Plencifgene Parvec

Approval Year

Substance Class	Structurally Diverse Created by `admin` on `Wed Apr 02 18:04:34 GMT 2025` Edited by `admin` on `Wed Apr 02 18:04:34 GMT 2025`
Source Materials Class	ORGANISM
Source Materials Type	RECOMBINANT VIRUS
Source Materials State	LIVE NON-REPLICATING GENETICALLY MODIFIED
Organism Family	Parvoviridae
Organism Genus	Dependoparvovirus
Organism Species	adeno-associated dependoparvovirus a
Infraspecific Type	RECOMBINANT VECTOR
Infraspecific Name	4D-A101.CMV173-CFTR?R
Part	whole
Record UNII	9SG6QLJ7VJ
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

Plencifgene Parvec

Official Name

English

4D-710

Preferred Name

English

plencifgene parvec [INN]

Common Name

English

recombinant replication-defective adeno-associated virus vector 4D-710 cytomegalovirus promoter CMV173 plus human (1-707)-(760-1480)-cystic fibrosis transmembrane conductance regulator codon-optimized gene CFTR?R plus synthetic polyadenylation signal plu

Common Name

English

recombinant, non-replicating adeno-associated virus (AAV) vector (with capsid variant A101) encoding codon-optimised human cystic fibrosis transmembrane conductance regulator (CFTR) with the regulatory domain deleted (CFTR?R), under control of a 173bp cy

Common Name

English

Code System Code Type Description

INN

13321

Created by admin on Wed Apr 02 18:04:34 GMT 2025 , Edited by admin on Wed Apr 02 18:04:34 GMT 2025

PRIMARY

CAS

2737363-32-3

Created by admin on Wed Apr 02 18:04:34 GMT 2025 , Edited by admin on Wed Apr 02 18:04:34 GMT 2025

PRIMARY

FDA UNII

9SG6QLJ7VJ

Created by admin on Wed Apr 02 18:04:34 GMT 2025 , Edited by admin on Wed Apr 02 18:04:34 GMT 2025

PRIMARY

Related Record Type Details


					9SG6QLJ7VJ

Plencifgene Parvec

ACTIVE MOIETY

Amount:

Structural Modifications

Modification Type	Location Site	Location Type	Residue Modified	Extent	Fragment Name	Fragment Approval
INSERTED GENE EXPRESSION VECTOR					Plencifgene parvec transgene insert	MNG6B6YGE4