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Details

Stereochemistry RACEMIC
Molecular Formula C19H29NO.ClH
Molecular Weight 323.901
Optical Activity ( + / - )
Defined Stereocenters 0 / 1
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of CYCRIMINE HYDROCHLORIDE

SMILES

Cl.OC(CCN1CCCCC1)(C2CCCC2)C3=CC=CC=C3

InChI

InChIKey=WBCWFMFZMRFRLT-UHFFFAOYSA-N
InChI=1S/C19H29NO.ClH/c21-19(18-11-5-6-12-18,17-9-3-1-4-10-17)13-16-20-14-7-2-8-15-20;/h1,3-4,9-10,18,21H,2,5-8,11-16H2;1H

HIDE SMILES / InChI

Molecular Formula C19H29NO
Molecular Weight 287.4397
Charge 0
Count
MOL RATIO 1 MOL RATIO (average)
Stereochemistry RACEMIC
Additional Stereochemistry No
Defined Stereocenters 0 / 1
E/Z Centers 0
Optical Activity ( + / - )

Molecular Formula ClH
Molecular Weight 36.461
Charge 0
Count
MOL RATIO 1 MOL RATIO (average)
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Description

CYCRIMINE is an antispasmodic drug used for the treatment of Parkinson's disease (PD). It binds the muscarinic acetylcholine receptor M1, effectively reducing levels of acetylcholine. This decrease in acetylcholine restores the normal dopamine-acetylcholine balance and relieves the symptoms of PD.

CNS Activity

Approval Year

Targets

Primary TargetPharmacologyConditionPotency

Conditions

ConditionModalityTargetsHighest PhaseProduct
Primary
Pagitane

Funbound

ValueDoseCo-administeredAnalytePopulation
79%
2.5 mg 4 times / day unknown, oral
CYCRIMINE plasma
Homo sapiens

PubMed

Substance Class Chemical
Record UNII
9RB4L4K895
Record Status Validated (UNII)
Record Version