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Details

Stereochemistry RACEMIC
Molecular Formula C27H52O5
Molecular Weight 456.6988
Optical Activity ( + / - )
Defined Stereocenters 0 / 1
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of GLYCERYL 1,2-DILAURATE

SMILES

CCCCCCCCCCCC(=O)OCC(CO)OC(=O)CCCCCCCCCCC

InChI

InChIKey=OQQOAWVKVDAJOI-UHFFFAOYSA-N
InChI=1S/C27H52O5/c1-3-5-7-9-11-13-15-17-19-21-26(29)31-24-25(23-28)32-27(30)22-20-18-16-14-12-10-8-6-4-2/h25,28H,3-24H2,1-2H3

HIDE SMILES / InChI

Molecular Formula C27H52O5
Molecular Weight 456.6988
Charge 0
Count
Stereochemistry RACEMIC
Additional Stereochemistry No
Defined Stereocenters 0 / 1
E/Z Centers 0
Optical Activity ( + / - )

Glyceryl 1,2-dilaurate is the fatty acid diester of glycerol. Glyceryl diesters, on a whole, are FDA and CIR approved and are given the GRAS rating. It is used as an emollient (skin conditioning agent) in cosmetics for increasing the "body" and viscosity of emulsions and improving the elegance of low-cost formulations. In addition, it may be used for the preparation of nanolipid carriers for drug delivery.

Approval Year

Conditions

Conditions

ConditionModalityTargetsHighest PhaseProduct
PubMed

PubMed

TitleDatePubMed
Amended final report on the safety assessment of glyceryl dilaurate, glyceryl diarachidate, glyceryl dibehenate, glyceryl dierucate, glyceryl dihydroxystearate, glyceryl diisopalmitate, glyceryl diisostearate, glyceryl dilinoleate, glyceryl dimyristate, glyceryl dioleate, glyceryl diricinoleate, glyceryl dipalmitate, glyceryl dipalmitoleate, glyceryl distearate, glyceryl palmitate lactate, glyceryl stearate citrate, glyceryl stearate lactate, and glyceryl stearate succinate.
2007
Parasite impairment by targeting Plasmodium-infected RBCs using glyceryl-dilaurate nanostructured lipid carriers.
2014 Aug

Sample Use Guides

Glyceryl dilaurate (up to 5%) is used as a skin conditioning agent - emollient in cosmetics.
Route of Administration: Transdermal
In Vitro Use Guide
Unknown
Substance Class Chemical
Created
by admin
on Fri Dec 15 15:13:37 GMT 2023
Edited
by admin
on Fri Dec 15 15:13:37 GMT 2023
Record UNII
9S1016G3A2
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
GLYCERYL 1,2-DILAURATE
Common Name English
1,2-DILAUROYL-RAC-GLYCEROL
Common Name English
GLYCEROL 1,2-DIDODECANOATE
Common Name English
1,2-DILAURIN
Common Name English
1,2-O-DILAUROYLGLYCEROL
Systematic Name English
GLYCEROL 1,2-DILAURATE
Common Name English
LAURIN, 1,2-DI-
Common Name English
DODECANOIC ACID, 1-(HYDROXYMETHYL)-1,2-ETHANEDIYL ESTER
Common Name English
Code System Code Type Description
CAS
17598-94-6
Created by admin on Fri Dec 15 15:13:37 GMT 2023 , Edited by admin on Fri Dec 15 15:13:37 GMT 2023
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FDA UNII
9S1016G3A2
Created by admin on Fri Dec 15 15:13:37 GMT 2023 , Edited by admin on Fri Dec 15 15:13:37 GMT 2023
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EPA CompTox
DTXSID30880897
Created by admin on Fri Dec 15 15:13:37 GMT 2023 , Edited by admin on Fri Dec 15 15:13:37 GMT 2023
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PUBCHEM
33979
Created by admin on Fri Dec 15 15:13:37 GMT 2023 , Edited by admin on Fri Dec 15 15:13:37 GMT 2023
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