI

Molecular Formula C9H11NO2
Molecular Weight 165.1891
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Approval Year

PubMed

PubMed

TitleDatePubMed
Determination of salsolinol, norsalsolinol, and twenty-one biogenic amines using micellar electrokinetic capillary chromatography-electrochemical detection.
2010-06
The mechanisms of oxidative DNA damage and apoptosis induced by norsalsolinol, an endogenous tetrahydroisoquinoline derivative associated with Parkinson's disease.
2009-01
Localization of N-methyl-norsalsolinol within rodent and human brain.
2008-08-15
Endogenous tetrahydroisoquinolines associated with Parkinson's disease mimic the feedback inhibition of tyrosine hydroxylase by catecholamines.
2008-05
SAR studies of capsazepinoid bronchodilators. Part 2: Chlorination and catechol replacement in the A-ring.
2008-03-01
Tetrahydroisoquinoline derivatives: a new perspective on monoaminergic dysfunction in children with ADHD?
2007-12-10
Reactions of D-glucose with phenolic amino acids: further insights into the competition between Maillard and Pictet-Spengler condensation pathways.
2005-12-30
Systematic regional study of dopamine, norsalsolinol, and (R/S)-salsolinol levels in human brain areas of alcoholics.
2005-01
Increased systemic levels of norsalsolinol derivatives are induced by levodopa treatment and do not represent biological markers of Parkinson's disease.
2004-04
Simultaneous gas chromatographic-mass spectrometric determination of dopamine, norsalsolinol and salsolinol enantiomers in brain samples of a large human collective.
2003-07
N-methyl-norsalsolinol modulates serotonin metabolism in the rat caudate nucleus: correlation with behavioural changes.
2003-03
Uptake of the dopaminergic neurotoxin, norsalsolinol, into PC12 cells via dopamine transporter.
2001-06
Inhibitory effects of endogenous dopaminergic neurotoxin, norsalsolinol on dopamine secretion in PC12 rat pheochromocytoma cells.
2001-06
Norsalsolinol uptake into secretory vesicles via vesicular monoamine transporter and its secretion by membrane depolarization or purinoceptor stimulation in PC12 cells.
2001-05
Patents

Patents

Substance Class Chemical
Created
by admin
on Mon Mar 31 19:51:56 GMT 2025
Edited
by admin
on Mon Mar 31 19:51:56 GMT 2025
Record UNII
9SPO03ZH41
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
NORSALSOLINOL
Common Name English
1,2,3,4-TETRAHYDROISOQUINOLINE-6,7-DIOL
Preferred Name English
6,7-DIHYDROXYTETRAHYDROISOQUINOLINE
Systematic Name English
TETRAHYDRO-6,7-ISOQUINOLINEDIOL
Systematic Name English
6,7-ISOQUINOLINEDIOL, 1,2,3,4-TETRAHYDRO-
Systematic Name English
6,7-DIHYDROXY-1,2,3,4-TETRAHYDROISOQUINOLINE
Systematic Name English
Code System Code Type Description
EPA CompTox
DTXSID90188366
Created by admin on Mon Mar 31 19:51:56 GMT 2025 , Edited by admin on Mon Mar 31 19:51:56 GMT 2025
PRIMARY
WIKIPEDIA
NORSALSOLINOL
Created by admin on Mon Mar 31 19:51:56 GMT 2025 , Edited by admin on Mon Mar 31 19:51:56 GMT 2025
PRIMARY
CAS
34827-33-3
Created by admin on Mon Mar 31 19:51:56 GMT 2025 , Edited by admin on Mon Mar 31 19:51:56 GMT 2025
PRIMARY
FDA UNII
9SPO03ZH41
Created by admin on Mon Mar 31 19:51:56 GMT 2025 , Edited by admin on Mon Mar 31 19:51:56 GMT 2025
PRIMARY
PUBCHEM
36937
Created by admin on Mon Mar 31 19:51:56 GMT 2025 , Edited by admin on Mon Mar 31 19:51:56 GMT 2025
PRIMARY