Opemalirsen sodium

Approval Year

Substance Class	Nucleic Acid Created by `admin` on `Wed Apr 02 05:51:10 GMT 2025` Edited by `admin` on `Wed Apr 02 05:51:10 GMT 2025`
Nucleic Acid Type	OLIGONUCLEOTIDE
Sequence Origin	HUMAN
Sequence Type	COMPLETE
Record UNII	9PXX7147R2
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

Opemalirsen sodium

Official Name

English

AZD-2373 SODIUM

Preferred Name

English

DNA, d(P-thio)([2?,5?-anhydro-6?-deoxy-4?-C-(hydroxymethyl)-?-L-mannofurano]m<sup>5</sup>rU-(3??4?)-[2?,5?-anhydro-6?-deoxy-4?-C-(hydroxymethyl)-?-L-mannofurano]m<sup>5</sup>rU-(3??4?)-[2?,5?-anhydro-6?-deoxy-4?-C-(hydroxymethyl)-?-L-mannofurano](3??4?)m

Common Name

English

all-P-ambo-2'-O,4'-C-[(1S)-ethane-1,1-diyl]-5-methyl-P-thiouridylyl-(3'?5')-2'-O,4'-C-[(1S)-ethane-1,1-diyl]-5-methyl-P-thiouridylyl-(3'?5')-2'-O,4'-C-[(1S)-ethane-1,1-diyl]-5-methyl-P-thiouridylyl-(3'?5')-P-thiothymidylyl-(3'?5')-2'-deoxy-P-thioguanylyl

Common Name

English

ION-972190 SODIUM

Code

English

AZD2373 SODIUM

Code

English

OPEMALIRSEN SODIUM [USAN]

Common Name

English

Code System Code Type Description

FDA UNII

9PXX7147R2

Created by admin on Wed Apr 02 05:51:10 GMT 2025 , Edited by admin on Wed Apr 02 05:51:10 GMT 2025

PRIMARY

USAN

MN-243

Created by admin on Wed Apr 02 05:51:10 GMT 2025 , Edited by admin on Wed Apr 02 05:51:10 GMT 2025

PRIMARY

CAS

2639854-33-2

Created by admin on Wed Apr 02 05:51:10 GMT 2025 , Edited by admin on Wed Apr 02 05:51:10 GMT 2025

PRIMARY

NCI_THESAURUS

C213391

Created by admin on Wed Apr 02 05:51:10 GMT 2025 , Edited by admin on Wed Apr 02 05:51:10 GMT 2025

PRIMARY

Sugar	Site Range	Site Count
2'-O-Methoxyethyl ribose	1_16	1 / 16
	1_1-1_3;1_13-1_15	6 / 16
Deoxyribose (DNA)	1_4-1_12	9 / 16

Linkage	Site Range	Site Count
Sodium Phosporothioate	1_2-1_16	15 / 15